STRINGSTRING
spoIIP spoIIP spoIVFB spoIVFB etfA etfA tpx tpx sspB sspB smpB smpB spoIIID spoIIID spoIID spoIID spoIIR spoIIR spo0F spo0F gerQ gerQ cotE cotE spoVK spoVK sspO sspO sspN sspN tlp tlp sleL sleL arsC arsC gerAA gerAA cotF cotF sleB sleB ypeB ypeB spoVB spoVB cotH cotH spoIVA spoIVA spmA spmA cotJA cotJA cotJB cotJB cotJC cotJC spoVR spoVR gerKA gerKA gerKB gerKB gerKC gerKC cwlD cwlD yabQ yabQ yabP yabP spoVG spoVG sspF sspF abrB abrB bofA bofA spoVFB spoVFB spoVFA spoVFA spoIIGA spoIIGA spoVE spoVE ylbJ ylbJ tgl tgl spoIIAB spoIIAB spoIIAA spoIIAA spoIIM spoIIM spoIIIAD spoIIIAD spoIIIAC spoIIIAC spoIIIAB spoIIIAB spoIIIAA spoIIIAA yqfD yqfD yqfC yqfC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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spoIIPStage II sporulation protein P; Identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867. (384 aa)
spoIVFBStage IV sporulation protein FB; Identified by match to protein family HMM PF02163. (286 aa)
etfAElectron transfer flavoprotein, alpha subunit; Identified by match to protein family HMM PF00766; match to protein family HMM PF01012. (325 aa)
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (166 aa)
sspBSmall, acid-soluble spore protein B; Identified by match to protein family HMM PF00269. (65 aa)
smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (155 aa)
spoIIIDStage III sporulation protein D; Identified by match to protein family HMM TIGR02844. (132 aa)
spoIIDStage II sporulation protein D; Identified by match to protein family HMM PF08486; match to protein family HMM TIGR02669; match to protein family HMM TIGR02870. (339 aa)
spoIIRPutative stage II sporulation protein R; Identified by match to protein family HMM TIGR02837. (288 aa)
spo0FSporulation initiation phosphotransferase F; Identified by match to protein family HMM PF00072. (122 aa)
gerQSpore coat protein GerQ; Identified by match to protein family HMM TIGR02728. (145 aa)
cotESpore coat protein E. (180 aa)
spoVKStage V sporulation protein K; Identified by match to protein family HMM PF00004; match to protein family HMM TIGR02881. (318 aa)
sspOSmall, acid-soluble spore protein O; Identified by match to protein family HMM TIGR02864; Belongs to the SspO family. (49 aa)
sspNConserved hypothetical protein; Identified by match to protein family HMM PF08177; Belongs to the SspN family. (44 aa)
tlpIdentified by match to protein family HMM TIGR03090; Belongs to the Tlp family. (65 aa)
sleLGlycosyl hydrolase, family 18; N-acetylglucosaminidase involved in cortex peptidoglycan degradation during germination. Cleaves only partially degraded spore peptidoglycans. Recognizes muramic acid delta-lactam residues specific to spore peptidoglycans. (430 aa)
arsCArsenate reductase (thioredoxin); Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. (134 aa)
gerAASpore germination protein GerAA; Identified by match to protein family HMM PF03323. (437 aa)
cotFIdentified by match to protein family HMM PF07875. (159 aa)
sleBSpore cortex-lytic enzyme prepeptide; Identified by match to protein family HMM PF01471; match to protein family HMM PF07486; match to protein family HMM TIGR02869. (253 aa)
ypeBGermination protein YpeB; Identified by match to protein family HMM PF03413; match to protein family HMM TIGR02889. (446 aa)
spoVBStage V sporulation protein B; Identified by match to protein family HMM PF01943; match to protein family HMM TIGR02900. (519 aa)
cotHIdentified by match to protein family HMM PF08757. (358 aa)
spoIVAStage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Directs the assembly of the coat and exosporium to an area around the forespore. (492 aa)
spmAIdentified by match to protein family HMM PF07670. (198 aa)
cotJAcotJA protein. (71 aa)
cotJBcotJB protein. (91 aa)
cotJCcotJC protein; Identified by match to protein family HMM PF05067. (189 aa)
spoVRStage V sporulation protein R; Identified by match to protein family HMM PF04293. (472 aa)
gerKASpore germination protein GerKA; Identified by match to protein family HMM PF03323. (500 aa)
gerKBSpore germination protein GerKB; Identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912. (368 aa)
gerKCSpore germination protein GerKC; Identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887. (374 aa)
cwlDGermination-specific N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01520; match to protein family HMM TIGR02883. (237 aa)
yabQSpore cortex biosynthesis protein YabQ; Identified by match to protein family HMM TIGR02893. (217 aa)
yabPSporulation protein YabP; Identified by match to protein family HMM PF07873; match to protein family HMM TIGR02892. (102 aa)
spoVGStage V sporulation protein G; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. (97 aa)
sspFSmall, acid-soluble spore protein; Identified by match to protein family HMM PF00269. (59 aa)
abrBTransition state transcriptional regulatory protein AbrB; Identified by similarity to SP:P08874; match to protein family HMM PF04014; match to protein family HMM TIGR01439. (94 aa)
bofASigma-k factor processing regulatory protein BofA; Identified by match to protein family HMM PF07441; match to protein family HMM TIGR02862. (89 aa)
spoVFBDipicolinate synthase, B subunit; Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA). (199 aa)
spoVFADipicolinate synthase, A subunit; Identified by match to protein family HMM PF01262; match to protein family HMM PF01488; match to protein family HMM TIGR02853. (300 aa)
spoIIGASporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. (308 aa)
spoVEStage V sporulation protein E; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; match to protein family HMM TIGR02615; Belongs to the SEDS family. (363 aa)
ylbJPutative membrane protein; Identified by match to protein family HMM PF07670; match to protein family HMM TIGR02871. (409 aa)
tglProtein-glutamine gamma-glutamyltransferase; Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. Belongs to the bacillus TGase family. (276 aa)
spoIIABAnti-sigma F factor antagonist; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (146 aa)
spoIIAAAnti-sigma F factor antagonist; Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; match to protein family HMM TIGR02886. (116 aa)
spoIIMStage II sporulation protein M; Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane. (215 aa)
spoIIIADStage III sporulation protein AD; Identified by match to protein family HMM TIGR02849. (98 aa)
spoIIIACStage III sporulation protein AC; Identified by match to protein family HMM PF06686; match to protein family HMM TIGR02848. (67 aa)
spoIIIABStage III sporulation protein AB; Identified by match to protein family HMM TIGR02833. (171 aa)
spoIIIAAStage III sporulation protein AA; Identified by match to protein family HMM TIGR02858. (308 aa)
yqfDIdentified by match to protein family HMM PF06898; match to protein family HMM TIGR02876. (399 aa)
yqfCSporulation protein YqfC; Identified by match to protein family HMM PF07241; match to protein family HMM TIGR02856. (97 aa)
Your Current Organism:
Bacillus anthracis
NCBI taxonomy Id: 261594
Other names: B. anthracis str. 'Ames Ancestor', Bacillus anthracis str. 'Ames Ancestor', Bacillus anthracis str. Ames 0581, Bacillus anthracis str. Ames Ancestor
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