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uvrC uvrC BP2338 BP2338 dnaK dnaK motB motB ompA ompA secG secG proB proB secE secE cheW cheW cheA cheA dltB dltB secA secA uvrA uvrA ctaD ctaD secF secF secD secD prfB prfB flgE flgE fliN fliN fliM fliM fliL fliL smpB smpB rpmG rpmG cheB cheB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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uvrCPutative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (609 aa)
BP2338Putative transport protein; Similar to proteins thought to be involved in phosphate transport eg. Pseudomonas putida phosphate transport system protein PhoU SW:PHOU_PSEPU (Q9Z410) (256 aa) fasta scores: E(): 6.3e-38, 46.98% id in 249 aa, and to Escherichia coli phosphate transport system protein PhoU or nmpa or b3724 SW:PHOU_ECOLI (P07656) (241 aa) fasta scores: E(): 2.3e-29, 40.92% id in 237 aa. (268 aa)
dnaKMolecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. (641 aa)
motBSimilar to Escherichia coli chemotaxis MotB protein MotB or B1889 or Z2943 or Ecs2599 SW:MOTB_ECOLI (P09349) (308 aa) fasta scores: E(): 8.5e-54, 57.500% id in 280 aa, and to Salmonella typhimurium chemotaxis MotB protein MotB SW:MOTB_SALTY (P55892) (309 aa) fasta scores: E(): 9.8e-54, 58.156% id in 282 aa. (315 aa)
ompAHighly similar to Bordetella avium outer membrane protein A precursor OmpA SW:OMPA_BORAV (Q05146) (194 aa) fasta scores: E(): 5.7e-67, 91.753% id in 194 aa, and to Bordetella petrii OmpA protein OmpA TR:Q9S3M1 (EMBL:AJ242599) (152 aa) fasta scores: E(): 5.1e-49, 88.079% id in 151 aa. (193 aa)
secGProtein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (148 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (358 aa)
secEPreprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (126 aa)
cheWSimilar to Escherichia coli chemotaxis protein CheW or B1887 or Z2941 or Ecs2597 SW:CHEW_ECOLI (P07365) (167 aa) fasta scores: E(): 1.3e-41, 74.83% id in 155 aa, and to Burkholderia pseudomallei (Pseudomonas pseudomallei) chemotaxis protein CheW TR:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 7e-43, 72.56% id in 164 aa. (166 aa)
cheAChemotaxis protein CheY (Pseudogene); HMMPfam hit to PF00072, Response regulator receiver domain. (685 aa)
dltBPutative protein involved in the transfer of D-alanine into teichoic acids; Similar to Bacillus subtilis protein DltB thought to be involved in D-alanine transport SW:DLTB_BACSU (P39580) (395 aa) fasta scores: E(): 5.5e-25, 33.68% id in 282 aa, and to Lactococcus lactis peptidoglycan biosynthesis protein DltB TR:Q9CG50 (EMBL:AE006358) (407 aa) fasta scores: E(): 1.8e-23, 34.69% id in 245 aa; Belongs to the membrane-bound acyltransferase family. (375 aa)
secAPreprotein translocase secA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (911 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (952 aa)
ctaDCytochrome c oxidase polypeptide I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (535 aa)
secFProtein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (311 aa)
secDProtein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (626 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (367 aa)
flgESimilar to Salmonella typhimurium flagellar hook protein FlgE or FlaK or Fla FV SW:FLGE_SALTY (P16322) (402 aa) fasta scores: E(): 4e-24, 40.08% id in 479 aa, and to Escherichia coli flagellar hook protein FlgE or FlaK or Fla FV or B1076 SW:FLGE_ECOLI (P75937) (401 aa) fasta scores: E(): 1.8e-25, 40.08% id in 479 aa. (473 aa)
fliNSimilar to Escherichia coli flagellar motor switch protein FliN or MotD or FlaN or B1946 SW:FLIN_ECOLI (P15070) (137 aa) fasta scores: E(): 1.3e-23, 61.53% id in 130 aa, and to Salmonella typhimurium flagellar motor switch protein FliN or MotD or FlaNf SW:FLIN_SALTY (P26419) (137 aa) fasta scores: E(): 3.7e-24, 63.84% id in 130 aa. (166 aa)
fliMSimilar to Escherichia coli flagellar motor switch protein FliM or Fla AII or Fla QII or CheC2 or B1945 SW:FLIM_ECOLI (P06974) (334 aa) fasta scores: E(): 3.6e-66, 52.32% id in 323 aa, and to Salmonella typhimurium flagellar motor switch protein FliM or Fla AII or Fla QII or CheC2 SW:FLIM_SALTY (P26418) (334 aa) fasta scores: E(): 1.6e-67, 52.96% id in 321 aa. (336 aa)
fliLFlagellar protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (182 aa)
smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (155 aa)
rpmG50S ribosomal protein L33; Similar to e.g. Escherichia coli and Salmonella typhimurium 50S ribosomal protein L33, rpmG or B3636 SW:RL33_ECOLI (P02436) (54 aa) fasta scores: E(): 1.9e-14, 75.926% id in 54 aa; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
cheBChemotaxis protein methyltransferase (Pseudogene); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (350 aa)
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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