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hisZ hisZ Psyc_1152 Psyc_1152 hisC hisC Psyc_1350 Psyc_1350 hisC2 hisC2 hisD hisD hisG hisG hisI hisI hisF hisF hisA hisA hisH hisH hisB hisB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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hisZPossible ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (434 aa)
Psyc_1152Flavin monoamine oxidase related protein; No indication of substrate, could be polyamine oxidase or L-amino acid oxidase. (533 aa)
hisCAminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (380 aa)
Psyc_1350Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
hisC2Histidinol phosphate aminotransferase apoenzyme; One of two hisC genes in the Psychrobacter 273-4 genome; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (377 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (431 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (231 aa)
hisIphosphoribosyl-AMP cyclohydrolase; This orf aligns to domains of both pyrophosphohydrolase and cyclohydrolase functions, suggesting a bifunctional enzyme; In the N-terminal section; belongs to the PRA-CH family. (282 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (260 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (246 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (214 aa)
hisBImidazoleglycerol-phosphate dehydratase; This orf is probably the monofunctional variety of hisB. (221 aa)
Your Current Organism:
Psychrobacter arcticus
NCBI taxonomy Id: 259536
Other names: P. arcticus 273-4, Psychrobacter arcticus 273-4, Psychrobacter arcticus str. 273-4, Psychrobacter arcticus strain 273-4, Psychrobacter sp. 273-4
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