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yfhD yfhD Bd3627 Bd3627 purF purF Bd3073 Bd3073 Bd3792 Bd3792 murG murG ftsW ftsW Bd3213 Bd3213 Bd3218 Bd3218 hpt hpt Bd2859 Bd2859 mrcB mrcB Bd3831 Bd3831 pdp pdp pnp-2 pnp-2 Bd3815 Bd3815 lgt-2 lgt-2 hprT hprT mltG mltG Bd0141 Bd0141 mrcA mrcA pbpC pbpC Bd0314 Bd0314 mltD mltD Bd0616 Bd0616 Bd0618 Bd0618 Bd0691 Bd0691 capM1 capM1 aprT aprT pyrE pyrE lgt lgt Bd1123 Bd1123 mltD-2 mltD-2 Bd1413 Bd1413 Bd1440 Bd1440 lpxB lpxB Bd1503 Bd1503 rfaF rfaF upp upp Bd1561 Bd1561 Bd1669 Bd1669 Bd1672 Bd1672 hisH hisH hisF hisF Bd1696 Bd1696 Bd1868 Bd1868 tgt tgt queA queA Bd2264 Bd2264 Bd2366 Bd2366 kdtA kdtA rodA rodA Bd2462 Bd2462 Bd2738 Bd2738 nadC nadC mtgA mtgA
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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yfhDPutative periplasmic binding transport protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (474 aa)
Bd3627Conserved hypothetical protein related glycosyltransferases. (604 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (479 aa)
Bd3073Hypothetical protein predicted by Glimmer/Critica. (442 aa)
Bd3792InterPro: DUF152; hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (232 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (357 aa)
ftsWInterPro: Cell cycle proteins; hypothetical protein; Belongs to the SEDS family. (380 aa)
Bd3213Cell division protein. (660 aa)
Bd3218Hypothetical protein predicted by Glimmer/Critica. (262 aa)
hptHypoxanthine-guanine phosphoribosyltransferase homologue; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa)
Bd2859Conserved hypothetical protein; InterPro: Dolichyl-phosphate-mannose-protein mannosyltransferase; hypothetical protein. (525 aa)
mrcBPenicillin-binding protein 1B; InterPro: Penicillin binding protein transpeptidase domain; hypothetical protein. (790 aa)
Bd3831Conserved hypothetical protein; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family. (406 aa)
pdpPyrimidine-nucleoside phosphorylase. (439 aa)
pnp-2Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (280 aa)
Bd3815InterPro: Phosphoribosyl transferase; hypothetical protein. (441 aa)
lgt-2Putative prolipoprotein diacylglycerol transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (249 aa)
hprTInterPro: Phosphoribosyl transferase, Hypoxanthine-guanine phosphoribosyltransferase, YacA-like protein; hypothetical protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (172 aa)
mltGEndolytic murein transglycosylase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (360 aa)
Bd0141Penicillin-binding protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. Belongs to the glycosyltransferase 51 family. (277 aa)
mrcAPenicillin-binding protein 1A; InterPro: Penicillin binding protein transpeptidase domain, ponA, penicillin-binding protein 1A [EC: 3.4.-.-]; hypothetical protein. (898 aa)
pbpCBifunctional penicillin-binding protein; InterPro: Penicillin binding protein transpeptidase domain; hypothetical protein. (672 aa)
Bd0314Hypothetical protein predicted by Glimmer/Critica. (254 aa)
mltDMembrane-bound lytic murein transglycosylase D precursor, Regulatory protein dniR; hypothetical protein. (394 aa)
Bd0616Putative lipopolysaccharide heptosyltransferase-I; InterPro: Glycosyltransferase family 9; hypothetical protein. (502 aa)
Bd0618Putative lipopolysaccharide biosynthesis protein; InterPro: Glycosyltransferase family 9; hypothetical protein. (484 aa)
Bd0691Unnamed protein product; CDS. (345 aa)
capM1Putative glycosyltransferase; LPS biosynthesis RFBU related protein; hypothetical protein. (419 aa)
aprTAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (165 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (179 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (352 aa)
Bd1123Putative membrane-bound mannosyltransferase. (506 aa)
mltD-2Membrane-bound lytic murein transglycosylase D precursor; hypothetical protein. (526 aa)
Bd1413Hypothetical protein predicted by Glimmer/Critica. (271 aa)
Bd1440Hypothetical protein predicted by Glimmer/Critica. (266 aa)
lpxBLipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa)
Bd1503Putative heptosyltransferase. (381 aa)
rfaFADP-heptose:LPS heptosyltransferase II; InterPro: Glycosyltransferase family 9, ADP-heptose--LPS heptosyltransferase II; hypothetical protein. (363 aa)
uppUracil phosphoribosyltransferase; InterPro: Phosphoribosyl transferase; hypothetical protein; Belongs to the UPRTase family. (210 aa)
Bd1561Putative glycosyl transferase. (231 aa)
Bd1669Similar to Melittin resistance protein; hypothetical protein. (487 aa)
Bd1672Putative N-acetylglucosaminyltransferase. (275 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa)
Bd1696Putative glycosyltransferase. (405 aa)
Bd1868Putative glycosyltransferase; InterPro: Glycosyl transferases group 1; hypothetical protein. (388 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (383 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (346 aa)
Bd2264Hypothetical protein predicted by Glimmer/Critica. (390 aa)
Bd2366Heptosyltransferase; InterPro: Glycosyltransferase family 9; hypothetical protein. (348 aa)
kdtA3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (430 aa)
rodARod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (374 aa)
Bd2462Soluble lytic murein transglycosylase and related regulatory proteins(some contain LysM/invasin domains); hypothetical protein. (239 aa)
Bd2738Hypothetical protein predicted by Glimmer/Critica. (479 aa)
nadCNadC protein; InterPro: Nicotinate-nucleotide pyrophosphorylase; hypothetical protein; Belongs to the NadC/ModD family. (274 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (250 aa)
Your Current Organism:
Bdellovibrio bacteriovorus HD100
NCBI taxonomy Id: 264462
Other names: B. bacteriovorus HD100, Bdellovibrio bacteriovorus DSM 50701, Bdellovibrio bacteriovorus str. HD100, Bdellovibrio bacteriovorus strain HD100
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