STRINGSTRING
rpsG rpsG rplB rplB rpsS rpsS rplV rplV rplN rplN rpsE rpsE rpmD rpmD rplO rplO secY secY rpsD rpsD rpoA rpoA bioC bioC AEJ02492.1 AEJ02492.1 AEJ02491.1 AEJ02491.1 AEJ02483.1 AEJ02483.1 AEJ02446.1 AEJ02446.1 AEJ02442.1 AEJ02442.1 AEJ02430.1 AEJ02430.1 AEJ02411.1 AEJ02411.1 AEJ02406.1 AEJ02406.1 AEJ02405.1 AEJ02405.1 AEJ02396.1 AEJ02396.1 AEJ02381.1 AEJ02381.1 ffh ffh rpoZ rpoZ AEJ02353.1 AEJ02353.1 AEJ02339.1 AEJ02339.1 AEJ02321.1 AEJ02321.1 AEJ02317.1 AEJ02317.1 AEJ02316.1 AEJ02316.1 AEJ02311.1 AEJ02311.1 AEJ02299.1 AEJ02299.1 AEJ02263.1 AEJ02263.1 AEJ00318.1 AEJ00318.1 AEJ00324.1 AEJ00324.1 AEJ00352.1 AEJ00352.1 AEJ00377.1 AEJ00377.1 AEJ00465.1 AEJ00465.1 accA accA carA carA AEJ00503.1 AEJ00503.1 gpsA gpsA AEJ00530.1 AEJ00530.1 AEJ00531.1 AEJ00531.1 AEJ00533.1 AEJ00533.1 AEJ00544.1 AEJ00544.1 AEJ00573.1 AEJ00573.1 AEJ00582.1 AEJ00582.1 AEJ00587.1 AEJ00587.1 AEJ00596.1 AEJ00596.1 AEJ00608.1 AEJ00608.1 AEJ00660.1 AEJ00660.1 rplA rplA rpoB rpoB rpoC rpoC AEJ00723.1 AEJ00723.1 AEJ00724.1 AEJ00724.1 potA potA gatA gatA AEJ00768.1 AEJ00768.1 AEJ00769.1 AEJ00769.1 AEJ00770.1 AEJ00770.1 AEJ00797.1 AEJ00797.1 trmB trmB AEJ00816.1 AEJ00816.1 cysA cysA AEJ00879.1 AEJ00879.1 tatC tatC tatB tatB tatA tatA AEJ00912.1 AEJ00912.1 xseA xseA AEJ00938.1 AEJ00938.1 AEJ00948.1 AEJ00948.1 AEJ00961.1 AEJ00961.1 AEJ00997.1 AEJ00997.1 AEJ01029.1 AEJ01029.1 AEJ01037.1 AEJ01037.1 AEJ01040.1 AEJ01040.1 AEJ01059.1 AEJ01059.1 gcvH gcvH gcvPA gcvPA gcvPB gcvPB AEJ01092.1 AEJ01092.1 AEJ01132.1 AEJ01132.1 AEJ01185.1 AEJ01185.1 AEJ01226.1 AEJ01226.1 AEJ00288.1 AEJ00288.1 ruvB ruvB ruvA ruvA atpC atpC atpD-2 atpD-2 atpG atpG atpA-2 atpA-2 atpH atpH atpF-2 atpF-2 atpE-2 atpE-2 atpB-2 atpB-2 ftsE ftsE AEJ00228.1 AEJ00228.1 AEJ00199.1 AEJ00199.1 AEJ00170.1 AEJ00170.1 dnaG dnaG AEJ00156.1 AEJ00156.1 AEJ00137.1 AEJ00137.1 AEJ00124.1 AEJ00124.1 AEJ00117.1 AEJ00117.1 AEJ00111.1 AEJ00111.1 AEJ00110.1 AEJ00110.1 mfd mfd AEJ00092.1 AEJ00092.1 AEJ00091.1 AEJ00091.1 AEJ00081.1 AEJ00081.1 AEJ00076.1 AEJ00076.1 ribH ribH AEJ00028.1 AEJ00028.1 AEJ00022.1 AEJ00022.1 AEJ00020.1 AEJ00020.1 sucD sucD AEJ00010.1 AEJ00010.1 AEI99967.1 AEI99967.1 AEI99954.1 AEI99954.1 atpA atpA atpF atpF atpE atpE atpB atpB AEI99947.1 AEI99947.1 atpD atpD AEI99920.1 AEI99920.1 AEI99910.1 AEI99910.1 leuC leuC leuD leuD accD accD AEJ02231.1 AEJ02231.1 AEJ02135.1 AEJ02135.1 AEJ02126.1 AEJ02126.1 AEJ02125.1 AEJ02125.1 AEJ02120.1 AEJ02120.1 AEJ02091.1 AEJ02091.1 AEJ02076.1 AEJ02076.1 ubiE ubiE AEJ02034.1 AEJ02034.1 AEJ01990.1 AEJ01990.1 AEJ01988.1 AEJ01988.1 hypA hypA uvrC uvrC priA priA AEJ01930.1 AEJ01930.1 AEJ01919.1 AEJ01919.1 AEJ01909.1 AEJ01909.1 AEJ01908.1 AEJ01908.1 AEJ01905.1 AEJ01905.1 fumC fumC AEJ01891.1 AEJ01891.1 AEJ01890.1 AEJ01890.1 eno eno recG recG AEJ01839.1 AEJ01839.1 AEJ01837.1 AEJ01837.1 AEJ01826.1 AEJ01826.1 AEJ01811.1 AEJ01811.1 AEJ01810.1 AEJ01810.1 AEJ01809.1 AEJ01809.1 AEJ01797.1 AEJ01797.1 AEJ01795.1 AEJ01795.1 uvrB uvrB AEJ01771.1 AEJ01771.1 clpX clpX AEJ01705.1 AEJ01705.1 AEJ01704.1 AEJ01704.1 AEJ01683.1 AEJ01683.1 AEJ01668.1 AEJ01668.1 AEJ01617.1 AEJ01617.1 dcd dcd cysD cysD cysC cysC AEJ01562.1 AEJ01562.1 AEJ01555.1 AEJ01555.1 dnaX dnaX sucD-2 sucD-2 AEJ01490.1 AEJ01490.1 AEJ01477.1 AEJ01477.1 AEJ01456.1 AEJ01456.1 AEJ01432.1 AEJ01432.1 AEJ01429.1 AEJ01429.1 hslU hslU hslV hslV AEJ01412.1 AEJ01412.1 AEJ01392.1 AEJ01392.1 AEJ01382.1 AEJ01382.1 parC parC AEJ01348.1 AEJ01348.1 AEJ01317.1 AEJ01317.1 AEJ01301.1 AEJ01301.1 AEJ01300.1 AEJ01300.1 rnpA rnpA AEJ03247.1 AEJ03247.1 AEJ03243.1 AEJ03243.1 AEJ03215.1 AEJ03215.1 dxr dxr rpsB rpsB AEJ03135.1 AEJ03135.1 AEJ03130.1 AEJ03130.1 AEJ03112.1 AEJ03112.1 AEJ03109.1 AEJ03109.1 cysN cysN AEJ03099.1 AEJ03099.1 AEJ03096.1 AEJ03096.1 AEJ03084.1 AEJ03084.1 AEJ03083.1 AEJ03083.1 AEJ03036.1 AEJ03036.1 AEJ03035.1 AEJ03035.1 AEJ03029.1 AEJ03029.1 AEJ00309.1 AEJ00309.1 AEJ03010.1 AEJ03010.1 AEJ02995.1 AEJ02995.1 AEJ02979.1 AEJ02979.1 ilvA ilvA mutL mutL AEJ02952.1 AEJ02952.1 AEJ02951.1 AEJ02951.1 xseB xseB AEJ02919.1 AEJ02919.1 AEJ02913.1 AEJ02913.1 uvrA uvrA AEJ02898.1 AEJ02898.1 AEJ02890.1 AEJ02890.1 rpmF rpmF AEJ02854.1 AEJ02854.1 AEJ02841.1 AEJ02841.1 AEJ02838.1 AEJ02838.1 priB priB AEJ02833.1 AEJ02833.1 bamD bamD AEJ02808.1 AEJ02808.1 glgC glgC ppk ppk AEJ02726.1 AEJ02726.1 AEJ02710.1 AEJ02710.1 AEJ02680.1 AEJ02680.1 AEJ02679.1 AEJ02679.1 AEJ02678.1 AEJ02678.1 AEJ02672.1 AEJ02672.1 rtcB rtcB AEJ02657.1 AEJ02657.1 cobQ cobQ AEJ02625.1 AEJ02625.1 gyrA gyrA rpsL rpsL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (277 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa)
rplVRibosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (115 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsERibosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (180 aa)
rpmDKEGG: dia:Dtpsy_0391 50S ribosomal protein L30; TIGRFAM: Ribosomal protein L30, bacterial-type; PFAM: Ribosomal protein L30p/L7e, conserved region. (62 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (143 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (443 aa)
rpsDRibosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (223 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (334 aa)
bioCBiotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (293 aa)
AEJ02492.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (160 aa)
AEJ02491.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
AEJ02483.1KEGG: nit:NAL212_0259 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta. (346 aa)
AEJ02446.1PFAM: Methyltransferase type 11; KEGG: nit:NAL212_0155 methyltransferase type 11. (184 aa)
AEJ02442.1PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: nit:NAL212_2526 peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S24 family. (201 aa)
AEJ02430.1KEGG: neu:NE2568 ArsR family regulatory protein; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR. (135 aa)
AEJ02411.1PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; KEGG: nit:NAL212_0932 pyruvate dehydrogenase (cytochrome). (576 aa)
AEJ02406.1Transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; KEGG: neu:NE1587 helix-hairpin-helix DNA-binding motif-containing protein. (124 aa)
AEJ02405.1PFAM: Protein of unknown function DUF2136; KEGG: nit:NAL212_1429 hypothetical protein. (100 aa)
AEJ02396.1PFAM: Outer membrane protein, OmpA/MotB, C-terminal; KEGG: nit:NAL212_1438 OmpA/MotB domain-containing protein. (229 aa)
AEJ02381.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (449 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (68 aa)
AEJ02353.1KEGG: nit:NAL212_1247 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region. (228 aa)
AEJ02339.1KEGG: nit:NAL212_1531 hypothetical protein. (899 aa)
AEJ02321.1KEGG: nde:NIDE1370 hypothetical protein. (387 aa)
AEJ02317.1PFAM: BolA-like protein; KEGG: nit:NAL212_2570 BolA family protein; Belongs to the BolA/IbaG family. (80 aa)
AEJ02316.1PFAM: ABC-2 type transporter; KEGG: nit:NAL212_2571 ABC-2 type transporter. (251 aa)
AEJ02311.1Protein of unknown function DUF140; KEGG: nit:NAL212_2576 hypothetical protein; TIGRFAM: Protein of unknown function DUF140; PFAM: Protein of unknown function DUF140. (265 aa)
AEJ02299.1KEGG: nit:NAL212_2002 succinate dehydrogenase, cytochrome b556 subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit; PFAM: Succinate dehydrogenase, cytochrome b subunit. (129 aa)
AEJ02263.1PFAM: Helix-turn-helix, HxlR type; KEGG: nit:NAL212_0964 transcriptional regulator, HxlR family. (119 aa)
AEJ00318.1ABC-2 type transporter; KEGG: pol:Bpro_4002 hypothetical protein; manually curated; PFAM: ABC-2 type transporter. (276 aa)
AEJ00324.1Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (570 aa)
AEJ00352.1KEGG: nit:NAL212_2613 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region. (128 aa)
AEJ00377.1TIGRFAM: Flagellar protein export ATPase, FliI; ATPase, type III secretion system, FliI/YscN; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; KEGG: nit:NAL212_0483 flagellar protein export ATPase FliI; SMART: ATPase, AAA+ type, core. (468 aa)
AEJ00465.1KEGG: gca:Galf_2014 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region. (234 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (322 aa)
carAKEGG: nit:NAL212_2073 carbamoyl-phosphate synthase, small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family. (384 aa)
AEJ00503.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (473 aa)
gpsAKEGG: nit:NAL212_2153 NAD-dependent glycerol-3-phosphate dehydrogenase domain-containing protein; HAMAP: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal; NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (330 aa)
AEJ00530.1PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: nit:NAL212_2150 enoyl-(acyl-carrier-protein) reductase (NADH). (261 aa)
AEJ00531.1ABC-type transporter, periplasmic subunit; PFAM: Bacterial extracellular solute-binding protein, family 5; KEGG: nit:NAL212_2149 ABC-type transporter, periplasmic subunit. (725 aa)
AEJ00533.1CoA-binding domain protein; PFAM: CoA-binding; GCN5-related N-acetyltransferase; KEGG: gca:Galf_1381 CoA-binding domain-containing protein. (892 aa)
AEJ00544.1KEGG: nit:NAL212_0207 allophanate hydrolase; TIGRFAM: Allophanate hydrolase; PFAM: Amidase. (605 aa)
AEJ00573.1PFAM: Protein of unknown function DUF86; KEGG: pph:Ppha_1588 protein of unknown function DUF86. (138 aa)
AEJ00582.1KEGG: nit:NAL212_1757 MgsA AAA+ ATPase domain-containing protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core. (444 aa)
AEJ00587.1KEGG: nit:NAL212_1752 TonB family protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein. (231 aa)
AEJ00596.1Sigma54 specific transcriptional regulator with PAS/PAC sensor, Fis family; TIGRFAM: PAS; PFAM: RNA polymerase sigma factor 54, interaction; PAS fold; Helix-turn-helix, Fis-type; KEGG: azc:AZC_0759 transcriptional regulator; SMART: ATPase, AAA+ type, core; PAS. (609 aa)
AEJ00608.1Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: nit:NAL212_0843 metal dependent phosphohydrolase. (323 aa)
AEJ00660.1KEGG: nit:NAL212_2185 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (567 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1357 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1400 aa)
AEJ00723.1KEGG: nit:NAL212_1782 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component. (946 aa)
AEJ00724.12-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (419 aa)
potASpermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (361 aa)
gatAGlutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (482 aa)
AEJ00768.1ABC transporter related protein; KEGG: nit:NAL212_2115 sulfate-transporting ATPase; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core. (240 aa)
AEJ00769.1RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (482 aa)
AEJ00770.1KEGG: nit:NAL212_2113 sigma 54 modulation protein/30S ribosomal protein S30EA; TIGRFAM: Ribosomal protein S30Ae/sigma 54 modulation protein; PFAM: Ribosomal protein S30Ae/sigma 54 modulation protein. (109 aa)
AEJ00797.1MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (288 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (253 aa)
AEJ00816.1KEGG: nit:NAL212_1400 thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiamineS. (67 aa)
cysASulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (366 aa)
AEJ00879.1KEGG: eli:ELI_09345 hypothetical protein. (450 aa)
tatCSec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (264 aa)
tatBSec-independent protein translocase protein tatB-like protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (132 aa)
tatASec-independent protein translocase protein tatA/E-like protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (113 aa)
AEJ00912.1Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: gpb:HDN1F_37290 hypothetical protein. (294 aa)
xseAExodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (448 aa)
AEJ00938.1PFAM: DNA helicase, UvrD/REP type; KEGG: nit:NAL212_1385 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1158 aa)
AEJ00948.1Two component transcriptional regulator PhoB, winged helix family; TIGRFAM: Signal transduction response regulator, phosphate regulon transcriptional regulatory protein phoB; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; KEGG: nit:NAL212_1104 two component transcriptional regulator PhoB, winged helix family; SMART: Signal transduction response regulator, receiver region. (242 aa)
AEJ00961.1Phosphate ABC transporter, periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (350 aa)
AEJ00997.1KEGG: nit:NAL212_2831 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region. (231 aa)
AEJ01029.1ABC transporter related protein; KEGG: nit:NAL212_1691 Fe(3+)-transporting ATPase; PFAM: ABC transporter-like; Transport-associated OB, type 2; SMART: ATPase, AAA+ type, core; Belongs to the ABC transporter superfamily. (351 aa)
AEJ01037.1KEGG: nit:NAL212_1301 polysaccharide export protein EpsE; TIGRFAM: Polysaccharide export EpsE; PFAM: Polysaccharide export protein; Soluble ligand binding domain. (270 aa)
AEJ01040.1KEGG: nit:NAL212_1304 exosortase 2; TIGRFAM: Exosortase 2; Exosortase, EpsH; PFAM: Exosortase EpsH-related. (297 aa)
AEJ01059.1KEGG: nit:NAL212_2625 hypothetical protein. (388 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvPAGlycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (450 aa)
gcvPBGlycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (483 aa)
AEJ01092.1PFAM: Protein of unknown function DUF86; KEGG: pna:Pnap_0134 hypothetical protein. (128 aa)
AEJ01132.1KEGG: cai:Caci_0551 hypothetical protein. (284 aa)
AEJ01185.1PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; KEGG: mca:MCA2725 NAD-reducing hydrogenase, gamma subunit. (243 aa)
AEJ01226.1KEGG: bgl:bglu_1g15310 hypothetical protein. (326 aa)
AEJ00288.1Two component transcriptional regulator, winged helix family; KEGG: bgl:bglu_2g22620 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region. (232 aa)
ruvBHolliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (348 aa)
ruvAHolliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (194 aa)
atpCATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa)
atpD-2ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (459 aa)
atpGATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa)
atpA-2ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa)
atpHATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (178 aa)
atpF-2ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (157 aa)
atpE-2ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (90 aa)
atpB-2ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (269 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (217 aa)
AEJ00228.1PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: nit:NAL212_2526 peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S24 family. (201 aa)
AEJ00199.1KEGG: nit:NAL212_2598 IstB domain-containing protein ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core. (273 aa)
AEJ00170.1Helix-turn-helix domain protein; KEGG: nit:NAL212_2452 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3. (102 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (599 aa)
AEJ00156.1Sigma-70 region 4 type 2; KEGG: wch:wcw_0673 hypothetical protein; PFAM: RNA polymerase sigma factor 70, region 4 type 2; SMART: ATPase, AAA+ type, core. (327 aa)
AEJ00137.1PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; KEGG: nit:NAL212_3150 TonB-dependent receptor. (683 aa)
AEJ00124.1TIGRFAM: Competence protein ComEA, helix-hairpin-helix region; PFAM: Helix-hairpin-helix motif; KEGG: nit:NAL212_0625 competence protein ComEA helix-hairpin-helix repeat-containing protein; SMART: Helix-hairpin-helix DNA-binding motif, class 1. (95 aa)
AEJ00117.1KEGG: nit:NAL212_0631 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6; PFAM: FAD dependent oxidoreductase. (389 aa)
AEJ00111.1PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: ipo:Ilyop_0907 restriction modification system DNA specificity domain protein. (558 aa)
AEJ00110.1KEGG: noc:Noc_1205 hypothetical protein; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SMART: DEAD-like helicase, N-terminal. (937 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1153 aa)
AEJ00092.1KEGG: neu:NE1584 hypothetical protein; TIGRFAM: Addiction module toxin, RelE/StbE; PFAM: Plasmid stabilisation system. (98 aa)
AEJ00091.1Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (82 aa)
AEJ00081.1KEGG: nit:NAL212_2895 fimbrial protein pilin. (152 aa)
AEJ00076.1KEGG: nit:NAL212_2900 general secretion pathway, GspH. (174 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (160 aa)
AEJ00028.1Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: nit:NAL212_0454 metal dependent phosphohydrolase. (303 aa)
AEJ00022.1Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (83 aa)
AEJ00020.1PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: gfo:GFO_2591 type I restriction-modification system DNA specificity subunit. (401 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
AEJ00010.1PFAM: HpcH/HpaI aldolase; KEGG: nit:NAL212_0420 citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (316 aa)
AEI99967.1PFAM: Outer membrane protein, OmpA/MotB, C-terminal; KEGG: shw:Sputw3181_2243 OmpA/MotB domain-containing protein. (286 aa)
AEI99954.1KEGG: dba:Dbac_0944 alternate F1F0 ATPase, F1 subunit gamma; TIGRFAM: Alternate ATPase, F1 complex, subunit gamma; PFAM: ATPase, F1 complex, gamma subunit. (315 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (533 aa)
atpFATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (346 aa)
atpEATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (93 aa)
atpBATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (233 aa)
AEI99947.1KEGG: rfr:Rfer_1162 F0F1 ATP synthase subunit epsilon; TIGRFAM: alternate F1F0 ATPase, F1 subunit epsilon; PFAM: ATPase, F1 complex, delta/epsilon subunit, N-terminal. (134 aa)
atpDATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (479 aa)
AEI99920.1KEGG: nit:NAL212_0169 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal. (604 aa)
AEI99910.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (371 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (212 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
AEJ02231.1KEGG: nit:NAL212_0989 hypothetical protein. (250 aa)
AEJ02135.1TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: nit:NAL212_1980 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. (599 aa)
AEJ02126.1PFAM: Uncharacterised protein family UPF0150; KEGG: neu:NE1268 hypothetical protein. (68 aa)
AEJ02125.1YcfA family protein; PFAM: YcfA-like; KEGG: cyc:PCC7424_4650 YcfA family protein. (66 aa)
AEJ02120.1PFAM: Methyltransferase type 11; KEGG: nit:NAL212_2034 arsenite methyltransferase. (348 aa)
AEJ02091.1PFAM: Plasmid stabilisation system; KEGG: nit:NAL212_0367 plasmid stabilization system. (88 aa)
AEJ02076.1PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: nit:NAL212_2526 peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S24 family. (201 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (244 aa)
AEJ02034.1Two component transcriptional regulator PhoB, winged helix family; TIGRFAM: Signal transduction response regulator, phosphate regulon transcriptional regulatory protein phoB; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; KEGG: nit:NAL212_2336 two component transcriptional regulator PhoB, winged helix family; SMART: Signal transduction response regulator, receiver region. (240 aa)
AEJ01990.1PFAM: Helix-turn-helix, Fis-type; KEGG: nit:NAL212_1728 transcriptional regulator, Fis family; Belongs to the transcriptional regulatory Fis family. (80 aa)
AEJ01988.1KEGG: nit:NAL212_1726 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6; PFAM: FAD dependent oxidoreductase. (390 aa)
hypAHydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)
uvrCUvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (605 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (728 aa)
AEJ01930.1PFAM: Rieske [2Fe-2S] iron-sulphur domain; KEGG: nit:NAL212_1941 rieske (2Fe-2S) iron-sulfur domain. (368 aa)
AEJ01919.1PFAM: ABC transporter-like; KEGG: nmu:Nmul_A0982 spermidine/putrescine ABC transporter ATP-binding subunit. (159 aa)
AEJ01909.1Ribonucleoside-diphosphate reductase, alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (954 aa)
AEJ01908.1Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (398 aa)
AEJ01905.1PFAM: Plasmid stabilisation system; KEGG: nit:NAL212_2501 plasmid stabilization system. (85 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
AEJ01891.1PFAM: Uncharacterised protein family UPF0150; KEGG: alv:Alvin_0648 hypothetical protein. (70 aa)
AEJ01890.1YcfA family protein; PFAM: YcfA-like; KEGG: nhl:Nhal_0117 YcfA family protein. (62 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (679 aa)
AEJ01839.1KEGG: rsc:RCFBP_11467 DNA primase-like protein. (360 aa)
AEJ01837.1KEGG: rsc:RCFBP_11467 DNA primase-like protein. (162 aa)
AEJ01826.1PFAM: DNA polymerase III chi subunit, HolC; KEGG: nit:NAL212_2233 DNA polymerase III chi subunit HolC. (140 aa)
AEJ01811.1KEGG: nit:NAL212_2421 FeS assembly protein SufD; TIGRFAM: SUF system FeS cluster assembly, SufD; PFAM: SUF system FeS cluster assembly, SufBD. (436 aa)
AEJ01810.1TIGRFAM: ATPase SufC, SUF system FeS cluster assembly; PFAM: ABC transporter-like; KEGG: nit:NAL212_2422 FeS assembly ATPase SufC; SMART: ATPase, AAA+ type, core. (263 aa)
AEJ01809.1KEGG: nit:NAL212_2423 FeS assembly protein SufB; TIGRFAM: SUF system FeS cluster assembly, SufB; PFAM: SUF system FeS cluster assembly, SufBD. (478 aa)
AEJ01797.1KEGG: plt:Plut_1823 hypothetical protein. (295 aa)
AEJ01795.1KEGG: dak:DaAHT2_2022 hypothetical protein. (1003 aa)
uvrBUvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (687 aa)
AEJ01771.1KEGG: bgl:bglu_1g26240 two component transcriptional regulator, winged helix family protein; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region. (227 aa)
clpXATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (425 aa)
AEJ01705.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (886 aa)
AEJ01704.1Catalytic domain-containing protein of components of various dehydrogenase complexes; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (436 aa)
AEJ01683.1PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal; NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal; KEGG: slt:Slit_2280 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (310 aa)
AEJ01668.1Two component transcriptional regulator, winged helix family; KEGG: response regulator, OmpR family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region. (227 aa)
AEJ01617.1KEGG: nit:NAL212_2625 hypothetical protein. (411 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (188 aa)
cysDTIGRFAM: Sulphate adenylyltransferase, small subunit; HAMAP: Sulfate adenylyltransferase subunit 2; KEGG: nit:NAL212_1834 sulfate adenylyltransferase, small subunit; PFAM: Phosphoadenosine phosphosulphate reductase. (298 aa)
cysCSulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (636 aa)
AEJ01562.1KEGG: nit:NAL212_0939 hypothetical protein. (451 aa)
AEJ01555.1PFAM: Dak kinase; Dak phosphatase; KEGG: nit:NAL212_1378 glycerone kinase. (576 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (534 aa)
sucD-2succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
AEJ01490.1PFAM: Phosphate-selective porin O/P; KEGG: nit:NAL212_1922 phosphate-selective porin O and P. (419 aa)
AEJ01477.1Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: nit:NAL212_1337 putative signal transduction protein. (294 aa)
AEJ01456.1PFAM: ThiamineS; KEGG: neu:NE2351 hypothetical protein. (105 aa)
AEJ01432.1KEGG: nhl:Nhal_2897 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: NADH-quinone oxidoreductase, chain M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (490 aa)
AEJ01429.1KEGG: nhl:Nhal_2894 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: NADH-quinone oxidoreductase, chain M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (530 aa)
hslUATP-dependent hsl protease ATP-binding subunit hslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa)
hslVATP-dependent protease hslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (173 aa)
AEJ01412.1PFAM: Phosphate-selective porin O/P; KEGG: nit:NAL212_2304 phosphate-selective porin O and P. (585 aa)
AEJ01392.1TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: nit:NAL212_2351 DNA polymerase III, delta prime subunit. (346 aa)
AEJ01382.1Protein of unknown function DUF140; KEGG: nit:NAL212_2362 hypothetical protein; TIGRFAM: Protein of unknown function DUF140; PFAM: Protein of unknown function DUF140. (387 aa)
parCDNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (794 aa)
AEJ01348.1PFAM: Permease YjgP/YjgQ, predicted; KEGG: nit:NAL212_2669 permease YjgP/YjgQ family protein. (359 aa)
AEJ01317.1KEGG: nit:NAL212_2626 hypothetical protein. (363 aa)
AEJ01301.1YcfA family protein; PFAM: YcfA-like; KEGG: bpe:BP0939 hypothetical protein. (95 aa)
AEJ01300.1PFAM: Uncharacterised protein family UPF0150; KEGG: axy:AXYL_04720 hypothetical protein. (129 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (117 aa)
AEJ03247.1KEGG: nit:NAL212_0228 HhH-GPD family protein; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. (231 aa)
AEJ03243.1PFAM: Rickettsia 17kDa surface antigen; KEGG: net:Neut_2403 OmpA/MotB domain-containing protein. (200 aa)
AEJ03215.1PFAM: Methyltransferase type 12; KEGG: rrj:RrIowa_0829 methyltransferase. (424 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (395 aa)
rpsBRibosomal protein S2; KEGG: nit:NAL212_3124 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (239 aa)
AEJ03135.1Hypothetical protein. (202 aa)
AEJ03130.1KEGG: geb:GM18_1754 hypothetical protein. (94 aa)
AEJ03112.1PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; KEGG: nit:NAL212_0642 ferredoxin--nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (580 aa)
AEJ03109.1KEGG: nmu:Nmul_A1148 sulfate adenylyltransferase subunit 2; TIGRFAM: Sulphate adenylyltransferase, small subunit; PFAM: Phosphoadenosine phosphosulphate reductase. (301 aa)
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (425 aa)
AEJ03099.1PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: ecl:EcolC_3719 restriction modification system DNA specificity subunit. (589 aa)
AEJ03096.1EcoEI R domain protein; KEGG: nit:NAL212_0226 type I site-specific deoxyribonuclease; PFAM: Restriction endonuclease, type I, EcoEI, R subunit/Type III, Res subunit, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal. (787 aa)
AEJ03084.1PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: mjl:Mjls_2226 restriction modification system DNA specificity subunit. (463 aa)
AEJ03083.1Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (91 aa)
AEJ03036.1Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (80 aa)
AEJ03035.1KEGG: neu:NE1352 hypothetical protein; TIGRFAM: Addiction module toxin, Txe/YoeB; PFAM: Addiction module toxin, Txe/YoeB. (86 aa)
AEJ03029.1PFAM: Phosphate-selective porin O/P; KEGG: mei:Msip34_2149 phosphate-selective porin O and P. (446 aa)
AEJ00309.1TIGRFAM: ATPase, type I secretion system, PrtD; PFAM: ABC transporter-like; ABC transporter, transmembrane region; KEGG: nit:NAL212_2102 type I secretion system ATPase; SMART: ATPase, AAA+ type, core. (596 aa)
AEJ03010.1KEGG: nit:NAL212_2969 lipoprotein releasing system, transmembrane protein, LolC/E family; TIGRFAM: Lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: Protein of unknown function DUF214, permase predicted. (415 aa)
AEJ02995.1KEGG: nit:NAL212_2915 general secretion pathway protein G; TIGRFAM: General secretion pathway protein G; Prepilin-type cleavage/methylation, N-terminal; PFAM: Type II secretion system protein G; Prepilin-type cleavage/methylation, N-terminal. (144 aa)
AEJ02979.1PFAM: Protein of unknown function DUF86; KEGG: nhl:Nhal_0890 protein of unknown function DUF86. (118 aa)
ilvAThreonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (503 aa)
mutLDNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (597 aa)
AEJ02952.1PFAM: Permease YjgP/YjgQ, predicted; KEGG: nit:NAL212_2670 permease YjgP/YjgQ family protein. (353 aa)
AEJ02951.1PFAM: Permease YjgP/YjgQ, predicted; KEGG: nit:NAL212_2669 permease YjgP/YjgQ family protein. (358 aa)
xseBExodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (83 aa)
AEJ02919.1KEGG: rme:Rmet_1540 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. (352 aa)
AEJ02913.1PFAM: Porin, Gram-negative type; KEGG: nit:NAL212_0692 porin. (403 aa)
uvrAUvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (939 aa)
AEJ02898.1KEGG: nit:NAL212_2589 regulatory protein ArsR; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR. (110 aa)
AEJ02890.1PFAM: FAD dependent oxidoreductase; KEGG: nit:NAL212_2630 glycerol-3-phosphate dehydrogenase. (529 aa)
rpmFTIGRFAM: Ribosomal protein L32p; HAMAP: Ribosomal protein L32p; KEGG: nit:NAL212_0666 50S ribosomal protein L32; PFAM: Ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family. (59 aa)
AEJ02854.1Cytochrome b/b6 domain-containing protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (411 aa)
AEJ02841.1PFAM: Metal-dependent hydrolase HDOD; KEGG: nit:NAL212_0572 metal-dependent hydrolase HDOD. (282 aa)
AEJ02838.1KEGG: nit:NAL212_0575 glutamine amidotransferase of anthranilate synthase; TIGRFAM: Glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I, C-terminal. (187 aa)
priBSingle-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (98 aa)
AEJ02833.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (461 aa)
bamDOuter membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (258 aa)
AEJ02808.1PFAM: NADPH-dependent FMN reductase; KEGG: pna:Pnap_0016 NADPH-dependent FMN reductase. (375 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (439 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (691 aa)
AEJ02726.1Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: bug:BC1001_1292 putative signal transduction protein. (475 aa)
AEJ02710.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (613 aa)
AEJ02680.1KEGG: nit:NAL212_2737 NADH-quinone oxidoreductase, E subunit; TIGRFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit. (158 aa)
AEJ02679.1NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (425 aa)
AEJ02678.1NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (803 aa)
AEJ02672.1KEGG: nit:NAL212_2729 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: NADH-quinone oxidoreductase, chain M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (494 aa)
rtcBProtein of unknown function UPF0027; PFAM: Uncharacterised protein family UPF0027; KEGG: nmu:Nmul_A0903 hypothetical protein; Belongs to the RtcB family. (475 aa)
AEJ02657.1Protein of unknown function DUF101; PFAM: Archease, tRNA m5C methyltransferase chaperone; KEGG: nmu:Nmul_A0902 hypothetical protein. (135 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (493 aa)
AEJ02625.1KEGG: nit:NAL212_1569 TonB-dependent vitamin B12 receptor; TIGRFAM: TonB-dependent vitamin B12 receptor; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel. (611 aa)
gyrADNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (856 aa)
rpsLRibosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (125 aa)
Your Current Organism:
Nitrosomonas sp. Is79A3
NCBI taxonomy Id: 261292
Other names: N. sp. Is79A3
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