Your Input: | |
| | ychF | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (371 aa) |
| | stu0007 | Conserved hypothetical protein, S4 domain protein. (91 aa) |
| | tilS | Putative cell-cycle protein, MesJ/Ycf62 family; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (421 aa) |
| | stu0018 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (112 aa) |
| | stu0019 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (162 aa) |
| | purC | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). (235 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II (FGAM synthetase). (1249 aa) |
| | purM | Phosphoribosylformylglycinamide cyclo-ligase (AIR synthetase). (339 aa) |
| | purN | Phosphoribosylglycinamide (GAR) formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (184 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase (IMP cyclohydrolase). (532 aa) |
| | stu0037 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (104 aa) |
| | stu0038 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (81 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase I (AIR carboxylase, catalytic subunit); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (166 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase II (AIR carboxylase); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (363 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (432 aa) |
| | argS | arginyl-tRNA synthetase. (563 aa) |
| | mutS1 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (852 aa) |
| | trmA | Arsenate reductase family protein; Belongs to the ArsC family. (132 aa) |
| | stu0066 | Conserved hypothetical protein. (183 aa) |
| | stu0067 | ISSpn1, transposase, IS3 family, truncated; Truncated. (49 aa) |
| | stu0068 | ISSpn1, transposase, IS3 family, truncated; Truncated. (77 aa) |
| | stu0069 | ISSpn1, transposase, IS3 family, truncated; Truncated. (87 aa) |
| | stu0071 | Bacteriocin self-immunity protein, putative, truncated; Truncated. (145 aa) |
| | stu0072 | Bacteriocin self-immunity protein, putative, truncated; Truncated. (172 aa) |
| | rpsB | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (255 aa) |
| | clpC | ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family. (816 aa) |
| | trmH | tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (247 aa) |
| | rpsI | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | thiD | Phosphomethylpyrimidine kinase. (253 aa) |
| | cfa | Cyclopropane-fatty-acyl-phospholipid synthase. (399 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa) |
| | stu0136 | MutT/nudix family protein. (148 aa) |
| | defB | Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (204 aa) |
| | rpsO | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | nifU | Conserved hypothetical protein, NifU family protein. (151 aa) |
| | hslO | Heat shock protein, chaperonin, 33 kDa; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. (295 aa) |
| | pgi | Glucose-6-phosphate isomerase. (457 aa) |
| | stu0195 | Conserved hypothetical protein. (241 aa) |
| | uppS | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (249 aa) |
| | groEL | Heat shock protein, chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (539 aa) |
| | stu0206 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (126 aa) |
| | stu0207 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (72 aa) |
| | stu0211 | Ribosomal large subunit pseudouridine synthase, RluD subfamily; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (290 aa) |
| | nusG | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. (179 aa) |
| | stu0217 | Conserved hypothetical protein, truncated; Truncated. (113 aa) |
| | stu0218 | Conserved hypothetical protein, truncated; Truncated. (78 aa) |
| | stu0219 | Transcriptional regulator, DeoR family. (254 aa) |
| | pncB | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (511 aa) |
| | greA | Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (160 aa) |
| | stu0244 | ISSpn1, transposase, IS3 family, truncated; Truncated. (116 aa) |
| | spoU | rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (245 aa) |
| | stu0256 | Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (324 aa) |
| | stu0257 | Conserved hypothetical protein. (173 aa) |
| | rluB | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (255 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (658 aa) |
| | gidB | Glucose-inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (237 aa) |
| | stu0316 | Conserved hypothetical protein. (180 aa) |
| | der | Phosphoglycerate dehydrogenase-related protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (436 aa) |
| | manL | Mannose PTS system component IIAB. (330 aa) |
| | stu0335 | Conserved hypothetical protein, Cof family. (266 aa) |
| | rimP | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (163 aa) |
| | nusA | Transcription termination-antitermination factor; Participates in both transcription termination and antitermination. (395 aa) |
| | stu0343 | Ribosomal protein L7A family. (100 aa) |
| | stu0346 | Hypothetical protein. (97 aa) |
| | stu0347 | Hypothetical protein. (59 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | hpf | Ribosomal subunit interface protein, ribosomal protein S30AE family; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (182 aa) |
| | stu0376 | tRNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (454 aa) |
| | lysC | Aspartate kinase; Belongs to the aspartokinase family. (452 aa) |
| | fabH | beta-ketoacyl-aCP synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (320 aa) |
| | fabK | trans-2-enoyl-ACP reductase II. (321 aa) |
| | fabD | Malonyl CoA-ACP transacylase. (308 aa) |
| | accC | Biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (461 aa) |
| | luxS | Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (160 aa) |
| | fruR | Transcriptional repressor. (248 aa) |
| | fruB | Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (303 aa) |
| | nifS2 | Aminotransferase (class V), putative. (381 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (255 aa) |
| | stu0428 | MutT/nudix family protein. (228 aa) |
| | defA | Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (136 aa) |
| | stu0455 | Methyltransferase, putative. (235 aa) |
| | argD | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (376 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (286 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa) |
| | stu0497 | Conserved hypothetical protein. (285 aa) |
| | glyQ | glycyl-tRNA synthetase alpha subunit. (305 aa) |
| | glyS | glycyl-tRNA synthetase beta subunit. (714 aa) |
| | rluD | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (296 aa) |
| | pyrB | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa) |
| | queA | S-adenosylmethionine-tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (347 aa) |
| | nagB | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (258 aa) |
| | stu0545 | Molybdopterin biosynthesis protein (HesA/MoeB/ThiF family protein), putative. (415 aa) |
| | stu0551 | Phosphorylase, Pnp/Udp family, putative. (256 aa) |
| | rsuA1 | Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family. (239 aa) |
| | stu0555 | Alanine dehydrogenase, truncated; Truncated. (45 aa) |
| | stu0556 | Alanine dehydrogenase, truncated; Truncated. (95 aa) |
| | mvaD | Mevalonate pyrophosphate decarboxylase. (314 aa) |
| | gcaD | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (460 aa) |
| | thrS | threonyl-tRNA synthetase 1; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (648 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (286 aa) |
| | folA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa) |
| | clpX | ATP-dependent Clp protease subunit X; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (408 aa) |
| | engB | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (199 aa) |
| | bcaT | Branched chain amino acid aminotransferase. (340 aa) |
| | rpsA | 30S ribosomal protein S1. (417 aa) |
| | stu0597 | Truncated. (52 aa) |
| | stu0598 | Truncated. (61 aa) |
| | stu0599 | Truncated. (104 aa) |
| | clpE | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. (752 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa) |
| | stu0628 | General stress protein. (121 aa) |
| | eno | 2-phosphoglycerate dehydratase, enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa) |
| | stu0637 | Conserved hypothetical protein. (387 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (225 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (298 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (355 aa) |
| | aroF | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (388 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa) |
| | mip | Macrophage infectivity potentiator-related protein, putative; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (182 aa) |
| | stu0653 | tRNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (453 aa) |
| | stu0698 | Transcriptional regulator; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (157 aa) |
| | stu0700 | Hypothetical protein. (129 aa) |
| | stu0701 | Conserved hypothetical, predicted membrane protein (TMS6). (208 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (940 aa) |
| | stu0736 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (227 aa) |
| | tdk | Thymidine kinase. (198 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (359 aa) |
| | stu0754 | Hypothetical protein, Sua5/YciO/YrdC family protein; Belongs to the SUA5 family. (201 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa) |
| | stu0765 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (72 aa) |
| | stu0766 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (68 aa) |
| | stu0767 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (111 aa) |
| | metE | 5-methyl tetrahydropteroyltriglutamate -- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (762 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (311 aa) |
| | tnpSth1 | ISSth1, transposase (orf2), IS3 family. (289 aa) |
| | stu0800 | Conserved hypothetical protein. (213 aa) |
| | stu0801 | Pyrimidine-nucleoside phosphorylase, truncated; Truncated. (60 aa) |
| | stu0802 | Pyrimidine-nucleoside phosphorylase, truncated; Truncated. (56 aa) |
| | stu0803 | Pyrimidine-nucleoside phosphorylase, truncated; Truncated. (128 aa) |
| | stu0804 | Pyrimidine-nucleoside phosphorylase, truncated; Truncated. (131 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (114 aa) |
| | stu0824 | Conserved hypothetical protein, translation initiation inhibitor protein. (126 aa) |
| | ptpS | 6-pyruvoyl tetrahydrobiopterin synthase, putative. (147 aa) |
| | queF | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (178 aa) |
| | adcA | Zinc (Zn2+) ABC uptake transporter substrate binding protein; Belongs to the bacterial solute-binding protein 9 family. (514 aa) |
| | stu0871 | ISSpn1, transposase, IS3 family, truncated; Truncated. (184 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa) |
| | phnA | Conserved hypothetical protein, PhnA protein. (109 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (527 aa) |
| | tnpSth1-3 | ISSth1, transposase (orf2), IS3 family. (289 aa) |
| | stu0905 | Conserved hypothetical protein, truncated; Truncated. (263 aa) |
| | stu0941 | Phosphorylase, Pnp/Udp family. (254 aa) |
| | pyrF | orotidine-5-Phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (231 aa) |
| | cysD | O-acetylhomoserine sulfhydrylase. (437 aa) |
| | stu0988 | Conserved hypothetical protein, truncated; Truncated. (113 aa) |
| | stu0989 | Conserved hypothetical protein, truncated; Truncated. (122 aa) |
| | psaD | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (164 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (293 aa) |
| | spxA | Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. (137 aa) |
| | lplA | Lipoate-protein ligase. (329 aa) |
| | glgP | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (754 aa) |
| | stu1064 | Truncated. (76 aa) |
| | stu1065 | Truncated. (81 aa) |
| | stu1066 | Truncated. (178 aa) |
| | stu1067 | Truncated. (65 aa) |
| | stu1071 | Conserved hypothetical protein, Cof family, truncated; Truncated. (131 aa) |
| | stu1075 | Hypothetical, predicted membrane protein (TMS6). (191 aa) |
| | deoD | Purine nucleoside phosphorylase (family 1). (236 aa) |
| | stu1114 | Glutamine amidotransferase (GMP synthase), truncated; Truncated. (87 aa) |
| | stu1115 | Glutamine amidotransferase (GMP synthase), truncated; Truncated. (66 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (403 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (226 aa) |
| | cmk | Cytidylate kinase. (226 aa) |
| | mutT | 7,8-dihydro-8-oxoguanine-triphosphatase. (160 aa) |
| | stu1154 | Conserved hypothetical protein, Cof family. (269 aa) |
| | galE2 | UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (337 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (412 aa) |
| | stu1175 | Conserved hypothetical protein. (169 aa) |
| | miaA | tRNA isopentenylpyrophosphate transferase, putative; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (329 aa) |
| | fld | Flavodoxin. (122 aa) |
| | pfk | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (355 aa) |
| | stu1199 | Conserved hypothetical protein; Belongs to the SUA5 family. (261 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (464 aa) |
| | hflX | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (412 aa) |
| | hisK | Histidinol-phosphatase, putative; Belongs to the PHP hydrolase family. HisK subfamily. (247 aa) |
| | stu1234 | N-acetyl-glucosamine catabolism protein, putative. (257 aa) |
| | rmlB | dTDP-glucose-4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (348 aa) |
| | rmlC | dTDP-4-keto-L-rhamnose reductase. (197 aa) |
| | rmlA | Glucose-1-phosphate thymidyl transferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | stu1248 | Conserved hypothetical protein. (262 aa) |
| | nrdH | Glutaredoxin. (74 aa) |
| | nrdE | Ribonucleotide reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (719 aa) |
| | nrdF | Ribonucleotide diphosphate reductase beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (320 aa) |
| | stu1276 | Conserved hypothetical protein. (109 aa) |
| | pdxK | Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. (273 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (358 aa) |
| | sdaB | L-serine dehydratase beta subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family. (237 aa) |
| | sdaA | L-serine dehydratase alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family. (289 aa) |
| | stu1331 | Cytidine/deoxycytidylate deaminase family protein, putative. (149 aa) |
| | tnpSth1-5 | ISSth1, transposase (orf2), IS3 family. (289 aa) |
| | stu1360 | Conserved hypothetical protein; Belongs to the UPF0337 (CsbD) family. (64 aa) |
| | stu1373 | UDP-glucose 4-epimerase, truncated; Truncated. (185 aa) |
| | sthII | Type II restriction-modification system restriction subunit. (1470 aa) |
| | galE1 | UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (333 aa) |
| | galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (388 aa) |
| | stu1405 | ISSpn1, transposase, IS3 family, truncated; Truncated. (62 aa) |
| | gshAB | Conserved hypothetical protein; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine. (754 aa) |
| | rimM | 16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (172 aa) |
| | sunL | RNA-binding protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (443 aa) |
| | stu1433 | Conserved hypothetical protein, Cof family. (271 aa) |
| | stu1434 | Conserved hypothetical protein, Cof family. (264 aa) |
| | stu1446 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (35 aa) |
| | stu1449 | Hypothetical protein. (66 aa) |
| | stu1451 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (212 aa) |
| | stu1452 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (64 aa) |
| | pta | Phosphotransacetylase. (327 aa) |
| | stu1456 | Ribosomal large subunit pseudouridine synthase, RluD subfamily; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (298 aa) |
| | ppnK | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (279 aa) |
| | nifS3 | Aminotransferase (class V), putative. (370 aa) |
| | rgpX2 | Polysaccharide biosynthesis protein, putative rhamnosyl transferase. (336 aa) |
| | stu1487 | Conserved hypothetical protein. (121 aa) |
| | stu1496 | MutT/nudix family protein. (154 aa) |
| | rsuA2 | Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family. (243 aa) |
| | stu1516 | Conserved hypothetical protein. (154 aa) |
| | stu1525 | Conserved hypothetical protein; Belongs to the ArsC family. (117 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (392 aa) |
| | gloA | Glyoxalase I/lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (131 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (325 aa) |
| | folQ | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (119 aa) |
| | folP | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (266 aa) |
| | folE | GTP cyclohydrolase I. (187 aa) |
| | ligA | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (652 aa) |
| | murF | UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-- D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (457 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (260 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (402 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (334 aa) |
| | stu1599 | Conserved hypothetical protein. (96 aa) |
| | stu1603 | Conserved hypothetical protein. (139 aa) |
| | stu1605 | Conserved hypothetical protein. (393 aa) |
| | clpL | ATP-dependent proteinase ATP-binding subunit; Belongs to the ClpA/ClpB family. (699 aa) |
| | stu1620 | Conserved hypothetical protein. (105 aa) |
| | stu1630 | Truncated. (108 aa) |
| | stu1631 | Truncated. (307 aa) |
| | msrA2 | Peptide methionine sulfoxide reductase, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (175 aa) |
| | entB | Pyrazinamidase/nicotinamidase, putative. (183 aa) |
| | pfl | Pyruvate formate-lyase. (769 aa) |
| | tnpSth1-8 | ISSth1, transposase (orf2), IS3 family. (289 aa) |
| | rlmN | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (389 aa) |
| | mraW | S-adenosylmethionine-dependent methyltransferase, putative; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (354 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (267 aa) |
| | recG | ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (672 aa) |
| | aroG1 | Phospho-2-dehydro-3-deoxyheptonate aldolase(DAHP synthatase); Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (343 aa) |
| | aroG2 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (343 aa) |
| | polA | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (879 aa) |
| | stu1772 | Glycoprotein endopeptidase. (253 aa) |
| | stu1786 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (112 aa) |
| | stu1787 | IS861, transposase (orf2), IS3 family, truncated; Truncated. (162 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | ksgA | Dimethyladenosine transferase (rRNA methylation); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (290 aa) |
| | tatD | Deoxyribonuclease, putative. (258 aa) |
| | stu1802 | Conserved hypothetical protein. (150 aa) |
| | trxA1 | Thioredoxin; Belongs to the thioredoxin family. (104 aa) |
| | stu1804 | Conserved hypothetical protein. (260 aa) |
| | tgt | Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on [...] (380 aa) |
| | rplK | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa) |
| | stu1825 | Oxidoreductase, putative, truncated; Truncated. (138 aa) |
| | stu1826 | Oxidoreductase, putative, truncated; Truncated. (72 aa) |
| | tnpSth1-9 | ISSth1, transposase (orf2), IS3 family. (289 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase, putative; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (232 aa) |
| | stu1846 | Transcriptional regulator, putative; Belongs to the sulfur carrier protein TusA family. (75 aa) |
| | proC | Pyrroline carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (256 aa) |
| | stu1900 | Glutamate--cysteine ligase, putative, truncated; Truncated. (201 aa) |
| | stu1901 | Glutamate--cysteine ligase, putative, truncated; Truncated. (62 aa) |
| | stu1902 | Glutamate--cysteine ligase, putative, truncated; Truncated. (48 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (127 aa) |
| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (161 aa) |
| | rpmD | 50S ribosomal protein L30. (60 aa) |
| | rpsE | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (164 aa) |
| | rpsH | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) |
| | rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (180 aa) |
| | rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (217 aa) |
| | rpsS | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (208 aa) |
| | ruvB | Holliday junction DNA helicase, subunit B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (333 aa) |
| | stu1939 | Protein-tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (144 aa) |
| | stu1967 | Conserved hypothetical protein; Belongs to the UPF0246 family. (255 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (583 aa) |
| | stu1972 | Conserved hypothetical protein, truncated; Truncated. (252 aa) |
| | stu1973 | Conserved hypothetical protein, truncated; Truncated. (75 aa) |
| | stu1987 | Conserved hypothetical protein; Belongs to the UPF0337 (CsbD) family. (67 aa) |
| | stu1988 | Conserved hypothetical protein, MutT/nudix family. (183 aa) |
| | stu1989 | Conserved hypothetical protein, truncated; Truncated. (50 aa) |
| | stu1990 | Conserved hypothetical protein, truncated; Truncated. (53 aa) |
| | trmU | tRNA-(5-methylaminomethyl-2-thiouridylate) methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (373 aa) |
| | stu2014 | Conserved hypothetical protein. (125 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (340 aa) |
