STRINGSTRING
AEI99989.1 AEI99989.1 AEJ00036.1 AEJ00036.1 AEJ00057.1 AEJ00057.1 AEJ00071.1 AEJ00071.1 AEJ00072.1 AEJ00072.1 AEJ00118.1 AEJ00118.1 AEJ00440.1 AEJ00440.1 AEJ00474.1 AEJ00474.1 AEJ00485.1 AEJ00485.1 AEJ00606.1 AEJ00606.1 AEJ00613.1 AEJ00613.1 AEJ00719.1 AEJ00719.1 AEJ00721.1 AEJ00721.1 AEJ00725.1 AEJ00725.1 AEJ00766.1 AEJ00766.1 lptA lptA AEJ00768.1 AEJ00768.1 AEJ00808.1 AEJ00808.1 AEJ00809.1 AEJ00809.1 AEJ00810.1 AEJ00810.1 AEJ00811.1 AEJ00811.1 AEJ00812.1 AEJ00812.1 AEJ00829.1 AEJ00829.1 AEJ00830.1 AEJ00830.1 AEJ00913.1 AEJ00913.1 AEJ00989.1 AEJ00989.1 apaH apaH bamE bamE AEJ01345.1 AEJ01345.1 AEJ01346.1 AEJ01346.1 AEJ01348.1 AEJ01348.1 AEJ01592.1 AEJ01592.1 AEJ01593.1 AEJ01593.1 AEJ01594.1 AEJ01594.1 AEJ01596.1 AEJ01596.1 AEJ01685.1 AEJ01685.1 AEJ01688.1 AEJ01688.1 surA surA lptD lptD AEJ01821.1 AEJ01821.1 ftsB ftsB bamB bamB AEJ01947.1 AEJ01947.1 AEJ02006.1 AEJ02006.1 AEJ02026.1 AEJ02026.1 AEJ02027.1 AEJ02027.1 AEJ02035.1 AEJ02035.1 AEJ02039.1 AEJ02039.1 AEJ02040.1 AEJ02040.1 mnmA mnmA nudJ nudJ AEJ02107.1 AEJ02107.1 AEJ02143.1 AEJ02143.1 AEJ02144.1 AEJ02144.1 AEJ02337.1 AEJ02337.1 AEJ02372.1 AEJ02372.1 AEJ02378.1 AEJ02378.1 AEJ02385.1 AEJ02385.1 AEJ02386.1 AEJ02386.1 AEJ02387.1 AEJ02387.1 AEJ02388.1 AEJ02388.1 AEJ02389.1 AEJ02389.1 mutM mutM AEJ02392.1 AEJ02392.1 AEJ02393.1 AEJ02393.1 AEJ02394.1 AEJ02394.1 AEJ02395.1 AEJ02395.1 AEJ02399.1 AEJ02399.1 AEJ02439.1 AEJ02439.1 AEJ02440.1 AEJ02440.1 AEJ02463.1 AEJ02463.1 lptE lptE AEJ02489.1 AEJ02489.1 dsbB dsbB AEJ02718.1 AEJ02718.1 AEJ02719.1 AEJ02719.1 AEJ02720.1 AEJ02720.1 AEJ02730.1 AEJ02730.1 AEJ02731.1 AEJ02731.1 bamD bamD AEJ02851.1 AEJ02851.1 AEJ02852.1 AEJ02852.1 AEJ02908.1 AEJ02908.1 AEJ02951.1 AEJ02951.1 AEJ02952.1 AEJ02952.1 cca cca AEJ03047.1 AEJ03047.1 aat aat bpt bpt AEJ03154.1 AEJ03154.1 AEJ03156.1 AEJ03156.1 AEJ03163.1 AEJ03163.1 AEJ03164.1 AEJ03164.1 AEJ03165.1 AEJ03165.1 AEJ03166.1 AEJ03166.1 AEJ03167.1 AEJ03167.1 glyS glyS glyQ glyQ lnt lnt AEJ03171.1 AEJ03171.1 minC minC AEJ03173.1 AEJ03173.1 minE minE lolB lolB bamA bamA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEI99989.1PFAM: Fatty acid desaturase, type 1; KEGG: net:Neut_0779 fatty acid desaturase. (396 aa)
AEJ00036.1HemY domain protein; PFAM: HemY, N-terminal; KEGG: nit:NAL212_0446 HemY domain-containing protein. (391 aa)
AEJ00057.1PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; KEGG: nit:NAL212_0654 2,3-bisphosphoglycerate-independent phosphoglycerate mutase. (347 aa)
AEJ00071.1KEGG: nit:NAL212_2905 two component transcriptional regulator, Fis family; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region. (186 aa)
AEJ00072.1KEGG: nit:NAL212_2904 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region. (419 aa)
AEJ00118.1Disulfide bond isomerase, DsbC/G; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (240 aa)
AEJ00440.1PFAM: Arsenate reductase-like; KEGG: nit:NAL212_0748 arsenate reductase like protein; Belongs to the ArsC family. (114 aa)
AEJ00474.1PFAM: Peptidase S49; KEGG: nit:NAL212_0775 peptidase S49. (314 aa)
AEJ00485.1PFAM: NlpBDapX lipoprotein; KEGG: nit:NAL212_2098 putative transmembrane protein. (385 aa)
AEJ00606.1PEP motif putative anchor domain protein; KEGG: meh:M301_2279 protein of unknown function DUF1555; TIGRFAM: PEP-CTERM anchor; PFAM: PEP-CTERM bacterial. (175 aa)
AEJ00613.1KEGG: nit:NAL212_0951 hypothetical protein. (116 aa)
AEJ00719.1KEGG: nit:NAL212_1786 hypothetical protein. (64 aa)
AEJ00721.1PFAM: Protein of unknown function DUF339; KEGG: nit:NAL212_1784 hypothetical protein. (77 aa)
AEJ00725.1Protein of unknown function DUF1555; PFAM: PEP-CTERM bacterial; KEGG: cps:CPS_4565 hypothetical protein. (170 aa)
AEJ00766.1PFAM: Protein of unknown function DUF1239; KEGG: nit:NAL212_2117 hypothetical protein. (188 aa)
lptALipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (176 aa)
AEJ00768.1ABC transporter related protein; KEGG: nit:NAL212_2115 sulfate-transporting ATPase; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core. (240 aa)
AEJ00808.1PFAM: Protein of unknown function DUF526; KEGG: nit:NAL212_1205 hypothetical protein. (102 aa)
AEJ00809.1PFAM: Aminoglycoside phosphotransferase; KEGG: nit:NAL212_1206 aminoglycoside phosphotransferase. (334 aa)
AEJ00810.1PFAM: Nucleotidyl transferase; KEGG: nit:NAL212_1207 nucleotidyl transferase. (232 aa)
AEJ00811.1PFAM: Peptidase M24, structural domain; Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal; KEGG: nit:NAL212_1208 peptidase M24. (435 aa)
AEJ00812.1KEGG: nit:NAL212_1209 hypothetical protein. (123 aa)
AEJ00829.1Manually curated; PFAM: ABC transporter-like; KEGG: nit:NAL212_2655 ABC transporter-like protein; SMART: ATPase, AAA+ type, core. (534 aa)
AEJ00830.1Hypothetical protein. (149 aa)
AEJ00913.1PFAM: Protein of unknown function DUF185; KEGG: nit:NAL212_0818 hypothetical protein. (395 aa)
AEJ00989.1KEGG: nit:NAL212_2623 peptidase S16 lon domain-containing protein. (831 aa)
apaHBis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (267 aa)
bamESmpA/OmlA domain-containing protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (137 aa)
AEJ01345.1KEGG: nit:NAL212_1338 PEP motif putative anchor domain-containing protein; TIGRFAM: PEP-CTERM anchor; PFAM: PEP-CTERM bacterial. (177 aa)
AEJ01346.1PFAM: Type IV pilus assembly PilZ. (88 aa)
AEJ01348.1PFAM: Permease YjgP/YjgQ, predicted; KEGG: nit:NAL212_2669 permease YjgP/YjgQ family protein. (359 aa)
AEJ01592.1KEGG: nit:NAL212_0962 PEP motif putative anchor domain-containing protein; TIGRFAM: PEP-CTERM anchor; PFAM: PEP-CTERM bacterial. (353 aa)
AEJ01593.1Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (255 aa)
AEJ01594.1KEGG: nit:NAL212_1085 hypothetical protein. (125 aa)
AEJ01596.1ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (362 aa)
AEJ01685.1KEGG: nit:NAL212_0854 hypothetical protein. (67 aa)
AEJ01688.1PFAM: Peptidase M48, Ste24p; KEGG: nit:NAL212_0851 peptidase M48 Ste24p. (503 aa)
surAChaperone surA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (440 aa)
lptDLPS-assembly protein lptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (744 aa)
AEJ01821.1PFAM: Globin, truncated bacterial-like; KEGG: nit:NAL212_2228 globin. (134 aa)
ftsBCell division protein ftsB-like protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (97 aa)
bamBOuter membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (379 aa)
AEJ01947.1PFAM: Protein of unknown function DUF2133; KEGG: nit:NAL212_1229 hypothetical protein. (212 aa)
AEJ02006.1PFAM: Protein of unknown function DUF498; KEGG: nit:NAL212_1746 hypothetical protein. (122 aa)
AEJ02026.1PFAM: Peroxiredoxin, OsmC-like protein; KEGG: nit:NAL212_2330 OsmC family protein. (138 aa)
AEJ02027.1PFAM: Cytochrome c, class I; KEGG: nit:NAL212_2331 cytochrome c class I. (103 aa)
AEJ02035.1PFAM: Protein of unknown function DUF971; KEGG: nit:NAL212_2337 hypothetical protein. (136 aa)
AEJ02039.1Hypothetical protein. (36 aa)
AEJ02040.1KEGG: gvi:gll1319 hypothetical protein. (420 aa)
mnmAtRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (359 aa)
nudJPFAM: NUDIX hydrolase domain; KEGG: nit:NAL212_2548 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. (151 aa)
AEJ02107.1KEGG: nit:NAL212_2392 nitrite reductase, copper-containing; TIGRFAM: Nitrite reductase, copper containing; PFAM: Multicopper oxidase, type 1; Multicopper oxidase, type 3; Belongs to the multicopper oxidase family. (365 aa)
AEJ02143.1Protein rnfH; KEGG: nit:NAL212_1986 hypothetical protein; HAMAP: Protein rnfH; PFAM: Uncharacterised protein family UPF0125; Belongs to the UPF0125 (RnfH) family. (100 aa)
AEJ02144.1Cyclase/dehydrase; PFAM: Streptomyces cyclase/dehydrase; KEGG: nit:NAL212_1987 cyclase/dehydrase. (145 aa)
AEJ02337.1PEP motif putative anchor domain protein; KEGG: meh:M301_2279 protein of unknown function DUF1555; TIGRFAM: PEP-CTERM anchor; PFAM: PEP-CTERM bacterial. (179 aa)
AEJ02372.1PFAM: DSBA oxidoreductase; KEGG: nit:NAL212_1353 DsbA oxidoreductase. (212 aa)
AEJ02378.1PFAM: Cytochrome c assembly protein; KEGG: nit:NAL212_1457 cytochrome c assembly protein. (319 aa)
AEJ02385.1PFAM: Fatty acid desaturase, type 1; KEGG: nit:NAL212_1449 fatty acid desaturase. (396 aa)
AEJ02386.1KEGG: nit:NAL212_1448 pseudouridine synthase Rsu; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; Belongs to the pseudouridine synthase RsuA family. (185 aa)
AEJ02387.1PFAM: Phosphoglycerate mutase; KEGG: nit:NAL212_1447 putative phosphohistidine phosphatase, SixA. (150 aa)
AEJ02388.1UPF0235 protein yggU; TIGRFAM: Conserved hypothetical protein CHP00251; HAMAP: Protein of unknown function DUF167; KEGG: nit:NAL212_1446 hypothetical protein; PFAM: Protein of unknown function DUF167; Belongs to the UPF0235 family. (98 aa)
AEJ02389.1PFAM: Protein of unknown function YGGT; KEGG: nit:NAL212_1445 hypothetical protein. (191 aa)
mutMFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (276 aa)
AEJ02392.1Hypothetical protein; Manually curated; KEGG: nit:NAL212_1442 hypothetical protein. (290 aa)
AEJ02393.1PFAM: ABC-type uncharacterised transport system; KEGG: nit:NAL212_1441 ABC transporter. (452 aa)
AEJ02394.1KEGG: nit:NAL212_1440 putative ABC-2 type transport system permease protein. (247 aa)
AEJ02395.1KEGG: nit:NAL212_1439 ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core. (242 aa)
AEJ02399.1KEGG: nit:NAL212_1435 phosphoglycolate phosphatase; TIGRFAM: 2-phosphoglycolate phosphatase, prokaryotic; HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. (215 aa)
AEJ02439.1KEGG: nit:NAL212_0951 hypothetical protein. (135 aa)
AEJ02440.1Hypothetical protein. (77 aa)
AEJ02463.1KEGG: nmu:Nmul_A0025 TraR/DksA family transcriptional regulator. (132 aa)
lptERare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. (166 aa)
AEJ02489.1MJ0042 family finger-like protein; TIGRFAM: Zinc finger/thioredoxin putative; KEGG: nit:NAL212_0385 hypothetical protein. (271 aa)
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (157 aa)
AEJ02718.1KEGG: nit:NAL212_2862 E3 ubiquitin ligase. (309 aa)
AEJ02719.1LemA family protein; PFAM: LemA; KEGG: nit:NAL212_2863 LemA family protein. (190 aa)
AEJ02720.1KEGG: nit:NAL212_2864 hypothetical protein. (123 aa)
AEJ02730.1KEGG: nit:NAL212_1992 ArsC family protein; TIGRFAM: Conserved hypothetical protein, ArsC related; PFAM: Arsenate reductase-like; Belongs to the ArsC family. (117 aa)
AEJ02731.1PFAM: Cupin 2, conserved barrel; KEGG: nit:NAL212_1993 cupin 2 barrel domain-containing protein. (112 aa)
bamDOuter membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (258 aa)
AEJ02851.1PFAM: Stringent starvation protein B; KEGG: nit:NAL212_2477 stringent starvation protein B. (142 aa)
AEJ02852.1PFAM: Glutathione S-transferase, N-terminal; KEGG: nit:NAL212_2478 glutathione S-transferase domain. (199 aa)
AEJ02908.1PFAM: Major facilitator superfamily MFS-1; KEGG: nit:NAL212_0697 major facilitator superfamily MFS_1. (452 aa)
AEJ02951.1PFAM: Permease YjgP/YjgQ, predicted; KEGG: nit:NAL212_2669 permease YjgP/YjgQ family protein. (358 aa)
AEJ02952.1PFAM: Permease YjgP/YjgQ, predicted; KEGG: nit:NAL212_2670 permease YjgP/YjgQ family protein. (353 aa)
ccaPolynucleotide adenylyltransferase/metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (410 aa)
AEJ03047.1PFAM: Lytic transglycosylase-like, catalytic; KEGG: nit:NAL212_0190 lytic transglycosylase catalytic. (638 aa)
aatLeucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. (232 aa)
bptarginyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. (235 aa)
AEJ03154.1Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (227 aa)
AEJ03156.1PFAM: Protein of unknown function DUF1841; KEGG: nit:NAL212_0200 hypothetical protein. (145 aa)
AEJ03163.1KEGG: nwa:Nwat_2429 hypothetical protein. (77 aa)
AEJ03164.1KEGG: yps:YPTB1833 hypothetical protein. (137 aa)
AEJ03165.1PFAM: Protein of unknown function DUF45; KEGG: nit:NAL212_3099 hypothetical protein. (233 aa)
AEJ03166.1KEGG: nit:NAL212_3100 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase. (246 aa)
AEJ03167.1KEGG: nit:NAL212_3101 histidinol-phosphate phosphatase family protein; TIGRFAM: Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; PFAM: Haloacid dehalogenase-like hydrolase. (179 aa)
glySTIGRFAM: Glycyl-tRNA synthetase, class IIc, beta subunit; HAMAP: Glycyl-tRNA synthetase beta subunit; KEGG: nit:NAL212_3102 glycyl-tRNA synthetase, beta subunit. (729 aa)
glyQTIGRFAM: Glycyl-tRNA synthetase, class IIc, alpha subunit; HAMAP: Glycyl-tRNA synthetase, class IIc, alpha subunit; KEGG: nit:NAL212_3103 glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase, class IIc, alpha subunit. (307 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (503 aa)
AEJ03171.1PFAM: Tetratricopeptide TPR-1; KEGG: nit:NAL212_3105 hypothetical protein. (578 aa)
minCSeptum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (249 aa)
AEJ03173.1KEGG: nit:NAL212_3107 septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase. (270 aa)
minECell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (92 aa)
lolBOuter-membrane lipoprotein lolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (234 aa)
bamAOuter membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (757 aa)
Your Current Organism:
Nitrosomonas sp. Is79A3
NCBI taxonomy Id: 261292
Other names: N. sp. Is79A3
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