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GBAA_0875 GBAA_0875 GBAA_0993 GBAA_0993 hemE hemE hemH1 hemH1 hemY1 hemY1 hemH2 hemH2 GBAA_1875 GBAA_1875 hemY2 hemY2 yetG yetG hemN hemN isdG isdG GBAA_5637 GBAA_5637
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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Your Input:
GBAA_0875Putative oxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055. (496 aa)
GBAA_0993Conserved hypothetical protein; Identified by match to protein family HMM PF00210; match to protein family HMM PF02915. (146 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (348 aa)
hemH1Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (311 aa)
hemY1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (456 aa)
hemH2Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (319 aa)
GBAA_1875Putative coenzyme PQQ synthesis protein; Identified by match to protein family HMM PF04055. (377 aa)
hemY2Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (466 aa)
yetGConserved hypothetical protein; Identified by match to protein family HMM PF03992. (108 aa)
hemNOxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (378 aa)
isdGConserved hypothetical protein; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. (107 aa)
GBAA_5637Conserved hypothetical protein; May function as heme-dependent peroxidase. (247 aa)
Your Current Organism:
Bacillus anthracis
NCBI taxonomy Id: 261594
Other names: B. anthracis str. 'Ames Ancestor', Bacillus anthracis str. 'Ames Ancestor', Bacillus anthracis str. Ames 0581, Bacillus anthracis str. Ames Ancestor
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