STRINGSTRING
murD murD murA murA Bd0141 Bd0141 mrcA mrcA mreB mreB dadA dadA Bd0398 Bd0398 ddlA ddlA nlpD4 nlpD4 dacA dacA mreC mreC Bd2460 Bd2460 rodA rodA mtgA mtgA alr alr ftsZ ftsZ ftsA ftsA ftsQ ftsQ murC murC murG murG ftsW ftsW murD-2 murD-2 mraY mraY murF murF murE murE Bd3213 Bd3213 Bd3214 Bd3214 mraW mraW Bd3217 Bd3217 murB murB Bd3243 Bd3243 dacB dacB mrcB mrcB pbpB pbpB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (418 aa)
murAUDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (414 aa)
Bd0141Penicillin-binding protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. Belongs to the glycosyltransferase 51 family. (277 aa)
mrcAPenicillin-binding protein 1A; InterPro: Penicillin binding protein transpeptidase domain, ponA, penicillin-binding protein 1A [EC: 3.4.-.-]; hypothetical protein. (898 aa)
mreBInterPro: Cell shape determining protein MreB/Mrl; hypothetical protein. (363 aa)
dadAD-amino acid dehydrogenase small subunit; hypothetical protein. (415 aa)
Bd0398Probable cell wall-binding protein, associated metalloendopeptidase; hypothetical protein. (334 aa)
ddlAD-alanine-D-alanine ligase; Cell wall formation. (365 aa)
nlpD4Membrane proteins related to metalloendopeptidases. (193 aa)
dacADacA protein; InterPro: D-alanyl-D-alanine carboxypeptidase 1 (S11) family; hypothetical protein. (286 aa)
mreCRod shape-determining protein MreC; InterPro: Type I antifreeze protein; hypothetical protein. (381 aa)
Bd2460InterPro: Penicillin binding protein transpeptidase domain, COG0768 Cell division protein FtsI/penicillin-binding protein 2; hypothetical protein. (661 aa)
rodARod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (374 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (250 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (402 aa)
ftsZCell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (552 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (418 aa)
ftsQCell division protein. (248 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (453 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (357 aa)
ftsWInterPro: Cell cycle proteins; hypothetical protein; Belongs to the SEDS family. (380 aa)
murD-2UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (462 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (358 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (473 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
Bd3213Cell division protein. (660 aa)
Bd3214Putative histidine kinase. (111 aa)
mraWS-adenosyl-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (328 aa)
Bd3217Hypothetical protein predicted by Glimmer/Critica. (342 aa)
murBUDP-N-acetylpyruvoylglucosamine reductase; Cell wall formation. (336 aa)
Bd3243Membrane-bound lytic murein transglycosylase, putative; InterPro: SLT domain; hypothetical protein. (400 aa)
dacBD-Ala-D-Ala carboxypeptidase 3 (S13) family; dacB; D-alanyl-D-alanine carboxypeptidase; hypothetical protein. (436 aa)
mrcBPenicillin-binding protein 1B; InterPro: Penicillin binding protein transpeptidase domain; hypothetical protein. (790 aa)
pbpBInterPro: Penicillin binding protein transpeptidase domain; hypothetical protein. (444 aa)
Your Current Organism:
Bdellovibrio bacteriovorus HD100
NCBI taxonomy Id: 264462
Other names: B. bacteriovorus HD100, Bdellovibrio bacteriovorus DSM 50701, Bdellovibrio bacteriovorus str. HD100, Bdellovibrio bacteriovorus strain HD100
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.