STRINGSTRING
SDM55847.1 SDM55847.1 SDM55877.1 SDM55877.1 SDM55914.1 SDM55914.1 SDM55950.1 SDM55950.1 SDM55985.1 SDM55985.1 SDM56048.1 SDM56048.1 SDM56081.1 SDM56081.1 SDM52832.1 SDM52832.1 SDM52868.1 SDM52868.1 SDM52909.1 SDM52909.1 SDM54898.1 SDM54898.1 fumC fumC SDM62495.1 SDM62495.1 SDM62526.1 SDM62526.1 SDM62393.1 SDM62393.1 SDM62426.1 SDM62426.1 SDM62465.1 SDM62465.1 pckG pckG SDM65846.1 SDM65846.1 SDM68037.1 SDM68037.1 SDM73977.1 SDM73977.1 SDM74015.1 SDM74015.1 SDM74055.1 SDM74055.1 SDM75191.1 SDM75191.1 SDM78158.1 SDM78158.1 SDM79037.1 SDM79037.1 ackA ackA SDM80524.1 SDM80524.1 SDM80593.1 SDM80593.1 SDM83908.1 SDM83908.1 SDM83397.1 SDM83397.1 SDM83473.1 SDM83473.1 SDM83505.1 SDM83505.1 SDM88786.1 SDM88786.1 SDM88832.1 SDM88832.1 SDM89816.1 SDM89816.1 SDM94957.1 SDM94957.1 SDM99256.1 SDM99256.1 SDN01065.1 SDN01065.1 SDN16608.1 SDN16608.1 SDN16476.1 SDN16476.1 SDN18764.1 SDN18764.1 SDN18797.1 SDN18797.1 SDN19075.1 SDN19075.1 SDN19108.1 SDN19108.1 SDN18633.1 SDN18633.1 SDN18673.1 SDN18673.1 SDN18734.1 SDN18734.1 dltC dltC SDN24717.1 SDN24717.1 SDN25785.1 SDN25785.1 SDN33185.1 SDN33185.1 SDN39483.1 SDN39483.1 SDN39673.1 SDN39673.1 SDN38786.1 SDN38786.1 SDN39916.1 SDN39916.1 SDN38813.1 SDN38813.1 SDN40342.1 SDN40342.1 SDN40385.1 SDN40385.1 SDN48873.1 SDN48873.1 SDN50969.1 SDN50969.1 SDN51009.1 SDN51009.1 SDN60208.1 SDN60208.1 SDN61680.1 SDN61680.1 SDN62003.1 SDN62003.1 SDN64361.1 SDN64361.1 SDN66818.1 SDN66818.1 SDN66894.1 SDN66894.1 SDN65904.1 SDN65904.1 SDN69058.1 SDN69058.1 SDN76128.1 SDN76128.1 SDN76179.1 SDN76179.1 SDN76227.1 SDN76227.1 SDN76266.1 SDN76266.1 SDN76347.1 SDN76347.1 SDN76384.1 SDN76384.1 SDN76423.1 SDN76423.1 SDN76552.1 SDN76552.1 SDN76597.1 SDN76597.1 SDN82688.1 SDN82688.1 SDN82723.1 SDN82723.1 fabH fabH SDN82803.1 SDN82803.1 acpP acpP accA accA accD accD SDN82514.1 SDN82514.1 SDN82556.1 SDN82556.1 SDN82595.1 SDN82595.1 SDN82634.1 SDN82634.1 SDN84454.1 SDN84454.1 SDN84485.1 SDN84485.1 SDN90713.1 SDN90713.1 SDN93190.1 SDN93190.1 ilvD ilvD leuA leuA SDN98681.1 SDN98681.1 leuC leuC leuD leuD leuB leuB SDN98374.1 SDN98374.1 SDN98517.1 SDN98517.1 SDN98545.1 SDN98545.1 ilvC ilvC SDO01532.1 SDO01532.1 SDO10225.1 SDO10225.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDM55847.1Stage II sporulation protein E (SpoIIE). (393 aa)
SDM55877.1Iron only hydrogenase large subunit, C-terminal domain. (569 aa)
SDM55914.1Thioredoxin-like [2Fe-2S] ferredoxin. (95 aa)
SDM55950.1Thioredoxin-like [2Fe-2S] ferredoxin. (91 aa)
SDM55985.1[FeFe] hydrogenase, group B1/B3. (500 aa)
SDM56048.1Pyruvate formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (237 aa)
SDM56081.1Formate C-acetyltransferase. (743 aa)
SDM52832.1Hypothetical protein. (216 aa)
SDM52868.1acetyl-CoA synthetase. (559 aa)
SDM52909.1Transcriptional regulator, XRE family with cupin sensor. (182 aa)
SDM54898.1Malate dehydrogenase (oxaloacetate-decarboxylating). (390 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (454 aa)
SDM62495.1Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (180 aa)
SDM62526.1NAD(P)-dependent iron-only hydrogenase diaphorase component iron-sulfur protein. (166 aa)
SDM62393.1NAD(P)-dependent iron-only hydrogenase catalytic subunit. (581 aa)
SDM62426.1NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein. (595 aa)
SDM62465.1NAD(P)-dependent iron-only hydrogenase iron-sulfur protein. (123 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (586 aa)
SDM65846.13-isopropylmalate dehydrogenase. (353 aa)
SDM68037.1Isopropylmalate/homocitrate/citramalate synthases. (459 aa)
SDM73977.1Oxaloacetate decarboxylase, alpha subunit. (466 aa)
SDM74015.1glutaconyl-CoA decarboxylase. (140 aa)
SDM74055.1Acetyl-CoA carboxylase, carboxyltransferase component. (454 aa)
SDM75191.1Major Facilitator Superfamily protein. (419 aa)
SDM78158.1BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. (270 aa)
SDM79037.1Hypothetical protein. (185 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
SDM80524.1Citrate synthase; Belongs to the citrate synthase family. (460 aa)
SDM80593.14Fe-4S dicluster domain-containing protein. (57 aa)
SDM83908.1Sodium pump decarboxylases, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family. (112 aa)
SDM83397.1fatty-acyl-CoA synthase. (554 aa)
SDM83473.1fatty-acyl-CoA synthase. (270 aa)
SDM83505.13-oxoacyl-[acyl-carrier protein] reductase. (244 aa)
SDM88786.1acetyl-CoA synthetase. (555 aa)
SDM88832.1Transcriptional regulator, XRE family with cupin sensor. (198 aa)
SDM89816.1Alcohol dehydrogenase, class IV. (367 aa)
SDM94957.1Protein of unknown function. (140 aa)
SDM99256.14Fe-4S binding domain-containing protein. (79 aa)
SDN01065.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (459 aa)
SDN16608.1D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily; Belongs to the membrane-bound acyltransferase family. (479 aa)
SDN16476.1Oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (390 aa)
SDN18764.1Iron-only hydrogenase maturation protein HydE. (347 aa)
SDN18797.1Putative iron-only hydrogenase system regulator. (95 aa)
SDN19075.1Hypothetical protein. (345 aa)
SDN19108.1DNA-binding transcriptional regulator, PadR family. (120 aa)
SDN18633.1Aspartate ammonia-lyase. (461 aa)
SDN18673.1Iron-only hydrogenase maturation protein HydF. (403 aa)
SDN18734.1Iron-only hydrogenase maturation protein HydG. (472 aa)
dltCD-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (81 aa)
SDN24717.1D-alanine--poly(phosphoribitol) ligase subunit 1. (495 aa)
SDN25785.1Pyruvate-ferredoxin/flavodoxin oxidoreductase. (1177 aa)
SDN33185.1Hypothetical protein. (264 aa)
SDN39483.1Propionaldehyde dehydrogenase. (474 aa)
SDN39673.1Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (218 aa)
SDN38786.1Isocitrate dehydrogenase (NAD+). (388 aa)
SDN39916.1Alcohol dehydrogenase. (390 aa)
SDN38813.1Aconitase. (643 aa)
SDN40342.1Predicted Zn-dependent peptidase. (426 aa)
SDN40385.1Predicted Zn-dependent peptidase. (425 aa)
SDN48873.1Branched-chain amino acid aminotransferase. (356 aa)
SDN50969.1DHHW protein. (380 aa)
SDN51009.1Alginate O-acetyltransferase complex protein AlgI; Belongs to the membrane-bound acyltransferase family. (467 aa)
SDN60208.1NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family. (296 aa)
SDN61680.1Iron only hydrogenase large subunit, C-terminal domain. (417 aa)
SDN62003.1Putative phosphotransacetylase; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (190 aa)
SDN64361.1Alpha/beta hydrolase family protein. (250 aa)
SDN66818.1Aminotransferase. (384 aa)
SDN66894.1Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (576 aa)
SDN65904.1Iron complex transport system substrate-binding protein. (346 aa)
SDN69058.1Hypothetical protein. (270 aa)
SDN76128.12-oxoglutarate ferredoxin oxidoreductase, gamma subunit. (177 aa)
SDN76179.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (250 aa)
SDN76227.12-oxoglutarate ferredoxin oxidoreductase subunit alpha. (346 aa)
SDN76266.12-oxoglutarate ferredoxin oxidoreductase subunit delta. (68 aa)
SDN76347.1DRTGG domain-containing protein. (115 aa)
SDN76384.1Anti-sigma regulatory factor (Ser/Thr protein kinase). (140 aa)
SDN76423.1Iron only hydrogenase large subunit, C-terminal domain. (429 aa)
SDN76552.1DRTGG domain-containing protein. (109 aa)
SDN76597.1Hypothetical protein. (241 aa)
SDN82688.13-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
SDN82723.1Enoyl-[acyl-carrier protein] reductase II. (318 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa)
SDN82803.1[acyl-carrier-protein] S-malonyltransferase. (308 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (75 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (267 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (294 aa)
SDN82514.1acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
SDN82556.13-hydroxyacyl-[acyl-carrier-protein] dehydratase. (144 aa)
SDN82595.1acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (148 aa)
SDN82634.13-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
SDN84454.1Alginate O-acetyltransferase complex protein AlgI; Belongs to the membrane-bound acyltransferase family. (471 aa)
SDN84485.1DHHW protein. (502 aa)
SDN90713.1L-2-amino-thiazoline-4-carboxylic acid hydrolase. (161 aa)
SDN93190.1Acetaldehyde dehydrogenase /alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (869 aa)
ilvDDihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (563 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (501 aa)
SDN98681.12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (521 aa)
leuC3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (417 aa)
leuD3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (159 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa)
SDN98374.1Glycine/D-amino acid oxidase. (479 aa)
SDN98517.1Acetolactate synthase, large subunit. (554 aa)
SDN98545.1Acetolactate synthase, small subunit. (166 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa)
SDO01532.1Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
SDO10225.1Oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (378 aa)
Your Current Organism:
Acetanaerobacterium elongatum
NCBI taxonomy Id: 258515
Other names: A. elongatum, AS 1.5012, Acetanaerobacterium elongatum Chen and Dong 2004, JCM 12359, strain Z7
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