STRINGSTRING
cysC cysC AEB42094.1 AEB42094.1 valS valS guaA guaA cysS cysS AEB42418.1 AEB42418.1 metG metG AEB45479.1 AEB45479.1 AEB45270.1 AEB45270.1 argS argS AEB44719.1 AEB44719.1 AEB44266.1 AEB44266.1 tyrS tyrS AEB44170.1 AEB44170.1 AEB44169.1 AEB44169.1 AEB43982.1 AEB43982.1 AEB43955.1 AEB43955.1 mshC mshC argG argG AEB45826.1 AEB45826.1 AEB46241.1 AEB46241.1 leuS leuS nadE nadE gltX gltX nadD nadD coaD coaD AEB43417.1 AEB43417.1 AEB43514.1 AEB43514.1 AEB43738.1 AEB43738.1 AEB43740.1 AEB43740.1 cysH cysH tilS tilS argS-2 argS-2 valS-2 valS-2 ileS ileS AEB46778.1 AEB46778.1 AEB42824.1 AEB42824.1 trpS trpS AEB42982.1 AEB42982.1 coaD-2 coaD-2 AEB43323.1 AEB43323.1 panC panC AEB43324.1 AEB43324.1 mnmA mnmA AEB47812.1 AEB47812.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (509 aa)
AEB42094.1COG2949 Uncharacterized membrane protein. (250 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (854 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (521 aa)
cysSCOG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (471 aa)
AEB42418.1rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (628 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (600 aa)
AEB45479.1COG2205 Osmosensitive K+ channel histidine kinase. (850 aa)
AEB45270.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (296 aa)
argSCOG0018 Arginyl-tRNA synthetase. (573 aa)
AEB44719.1Hypothetical protein; COG0367 Asparagine synthase (glutamine-hydrolyzing). (617 aa)
AEB44266.1Hypothetical protein. (224 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (435 aa)
AEB44170.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (297 aa)
AEB44169.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (279 aa)
AEB43982.1Cytidyltransferase-like protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (471 aa)
AEB43955.1COG0137 Argininosuccinate synthase. (393 aa)
mshCcysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (395 aa)
argGCOG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (483 aa)
AEB45826.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (536 aa)
AEB46241.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (653 aa)
leuSCOG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (952 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (588 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (471 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (188 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa)
AEB43417.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (162 aa)
AEB43514.1Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. (309 aa)
AEB43738.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (291 aa)
AEB43740.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (274 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (253 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (329 aa)
argS-2COG0018 Arginyl-tRNA synthetase. (554 aa)
valS-2valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (872 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1057 aa)
AEB46778.1COG3046 Uncharacterized protein related to deoxyribodipyrimidine photolyase. (490 aa)
AEB42824.1Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. (303 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (341 aa)
AEB42982.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (594 aa)
coaD-2Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (152 aa)
AEB43323.1COG2086 Electron transfer flavoprotein, beta subunit. (259 aa)
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (278 aa)
AEB43324.1COG2025 Electron transfer flavoprotein, alpha subunit. (319 aa)
mnmAtRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (351 aa)
AEB47812.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (568 aa)
Your Current Organism:
Verrucosispora maris
NCBI taxonomy Id: 263358
Other names: V. maris AB-18-032, Verrucosispora maris AB-18-032, Verrucosispora maris str. AB-18-032, Verrucosispora maris strain AB-18-032, Verrucosispora sp. AB-18-032
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