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| | PTO1519 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (776 aa) |
| | ftsY | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (315 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (414 aa) |
| | PTO1499 | Multi drug ABC transporter ATP binding protein. (290 aa) |
| | PTO1493 | Sugar ABC transporter ATP binding protein. (336 aa) |
| | PTO1482 | E1-E2 ATPase. (781 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (361 aa) |
| | lysZ | Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (252 aa) |
| | PTO1469 | RimK-like protein; Part of lysine biosynthesis. (276 aa) |
| | nadK | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (270 aa) |
| | PTO1467 | RimK-like protein; Part of lysine biosynthesis. (274 aa) |
| | PTO1451 | Oligopeptide ABC transporter Opp2, ATP binding protein. (261 aa) |
| | PTO1450 | Oligopeptide ABC transporter Opp2, ATP binding protein. (324 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa) |
| | gck | Glycerate kinase, putative; Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also partially utilize GTP, CTP or UTP as phosphate donor. (415 aa) |
| | PTO1415 | DNA gyrase subunit A. (789 aa) |
| | PTO1414 | DNA gyrase subunit B. (646 aa) |
| | PTO1412 | asparaginyl-tRNA synthetase. (427 aa) |
| | gatE | glutamyl-tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (591 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (399 aa) |
| | PTO1394 | Alpha glucoside ABC transporter ATP-binding protein. (377 aa) |
| | hel308 | Helicase involved in UV-protection; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (674 aa) |
| | tiaS | Hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (430 aa) |
| | PTO1376 | Kinase. (85 aa) |
| | PTO1375 | Kinase. (61 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (466 aa) |
| | PTO1356 | Diphosphomevalonate decarboxylase; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation. (324 aa) |
| | purC | Phosphoribosylamidoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (294 aa) |
| | PTO1352 | Mevalonate kinase. (329 aa) |
| | PTO1345 | ATP-dependent RNA helicase. (387 aa) |
| | guaAA | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (203 aa) |
| | PTO1339 | Hypothetical protein. (69 aa) |
| | PTO1337 | ATP phosphoribosyltransferase. (219 aa) |
| | PTO1322 | DNA repair helicase; Rad25/XPB family. (443 aa) |
| | PTO1320 | iron(III) dicitrate tABC ransporter, ATP-binding protein. (243 aa) |
| | PTO1318 | iron(III) dicitrate ABC transporter extracellular binding protein. (316 aa) |
| | queC | Hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (239 aa) |
| | PTO1293 | Molybdopterin-guanine dinucleotide biosynthesis protein A. (180 aa) |
| | PTO1289 | AIR Synthase. (334 aa) |
| | infB | Protein translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (580 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (140 aa) |
| | cdc6 | Origin recognition complex subunit; Involved in regulation of DNA replication. (408 aa) |
| | PTO1256 | Folylpolyglutamate synthase/dihydrofolate synthase. (435 aa) |
| | PTO1245 | ATP-dependent DNA helicase. (852 aa) |
| | fhs | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (535 aa) |
| | PTO1241 | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (773 aa) |
| | PTO1235 | ATP-dependent protease La; Belongs to the peptidase S16 family. (649 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (444 aa) |
| | PTO1230 | MoxR-like ATPase. (388 aa) |
| | PTO1217 | Cell division control protein (mcm family); Belongs to the MCM family. (694 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (423 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (741 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thoug [...] (75 aa) |
| | PTO1198 | Arsenite-transporting ATPase. (386 aa) |
| | PTO1195 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. (541 aa) |
| | PTO1194 | ATP-dependent RNA helicase. (901 aa) |
| | PTO1191 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (891 aa) |
| | PTO1179 | Rhodanese-related sulfurtransferases. (105 aa) |
| | PTO1114 | glycyl-tRNA synthetase. (474 aa) |
| | PTO1111 | ABC transporter ATP-binding protein. (258 aa) |
| | PTO1106 | Hypothetical regulatory protein. (284 aa) |
| | tmk | Putative thymidylate kinase. (202 aa) |
| | PTO1096 | Daunorubicin resistance ATP-binding protein DrrA. (327 aa) |
| | PTO1094 | N-acetylglucosamine kinase. (320 aa) |
| | PTO1060 | Molybdenum cofactor biosynthesis protein B. (158 aa) |
| | moaA | Putative molybdopterin cofactor synthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (310 aa) |
| | PTO1033 | Sugar ABC transporter 1, ATP binding protein. (333 aa) |
| | PTO1032 | Hypothetical protein. (156 aa) |
| | PTO1031 | Sugar ABC transporter 1, permease protein. (537 aa) |
| | PTO1030 | Sugar ABC transporter 1, ATP binding protein. (268 aa) |
| | ribL | Glycerol-3-phosphate cytidylyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (139 aa) |
| | PTO1003 | succinyl-CoA synthetase beta chain. (368 aa) |
| | nadE | NAD synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (249 aa) |
| | PTO0977 | Multidrug resistance ABC transporter ATP-binding and permease protein. (525 aa) |
| | PTO0976 | Multidrug resistance ABC transporter ATP-binding and permease protein. (557 aa) |
| | PTO0951 | Thiosulfate sulfurtransferase. (153 aa) |
| | PTO0950 | Phosphoribosylamine--glycine ligase. (418 aa) |
| | PTO0949 | Protein translation elongation factor. (295 aa) |
| | PTO0944 | Sua5 superfamily-related protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (337 aa) |
| | PTO0931 | Hypothetical archaeal protein. (362 aa) |
| | PTO0917 | ABC transporter ATP-binding protein. (251 aa) |
| | PTO0906 | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (288 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (347 aa) |
| | PTO0899 | Carbamoyl-phosphate synthase. (1051 aa) |
| | srp54 | Signal recognition particle protein Srp54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (456 aa) |
| | PTO0892 | asparaginyl-tRNA synthetase. (317 aa) |
| | PTO0884 | DNA repair helicase; Rad3/Rad15/XPD family. (605 aa) |
| | PTO0880 | ATP-dependent helicase. (1667 aa) |
| | PTO0879 | GTP-binding protein. (324 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (548 aa) |
| | PTO0874 | methionyl-tRNA synthetase. (108 aa) |
| | rfcL | Replication factor C, large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (410 aa) |
| | smc | Chromosome partition protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1150 aa) |
| | PTO0852 | GTP-binding protein. (371 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (357 aa) |
| | dnaK | Chaperone protein Dank; Acts as a chaperone. (613 aa) |
| | grpE | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] (180 aa) |
| | PTO0819 | Rhodanese-related sulfurtransferases. (116 aa) |
| | PTO0809 | UMP/CMP kinase related protein. (203 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (248 aa) |
| | PTO0782 | phenylalanyl-tRNA synthetase beta chain. (520 aa) |
| | PTO0765 | Oligopeptide ABC transporter Dpp1, ATP binding protein. (303 aa) |
| | PTO0764 | Oligopeptide ABC transporter Dpp1, ATP binding protein. (238 aa) |
| | mat | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (418 aa) |
| | radA | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (323 aa) |
| | PTO0740 | Ubiquione biosynthesis protein. (505 aa) |
| | PTO0735 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. (546 aa) |
| | PTO0729 | Daunorubicin resistance ATP-binding protein DrrA. (278 aa) |
| | PTO0707 | Hypothetical protein. (308 aa) |
| | PTO0683 | Oligopeptide ABC transporter Opp1, ATP binding protein. (720 aa) |
| | PTO0679 | Molybdopterin-guanine dinucleotide biosynthesis protein B. (152 aa) |
| | PTO0677 | Cobalamin periplasmic binding protein. (272 aa) |
| | lig | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (590 aa) |
| | cmk | Cytidylate kinase. (174 aa) |
| | adkA | Adenylate kinase; Belongs to the archaeal adenylate kinase family. (181 aa) |
| | PTO0631 | Long chain fatty acid CoA ligase. (557 aa) |
| | PTO0629 | Hemin-binding periplasmic protein HmuT precursor. (315 aa) |
| | PTO0618 | Putative protease La homolog type 2. (492 aa) |
| | nnrD | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (450 aa) |
| | rtcB | RtcB protein; Belongs to the RtcB family. (470 aa) |
| | PTO0603 | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (542 aa) |
| | aroK | Shikimate kinase. (279 aa) |
| | thrS | threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (710 aa) |
| | PTO0592 | Translation initiation factor eIF-2, subunit gamma. (405 aa) |
| | PTO0590 | Carbamate kinase; Belongs to the carbamate kinase family. (283 aa) |
| | rfcS | Replication factor C, small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (318 aa) |
| | PTO0579 | Maltose ABC transporter ATP-binding protein. (366 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (192 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa) |
| | PTO0555 | RNase L inhibitor homolog, predicted ATPase. (588 aa) |
| | PTO0544 | Hypothetical protein. (177 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (690 aa) |
| | PTO0536 | acyl-CoA synthetase. (657 aa) |
| | cca | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (427 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (768 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (395 aa) |
| | PTO0519 | Hypothetical protein. (158 aa) |
| | guaAB | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (305 aa) |
| | hisS | histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (423 aa) |
| | PTO0508 | Glycerol-3-phosphate cytidylyltransferase. (319 aa) |
| | PTO0497 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (242 aa) |
| | atpE | A1AO H+ ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (182 aa) |
| | atpC | A1AO H+ ATPase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (348 aa) |
| | PTO0491 | A1AO H+ ATPase subunit F. (99 aa) |
| | atpA | A1AO H+ ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (922 aa) |
| | atpB | A1AO H+ ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (460 aa) |
| | atpD | A1AO H+ ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (215 aa) |
| | PTO0178 | Magnesium-chelatase subunit ChlI. (261 aa) |
| | PTO0177 | Magnesium-chelatase subunit ChlI. (328 aa) |
| | PTO0164 | Copper transporting ATPase. (671 aa) |
| | kdpB | Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (659 aa) |
| | kdpC | Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (211 aa) |
| | PTO0135 | Serine/threonine protein kinase. (1205 aa) |
| | PTO0129 | Nicotinamide-nucleotide adenylyltransferase. (169 aa) |
| | PTO0125 | phenylalanyl-tRNA synthetase alpha chain. (479 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (440 aa) |
| | PTO0095 | ABC-type multidrug transport system, ATPase component. (315 aa) |
| | PTO0087 | glycerol-3-P ABC transporter ATP binding protein. (357 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (455 aa) |
| | PTO0076 | Type I restriction-modification system restriction subunit. (996 aa) |
| | PTO0070 | Hypothetical membrane spanning protein. (436 aa) |
| | PTO0060 | Conserved hypothetical protein. (359 aa) |
| | PTO0053 | HD domain family protein. (768 aa) |
| | PTO0028 | 5-methylcytosine-specific restriction enzyme B. (523 aa) |
| | PTO0011 | N-acetylglucosamine kinase. (329 aa) |
| | thiI | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (469 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (300 aa) |
| | PTO0472 | ABC-type multidrug transport system, ATPase component. (308 aa) |
| | PTO0468 | Phosphoribosylformylglycinamidine cyclo-ligase. (335 aa) |
| | PTO0467 | Hypothetical ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (274 aa) |
| | lysS | lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (504 aa) |
| | PTO0456 | Cell division cycle protein 48. (744 aa) |
| | mptE | Hypothetical protein DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (224 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (870 aa) |
| | fusA | Protein translation elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/ [...] (732 aa) |
| | tuf | Protein translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (424 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1024 aa) |
| | PTO0374 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] (529 aa) |
| | PTO0370 | alanyl-tRNA synthetase. (249 aa) |
| | PTO0336 | Pyruvate kinase; Belongs to the pyruvate kinase family. (555 aa) |
| | PTO0320 | Hypothetical protein. (598 aa) |
| | PTO0283 | Acetyl-coenzyme A synthetase. (650 aa) |
| | PTO0271 | LAO/AO transport system kinase ArgK. (290 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (426 aa) |
| | PTO0252 | Serine/threonine protein kinase. (255 aa) |
| | rad50 | DNA repair protein Rad50; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (880 aa) |
| | PTO0236 | GTP binding protein; GTP1/OBG family. (359 aa) |
| | PTO0232 | Pantothenate kinase. (275 aa) |
| | PTO0229 | DNA repair and recombination protein RadB. (228 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (329 aa) |
| | PTO0219 | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (180 aa) |
| | PTO0215 | Dipeptide ABC transporter Dpp1, ATP binding protein. (322 aa) |
| | PTO0214 | Dipeptide ABC transporter Dpp1, ATP binding protein. (315 aa) |
| | PTO0201 | ABC transporter ATP-binding protein. (271 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (419 aa) |
