(27 nodes) Ribonuclease H-like superfamily network (Nitrosomonas sp. Is79A3)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	AEJ00935.1	PFAM: Transposase, IS4-like; KEGG: amt:Amet_1582 hypothetical protein. (443 aa)
	AEJ00088.1	PFAM: Transposase, IS4-like; KEGG: cph:Cpha266_2339 transposase, IS4 family protein. (388 aa)
	AEJ00167.1	PFAM: Integrase, catalytic core; KEGG: rso:RSp0548 ISRSO8-transposase orfB protein. (291 aa)
	AEJ00172.1	PFAM: Integrase, catalytic core; KEGG: rso:RSp0548 ISRSO8-transposase orfB protein. (292 aa)
	AEJ00185.1	KEGG: afe:Lferr_1426 integrase catalytic subunit; manually curated; PFAM: Integrase, catalytic core. (302 aa)
	AEJ00225.1	PFAM: Transposase, IS4-like; KEGG: dar:Daro_2223 transposase IS4. (388 aa)
	AEJ00229.1	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal. (463 aa)
	AEJ00231.1	Ribonuclease H; KEGG: pat:Patl_3400 ribonuclease H. (166 aa)
	orn	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (196 aa)
	ruvC	Crossover junction endodeoxyribonuclease ruvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (177 aa)
	AEJ00286.1	PFAM: Transposase, IS4-like; KEGG: dar:Daro_2223 transposase IS4. (388 aa)
	AEJ00448.1	Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (161 aa)
	AEJ00577.1	KEGG: nit:NAL212_1762 Tex-like protein; PFAM: Tex-like protein, N-terminal; Ribosomal protein S1, RNA binding domain; SMART: Resolvase, RNase H-like fold. (742 aa)
	AEJ00915.1	PFAM: Integrase, catalytic core; KEGG: rso:RSp0548 ISRSO8-transposase orfB protein. (291 aa)
	AEJ00045.1	PFAM: Integrase, catalytic core; KEGG: ppu:PP_4459 transposase, putative. (354 aa)
	AEJ01048.1	KEGG: cph:Cpha266_2339 transposase, IS4 family protein; manually curated; PFAM: Transposase, IS4-like. (378 aa)
	polA	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (915 aa)
	rnhA	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (154 aa)
	dnaQ	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (247 aa)
	AEJ01731.1	PFAM: Transposase, IS4-like; KEGG: dar:Daro_2223 transposase IS4. (388 aa)
	AEJ02075.1	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal. (463 aa)
	AEJ02078.1	PFAM: Transposase, IS4-like; KEGG: dar:Daro_2223 transposase IS4. (388 aa)
	AEJ02272.1	PFAM: Integrase, catalytic core; KEGG: rso:RSp0548 ISRSO8-transposase orfB protein. (308 aa)
	AEJ02474.1	PFAM: Integrase, catalytic core; KEGG: rso:RSp0548 ISRSO8-transposase orfB protein. (292 aa)
	AEJ02768.1	KEGG: afe:Lferr_1426 integrase catalytic subunit; manually curated; PFAM: Integrase, catalytic core. (310 aa)
	AEJ02983.1	Exonuclease domain protein; PFAM: Exonuclease C-terminal; Exonuclease, RNase T/DNA polymerase III; KEGG: nit:NAL212_2927 exodeoxyribonuclease I. (477 aa)
	rnhB	Ribonuclease HII/HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (202 aa)

Your Current Organism:

Nitrosomonas sp. Is79A3

NCBI taxonomy Id: 261292
Other names: N. sp. Is79A3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEJ00229.1	AEJ02075.1	Nit79A3_0341	Nit79A3_2299	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	0.946
AEJ00229.1	dnaQ	Nit79A3_0341	Nit79A3_1632	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.950
AEJ00229.1	polA	Nit79A3_0341	Nit79A3_1314	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.748
AEJ00229.1	ruvC	Nit79A3_0341	Nit79A3_0378	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	Crossover junction endodeoxyribonuclease ruvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.	0.428
AEJ00231.1	polA	Nit79A3_0343	Nit79A3_1314	Ribonuclease H; KEGG: pat:Patl_3400 ribonuclease H.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.546
AEJ00231.1	rnhB	Nit79A3_0343	Nit79A3_3480	Ribonuclease H; KEGG: pat:Patl_3400 ribonuclease H.	Ribonuclease HII/HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.709
AEJ02075.1	AEJ00229.1	Nit79A3_2299	Nit79A3_0341	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	0.946
AEJ02075.1	dnaQ	Nit79A3_2299	Nit79A3_1632	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.950
AEJ02075.1	polA	Nit79A3_2299	Nit79A3_1314	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.748
AEJ02075.1	ruvC	Nit79A3_2299	Nit79A3_0378	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	Crossover junction endodeoxyribonuclease ruvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.	0.428
AEJ02983.1	polA	Nit79A3_3249	Nit79A3_1314	Exonuclease domain protein; PFAM: Exonuclease C-terminal; Exonuclease, RNase T/DNA polymerase III; KEGG: nit:NAL212_2927 exodeoxyribonuclease I.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.414
dnaQ	AEJ00229.1	Nit79A3_1632	Nit79A3_0341	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	0.950
dnaQ	AEJ02075.1	Nit79A3_1632	Nit79A3_2299	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	0.950
dnaQ	orn	Nit79A3_1632	Nit79A3_0352	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	0.444
dnaQ	polA	Nit79A3_1632	Nit79A3_1314	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.650
dnaQ	rnhA	Nit79A3_1632	Nit79A3_1631	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.984
orn	dnaQ	Nit79A3_0352	Nit79A3_1632	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.444
orn	polA	Nit79A3_0352	Nit79A3_1314	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.437
polA	AEJ00229.1	Nit79A3_1314	Nit79A3_0341	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal; KEGG: nit:NAL212_2527 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal.	0.748
polA	AEJ00231.1	Nit79A3_1314	Nit79A3_0343	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Ribonuclease H; KEGG: pat:Patl_3400 ribonuclease H.	0.546