21 items (Bacillus anthracis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	hemL1	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. (434 aa)
	GBAA_0875	Putative oxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055. (496 aa)
	hemE	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (348 aa)
	hemH1	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (311 aa)
	hemY1	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (456 aa)
	hemH2	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (319 aa)
	cysG	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (258 aa)
	GBAA_1446	cbiX domain protein; Identified by match to protein family HMM PF01903. (251 aa)
	GBAA_1447	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470. (205 aa)
	GBAA_2142	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470. (157 aa)
	GBAA_2143	cbiX domain protein; Identified by match to protein family HMM PF01903. (236 aa)
	cobA	Putative uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469. (474 aa)
	hemY2	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (466 aa)
	ctaB	Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (307 aa)
	ctaA	Cytochrome aa3 controlling protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily. (311 aa)
	hemL2	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. (429 aa)
	hemB	Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (329 aa)
	hemD	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (250 aa)
	hemC	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa)
	hemA	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (444 aa)
	GBAA_5637	Conserved hypothetical protein; May function as heme-dependent peroxidase. (247 aa)

Your Current Organism:

Bacillus anthracis

NCBI taxonomy Id: 261594
Other names: B. anthracis str. 'Ames Ancestor', Bacillus anthracis str. 'Ames Ancestor', Bacillus anthracis str. Ames 0581, Bacillus anthracis str. Ames Ancestor

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GBAA_0875	cobA	GBAA_0875	GBAA_2144	Putative oxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055.	Putative uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469.	0.498
GBAA_0875	hemE	GBAA_0875	GBAA_1070	Putative oxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.926
GBAA_0875	hemY1	GBAA_0875	GBAA_1072	Putative oxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.918
GBAA_0875	hemY2	GBAA_0875	GBAA_2418	Putative oxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.918
GBAA_1446	GBAA_1447	GBAA_1446	GBAA_1447	cbiX domain protein; Identified by match to protein family HMM PF01903.	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	0.993
GBAA_1446	GBAA_2142	GBAA_1446	GBAA_2142	cbiX domain protein; Identified by match to protein family HMM PF01903.	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	0.971
GBAA_1446	cobA	GBAA_1446	GBAA_2144	cbiX domain protein; Identified by match to protein family HMM PF01903.	Putative uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469.	0.777
GBAA_1446	cysG	GBAA_1446	GBAA_1445	cbiX domain protein; Identified by match to protein family HMM PF01903.	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	0.976
GBAA_1447	GBAA_1446	GBAA_1447	GBAA_1446	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	cbiX domain protein; Identified by match to protein family HMM PF01903.	0.993
GBAA_1447	GBAA_2142	GBAA_1447	GBAA_2142	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	0.921
GBAA_1447	GBAA_2143	GBAA_1447	GBAA_2143	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	cbiX domain protein; Identified by match to protein family HMM PF01903.	0.706
GBAA_1447	cobA	GBAA_1447	GBAA_2144	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	Putative uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469.	0.995
GBAA_1447	cysG	GBAA_1447	GBAA_1445	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	0.999
GBAA_1447	hemA	GBAA_1447	GBAA_4698	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.561
GBAA_1447	hemB	GBAA_1447	GBAA_4694	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.	0.719
GBAA_1447	hemC	GBAA_1447	GBAA_4696	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.878
GBAA_1447	hemD	GBAA_1447	GBAA_4695	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.562
GBAA_1447	hemL1	GBAA_1447	GBAA_0531	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713.	0.461
GBAA_1447	hemL2	GBAA_1447	GBAA_4693	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713.	0.499
GBAA_2142	GBAA_1446	GBAA_2142	GBAA_1446	Siroheme synthase, precorrin 2 oxidase and ferrochelatase domains; Identified by match to protein family HMM TIGR01470.	cbiX domain protein; Identified by match to protein family HMM PF01903.	0.971

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