STRINGSTRING
dnaA dnaA AEJ00155.1 AEJ00155.1 AEJ00156.1 AEJ00156.1 dnaG dnaG AEJ00199.1 AEJ00199.1 AEJ00408.1 AEJ00408.1 AEJ00528.1 AEJ00528.1 AEJ00582.1 AEJ00582.1 AEJ01236.1 AEJ01236.1 AEJ01328.1 AEJ01328.1 dnaQ dnaQ AEJ01634.1 AEJ01634.1 AEJ01837.1 AEJ01837.1 AEJ01839.1 AEJ01839.1 priA priA AEJ02135.1 AEJ02135.1 AEJ02189.1 AEJ02189.1 AEJ02366.1 AEJ02366.1 AEJ02382.1 AEJ02382.1 rplB rplB AEJ02833.1 AEJ02833.1 priB priB AEJ03087.1 AEJ03087.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaAChromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (457 aa)
AEJ00155.1KEGG: pth:PTH_2877 hypothetical protein. (155 aa)
AEJ00156.1Sigma-70 region 4 type 2; KEGG: wch:wcw_0673 hypothetical protein; PFAM: RNA polymerase sigma factor 70, region 4 type 2; SMART: ATPase, AAA+ type, core. (327 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (599 aa)
AEJ00199.1KEGG: nit:NAL212_2598 IstB domain-containing protein ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core. (273 aa)
AEJ00408.1KEGG: nit:NAL212_0714 DnaA regulatory inactivator Hda; TIGRFAM: Chromosomal replication control, regulator Hda; PFAM: Chromosomal replication control, initiator (DnaA)/regulator (Hda); Belongs to the DnaA family. (225 aa)
AEJ00528.1Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
AEJ00582.1KEGG: nit:NAL212_1757 MgsA AAA+ ATPase domain-containing protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core. (444 aa)
AEJ01236.1KEGG: rpf:Rpic12D_3448 hypothetical protein. (273 aa)
AEJ01328.1KEGG: nit:NAL212_2045 hypothetical protein. (870 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (247 aa)
AEJ01634.1KEGG: dak:DaAHT2_2156 hypothetical protein. (538 aa)
AEJ01837.1KEGG: rsc:RCFBP_11467 DNA primase-like protein. (162 aa)
AEJ01839.1KEGG: rsc:RCFBP_11467 DNA primase-like protein. (360 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (728 aa)
AEJ02135.1TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: nit:NAL212_1980 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. (599 aa)
AEJ02189.1PFAM: Virulence-associated E; KEGG: net:Neut_1478 virulence-associated E family protein. (789 aa)
AEJ02366.1PFAM: Protein of unknown function DUF927; KEGG: pfl:PFL_4979 hypothetical protein. (951 aa)
AEJ02382.1KEGG: nit:NAL212_1452 DNA repair protein RadC; TIGRFAM: DNA repair, RadC-like; PFAM: DNA repair, RadC-like; Belongs to the UPF0758 family. (224 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (277 aa)
AEJ02833.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (461 aa)
priBSingle-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (98 aa)
AEJ03087.1Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (110 aa)
Your Current Organism:
Nitrosomonas sp. Is79A3
NCBI taxonomy Id: 261292
Other names: N. sp. Is79A3
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