STRINGSTRING
spoVT spoVT sigB sigB spoIVA spoIVA cotH cotH cotE cotE sigG sigG sigF sigF spo0A spo0A sigK sigK safA safA spoVID spoVID gerE gerE spoIIID spoIIID
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
spoVTStage V sporulation protein T; Identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; match to protein family HMM TIGR02851. (178 aa)
sigBRNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (257 aa)
spoIVAStage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Directs the assembly of the coat and exosporium to an area around the forespore. (492 aa)
cotHIdentified by match to protein family HMM PF08757. (358 aa)
cotESpore coat protein E. (180 aa)
sigGRNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (259 aa)
sigFRNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (252 aa)
spo0AStage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity). (264 aa)
sigKRNA polymerase sigma-27 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes, a sporulation-regulated event (By similarity). (237 aa)
safASpore coat assembly protein SafA; Identified by match to protein family HMM PF01476. (582 aa)
spoVIDPutative stage VI sporulation protein D; Identified by match to protein family HMM PF01476; match to protein family HMM TIGR02907. (327 aa)
gerEGermination protein GerE; Identified by match to protein family HMM PF00196; match to protein family HMM PF08281. (74 aa)
spoIIIDStage III sporulation protein D; Identified by match to protein family HMM TIGR02844. (132 aa)
Your Current Organism:
Bacillus anthracis
NCBI taxonomy Id: 261594
Other names: B. anthracis str. 'Ames Ancestor', Bacillus anthracis str. 'Ames Ancestor', Bacillus anthracis str. Ames 0581, Bacillus anthracis str. Ames Ancestor
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