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Mbur_0052 Mbur_0052 Mbur_0100 Mbur_0100 Mbur_0290 Mbur_0290 Mbur_0338 Mbur_0338 Mbur_0367 Mbur_0367 mtaA mtaA Mbur_0470 Mbur_0470 Mbur_0535 Mbur_0535 Mbur_0536 Mbur_0536 Mbur_0537 Mbur_0537 Mbur_0654 Mbur_0654 Mbur_0796 Mbur_0796 Mbur_0808 Mbur_0808 Mbur_0811 Mbur_0811 Mbur_0812 Mbur_0812 Mbur_0813 Mbur_0813 Mbur_0814 Mbur_0814 mtmC mtmC mtmC-2 mtmC-2 sepS sepS mtbC mtbC mtaA-2 mtaA-2 cbiXS cbiXS Mbur_1036 Mbur_1036 Mbur_1037 Mbur_1037 Mbur_1038 Mbur_1038 cbiA/cobB cbiA/cobB mtbC-2 mtbC-2 mttC mttC Mbur_1375 Mbur_1375 Mbur_1440 Mbur_1440 nrpR nrpR hdrC hdrC hdrB hdrB mtrH mtrH mtrG mtrG mtrF mtrF mtrA mtrA mtrB mtrB mtrC mtrC mtrD mtrD mtrE mtrE Mbur_1651 Mbur_1651 Mbur_1657 Mbur_1657 Mbur_1658 Mbur_1658 Mbur_1802 Mbur_1802 Mbur_1902 Mbur_1902 Mbur_1903 Mbur_1903 Mbur_1904 Mbur_1904 Mbur_1905 Mbur_1905 Mbur_1906 Mbur_1906 Mbur_1907 Mbur_1907 Mbur_1908 Mbur_1908 Mbur_1909 Mbur_1909 Mbur_1971 Mbur_1971 Mbur_2069 Mbur_2069 Mbur_2070 Mbur_2070 mtbA-2 mtbA-2 Mbur_2130 Mbur_2130 Mbur_2243 Mbur_2243 Mbur_2244 Mbur_2244 mtbC-3 mtbC-3 mttB-2 mttB-2 mttC-2 mttC-2 mttB mttB mcrA mcrA mcrG mcrG mcrC mcrC mcrD mcrD mcrB mcrB Mbur_2422 Mbur_2422 Mbur_2436 Mbur_2436 Mbur_2437 Mbur_2437
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mbur_0052Hypothetical protein; Evidence code ER5. (309 aa)
Mbur_0100Protein of unknown function UCP006557; Evidence code ER4. (130 aa)
Mbur_0290Lambda repressor-like DNA binding-domain protein; Evidence code ER4. (107 aa)
Mbur_0338Protein of unknown function UCP004929; Evidence code ER4. (282 aa)
Mbur_0367Formaldehyde-activating enzyme, tetrahydromethanopterin-dependent; Evidence code ER2. (160 aa)
mtaAMethanol-specific methylcobalamin:CoM methyltransferase; Evidence code ER2. (310 aa)
Mbur_0470Protein with two cysteine-rich domains; Evidence code ER4. (361 aa)
Mbur_0535DDE superfamily, IS4 transposase; Evidence code ER4. (373 aa)
Mbur_0536Protein with DUF1743 domain; Evidence code ER4. (302 aa)
Mbur_0537Protein with C-terminal TPP-binding region; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (511 aa)
Mbur_0654Protein of unknown function UCP004962; Evidence code ER4. (157 aa)
Mbur_0796Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (459 aa)
Mbur_0808Methanol-specific methylcobalamin:CoM methyltransferase; Evidence code ER2. (338 aa)
Mbur_0811Methanol corrinoid protein; Evidence code ER2. (254 aa)
Mbur_0812Methanol--corrinoid methyltransferase; Evidence code ER2. (462 aa)
Mbur_0813Methanol corrinoid protein; Evidence code ER2. (256 aa)
Mbur_0814Methanol--corrinoid methyltransferase; Evidence code ER2. (461 aa)
mtmCMonomethylamine corrinoid protein; Evidence code ER2. (217 aa)
mtmC-2Monomethylamine corrinoid protein; Evidence code ER2. (217 aa)
sepSO-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa)
mtbCDimethylamine corrinoid protein; Evidence code ER3. (214 aa)
mtaA-2Methanol-specific methylcobalamin:CoM methyltransferase; Evidence code ER2. (345 aa)
cbiXSSirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (131 aa)
Mbur_1036Protein containing Mur ligase middle domain-like central region; Evidence code ER4. (454 aa)
Mbur_1037Protein containing oxidoreductase/nitrogenase, component 1-like domain; Evidence code ER4. (370 aa)
Mbur_1038Nitrogenase iron protein; Evidence code ER2. (264 aa)
cbiA/cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (489 aa)
mtbC-2Dimethylamine corrinoid protein; Evidence code ER2. (251 aa)
mttCTrimethylamine corrinoid protein; Evidence code ER2. (216 aa)
Mbur_1375Archaeal histone A; Evidence code ER2. (73 aa)
Mbur_1440Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (387 aa)
nrpRTranscriptional regulator of nitrogen assimilation; Evidence code ER2; C2-type. (252 aa)
hdrCCoB--CoM heterodisulfide reductase iron-sulfur subunit C; Evidence code ER2. (164 aa)
hdrBCoB--CoM heterodisulfide reductase subunit B; Evidence code ER2. (306 aa)
mtrHTetrahydromethanopterin S-methyltransferase subunit H; Evidence code ER2. (318 aa)
mtrGTetrahydromethanopterin S-methyltransferase subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (75 aa)
mtrFTetrahydromethanopterin S-methyltransferase subunit F; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (79 aa)
mtrATetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (241 aa)
mtrBTetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (107 aa)
mtrCTetrahydromethanopterin S-methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (269 aa)
mtrDTetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (239 aa)
mtrETetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrE family. (301 aa)
Mbur_1651Protein with two ABC transporter ATPase domains; Evidence code ER4. (573 aa)
Mbur_1657Pyridoxamine 5'-phosphate oxidase-related, FMN-binding; Evidence code ER4. (134 aa)
Mbur_1658Transcriptional regulator, ArsR family protein; Evidence code ER4. (253 aa)
Mbur_1802AIR synthase related protein; Evidence code ER4. (440 aa)
Mbur_1902Methylcoenzyme M reductase system component A2; Evidence code ER2. (538 aa)
Mbur_1903Protein of unknown function UPF0288; Evidence code ER4; Belongs to the UPF0288 family. (521 aa)
Mbur_1904Protein of unknown function UCP005642; Evidence code ER4. (144 aa)
Mbur_1905Protein of unknown function UCP018781; Evidence code ER4. (151 aa)
Mbur_19062-hydroxyglutaryl-CoA dehydratase component A; Evidence code ER3. (414 aa)
Mbur_1907Hypothetical protein; Evidence code ER5. (197 aa)
Mbur_1908Protein of unknown function UCP019164; Evidence code ER4. (310 aa)
Mbur_1909Carboxymuconolactone decarboxylase-domain protein; Evidence code ER4. (149 aa)
Mbur_1971Protein of unknown function DUF167; Evidence code ER4; Belongs to the UPF0235 family. (107 aa)
Mbur_2069Protein of unknown function UPF0142; Evidence code ER4. (426 aa)
Mbur_2070Hypothetical protein; Evidence code ER5. (214 aa)
mtbA-2Methylamine-specific methylcobamide:CoM methyltransferase; Evidence code ER2. (344 aa)
Mbur_2130Helix-turn-helix 3-containing transcriptional regulator, XRE family; Evidence code ER4; HTH3. (167 aa)
Mbur_2243Methyltransferase MtxX; Evidence code ER4. (285 aa)
Mbur_2244Fusion of Tetrahydromethanopterin S-methyltransferase subunits A and H; Evidence code ER3. (453 aa)
mtbC-3Dimethylamine corrinoid protein; Evidence code ER2. (168 aa)
mttB-2Trimethylamine methyltransferase; Catalyzes the transfer of a methyl group from trimethylamine to the corrinoid cofactor of MttC. (497 aa)
mttC-2Trimethylamine corrinoid protein; Evidence code ER2. (216 aa)
mttBTrimethylamine methyltransferase; Evidence code ER3; Belongs to the trimethylamine methyltransferase family. (484 aa)
mcrAMethyl-coenzyme M reductase, subunit alpha; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (572 aa)
mcrGMethyl-coenzyme M reductase, subunit gamma; Evidence code ER2. (248 aa)
mcrCHighly conserved methyl-coenzyme M reductase operon protein C with unknown function; Evidence code ER4. (200 aa)
mcrDConserved methyl-coenzyme M reductase operon protein D with unknown function; Evidence code ER4. (162 aa)
mcrBMethyl-coenzyme M reductase, subunit beta; Evidence code ER2. (434 aa)
Mbur_2422Radical SAM protein with DUF512 domain; Evidence code ER4. (409 aa)
Mbur_2436CoB-CoM heterodisulfide reductase, subunit E; Evidence code ER2. (268 aa)
Mbur_2437CoB-CoM heterodisulfide reductase, subunit D; Evidence code ER2. (415 aa)
Your Current Organism:
Methanococcoides burtonii
NCBI taxonomy Id: 259564
Other names: M. burtonii DSM 6242, Methanococcoides burtonii DSM 6242, Methanococcoides burtonii str. DSM 6242
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