STRINGSTRING
asd asd lys1 lys1 PRU_0088 PRU_0088 PRU_0136 PRU_0136 ispH ispH rfbD rfbD queF queF fabG fabG hisD hisD PRU_0413 PRU_0413 PRU_0435 PRU_0435 PRU_0436 PRU_0436 PRU_0452 PRU_0452 PRU_0457 PRU_0457 msrA msrA PRU_0488 PRU_0488 PRU_0505 PRU_0505 pyrK pyrK pyrD pyrD PRU_0549 PRU_0549 PRU_0550 PRU_0550 ilvC ilvC PRU_0572 PRU_0572 PRU_0573 PRU_0573 murB murB PRU_0612 PRU_0612 PRU_0672 PRU_0672 hprA hprA gltA_1 gltA_1 PRU_0721 PRU_0721 leuB leuB PRU_0735 PRU_0735 rnfB rnfB rnfC rnfC rnfD rnfD PRU_0807 PRU_0807 rnfA rnfA PRU_0965 PRU_0965 PRU_0969 PRU_0969 PRU_0982 PRU_0982 PRU_1014 PRU_1014 PRU_1015 PRU_1015 guaB guaB thrA thrA PRU_1024 PRU_1024 PRU_1025 PRU_1025 serA serA cobKD cobKD PRU_1097 PRU_1097 PRU_1116 PRU_1116 PRU_1125 PRU_1125 panE panE PRU_1147 PRU_1147 PRU_1149 PRU_1149 folD folD queH queH tyrA tyrA PRU_1181 PRU_1181 PRU_1207 PRU_1207 gdhA gdhA nifJ nifJ pflA pflA nqrF nqrF nqrE nqrE nqrD nqrD nqrC nqrC nqrB nqrB nqrA nqrA PRU_1261 PRU_1261 cydB cydB PRU_1263 PRU_1263 folA folA PRU_1287 PRU_1287 PRU_1288 PRU_1288 PRU_1296 PRU_1296 PRU_1313 PRU_1313 PRU_1328 PRU_1328 PRU_1347 PRU_1347 trxB trxB nrdD_1 nrdD_1 rbr rbr fcl fcl PRU_1415 PRU_1415 PRU_1473 PRU_1473 PRU_1478 PRU_1478 PRU_1511 PRU_1511 PRU_1536 PRU_1536 PRU_1539 PRU_1539 PRU_1542 PRU_1542 PRU_1561 PRU_1561 PRU_1598 PRU_1598 PRU_1615 PRU_1615 PRU_1638 PRU_1638 PRU_1646 PRU_1646 PRU_1669 PRU_1669 gap gap PRU_1692 PRU_1692 PRU_1694 PRU_1694 PRU_1697 PRU_1697 metF metF nuoN nuoN PRU_1713 PRU_1713 PRU_1714 PRU_1714 nuoK nuoK PRU_1716 PRU_1716 PRU_1717 PRU_1717 nuoH nuoH PRU_1719 PRU_1719 nuoB nuoB nuoA nuoA sodB sodB PRU_1755 PRU_1755 PRU_1769 PRU_1769 PRU_1814 PRU_1814 PRU_1859 PRU_1859 trx trx gltD gltD gltA_2 gltA_2 nadB nadB PRU_2001 PRU_2001 PRU_2034 PRU_2034 etfA etfA etfB etfB PRU_2044 PRU_2044 gcvP2 gcvP2 gcvP1 gcvP1 PRU_2053 PRU_2053 ald ald PRU_2084 PRU_2084 PRU_2156 PRU_2156 PRU_2158 PRU_2158 argC argC proC proC proA proA PRU_2219 PRU_2219 PRU_2267 PRU_2267 idnO idnO PRU_2342 PRU_2342 PRU_2379 PRU_2379 PRU_2389 PRU_2389 ribD ribD bcp bcp PRU_2431 PRU_2431 PRU_2432 PRU_2432 PRU_2433 PRU_2433 dapB dapB PRU_2462 PRU_2462 PRU_2465 PRU_2465 PRU_2500 PRU_2500 PRU_2565 PRU_2565 PRU_2577 PRU_2577 PRU_2579 PRU_2579 PRU_2583 PRU_2583 PRU_2587 PRU_2587 PRU_2632 PRU_2632 PRU_2640 PRU_2640 PRU_2725 PRU_2725 hemN hemN hemG hemG PRU_2787 PRU_2787 PRU_2788 PRU_2788 PRU_2796 PRU_2796 PRU_2799 PRU_2799 PRU_2829 PRU_2829 PRU_2830 PRU_2830 PRU_2835 PRU_2835 PRU_2840 PRU_2840 PRU_2842 PRU_2842 nrdD_2 nrdD_2 nrdG_2 nrdG_2 ispG ispG dxr dxr
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
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gene neighborhood
gene fusions
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asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (337 aa)
lys1Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. (412 aa)
PRU_0088Octopine/opine/tauropine dehydrogenase-like protein; Identified by similarity to SP:Q44297; match to protein family HMM PF01210; match to protein family HMM PF02317. (340 aa)
PRU_0136Lyase domain protein; Identified by similarity to SP:Q46267. (86 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (291 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (285 aa)
queFGTP cyclohydrolase family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (153 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
PRU_0413Sulfatase-activating enzyme, ChuR family; Identified by similarity to SP:Q02550; match to protein family HMM PF04055; match to protein family HMM TIGR03942. (399 aa)
PRU_0435CDP-D-glucose-4,6-dehydratase; Identified by similarity to GB:AAA88700.1; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR02622. (358 aa)
PRU_0436Nucleoside diphosphate sugar epimerase family protein; Identified by match to protein family HMM PF01370. (301 aa)
PRU_0452Putative polysaccharide biosynthesis protein; Identified by similarity to SP:Q8X7P7; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993. (337 aa)
PRU_0457Oxidoreductase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894. (330 aa)
msrAmethionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (173 aa)
PRU_0488Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (251 aa)
PRU_0505Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243. (159 aa)
pyrKDihydroorotate oxidase, electron transfer subunit; Identified by similarity to SP:P25983; match to protein family HMM PF00175. (248 aa)
pyrDDihydroorotate oxidase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (301 aa)
PRU_0549Oxidoreductase, short chain dehydrogenase/reductase family; Identified by similarity to GB:AAO79601.1; match to protein family HMM PF00106. (235 aa)
PRU_0550Conserved hypothetical protein; Identified by similarity to GB:AAM44404.1. (148 aa)
ilvCKetol-acid reductoisomerase; Identified by match to protein family HMM PF01450; match to protein family HMM PF07991; match to protein family HMM TIGR00465. (346 aa)
PRU_0572Radical SAM domain protein; Identified by match to protein family HMM PF04055. (287 aa)
PRU_0573Conserved hypothetical protein; Identified by similarity to GB:AAN25509.1; match to protein family HMM PF01871; match to protein family HMM PF01875; match to protein family HMM TIGR00296; Belongs to the MEMO1 family. (464 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (333 aa)
PRU_0612Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (375 aa)
PRU_0672Thioredoxin domain protein; Identified by similarity to GB:AAQ66661.1. (190 aa)
hprAGlycerate dehydrogenase (NADH-dependent); Identified by similarity to SP:Q59516; match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (299 aa)
gltA_1Glutamate synthase (NADPH), homotetrameric; Identified by match to protein family HMM PF00070; match to protein family HMM PF00175; match to protein family HMM PF07992; match to protein family HMM TIGR01316. (786 aa)
PRU_0721Shikimate dehydrogenase; Identified by similarity to SP:P54374; match to protein family HMM PF01488; match to protein family HMM PF08501. (248 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. (353 aa)
PRU_0735Identified by match to protein family HMM PF01232; match to protein family HMM PF08125. (528 aa)
rnfBElectron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (293 aa)
rnfCElectron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (456 aa)
rnfDElectron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (330 aa)
PRU_0807Electron transport complex, RnfABCDGE type, G subunit; Identified by match to protein family HMM PF04205; match to protein family HMM TIGR01947. (193 aa)
rnfAElectron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (200 aa)
PRU_0965Conserved hypothetical protein; Identified by similarity to GB:AAO78428.1. (796 aa)
PRU_0969Identified by match to protein family HMM PF00881. (165 aa)
PRU_0982Rubredoxin/rubrerythrin domain protein; Identified by match to protein family HMM PF00301; match to protein family HMM PF02915. (185 aa)
PRU_1014Thioredoxin domain protein; Identified by similarity to SP:P35160; match to protein family HMM PF00578; match to protein family HMM PF08534. (331 aa)
PRU_1015Conserved hypothetical protein TIGR00726; Identified by similarity to GB:AAM71274.1; match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family. (248 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa)
thrAAspartate kinase/homoserine dehydrogenase; Identified by similarity to SP:P00561; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. (810 aa)
PRU_1024Putative indolepyruvate oxidoreductase, beta subunit; Identified by similarity to SP:O07836; match to protein family HMM PF01558. (190 aa)
PRU_1025Putative indolepyruvate oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (533 aa)
serAD-phosphoglycerate dehydrogenase; Identified by similarity to GB:BAD00050.1; match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (305 aa)
cobKDPrecorrin-6x reductase/cobalamin biosynthetic protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (589 aa)
PRU_1097Conserved hypothetical protein; Identified by similarity to SP:Q58156; match to protein family HMM PF02915. (134 aa)
PRU_1116Putative arylsulfatase-activating enzyme AtsB; Identified by match to protein family HMM PF04055. (427 aa)
PRU_1125Identified by match to protein family HMM PF02525; match to protein family HMM PF03358. (171 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (305 aa)
PRU_1147Keto/oxoacid ferredoxin oxidoreductase, gamma subunit; Identified by match to protein family HMM PF01558. (181 aa)
PRU_1149Putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GB:AAC38211.1; match to protein family HMM PF01855; match to protein family HMM PF02780. (361 aa)
folDBifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa)
queHConserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (210 aa)
tyrAPrephenate dehydrogenase; Identified by match to protein family HMM PF02153. (264 aa)
PRU_1181Conserved hypothetical protein; Identified by similarity to PIR:G71368. (99 aa)
PRU_1207Identified by match to protein family HMM PF00881. (175 aa)
gdhAGlutamate dehydrogenase, NADP-specific; Identified by similarity to SP:P95544; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (445 aa)
nifJPyruvate:ferredoxin (flavodoxin) oxidoreductase; Identified by similarity to GB:CAA70873.1; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02175; match to protein family HMM TIGR02176. (1191 aa)
pflAPyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (245 aa)
nqrFNADH:ubiquinone oxidoreductase, F subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (422 aa)
nqrENADH:ubiquinone oxidoreductase, E subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (208 aa)
nqrDNADH:ubiquinone oxidoreductase, D subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (207 aa)
nqrCNADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (222 aa)
nqrBNADH:ubiquinone oxidoreductase, B subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (386 aa)
nqrANADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (444 aa)
PRU_1261Putative cytochrome d ubiquinol oxidase, subunit I; Identified by similarity to SP:Q09049; match to protein family HMM PF01654; Belongs to the cytochrome ubiquinol oxidase subunit 1 family. (510 aa)
cydBCytochrome d ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF02322. (382 aa)
PRU_1263Putative thiol-disulfide oxidoreductase; Identified by similarity to SP:P35160; match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534. (161 aa)
folADihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (171 aa)
PRU_1287Conserved domain protein; Identified by similarity to GB:AAO77252.1. (196 aa)
PRU_1288Identified by match to protein family HMM PF00881; Belongs to the flavin oxidoreductase frp family. (254 aa)
PRU_1296Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037. (274 aa)
PRU_1313UDP-glucose 6-dehydrogenase; Identified by similarity to SP:O32271; match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF02737; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026. (439 aa)
PRU_1328Iron-sulfur cluster-binding protein. (320 aa)
PRU_1347Glutathione peroxidase; Identified by similarity to PIR:S33618; match to protein family HMM PF00255; Belongs to the glutathione peroxidase family. (206 aa)
trxBThioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. (310 aa)
nrdD_1Anaerobic ribonucleoside-triphosphate reductase; Identified by similarity to SP:P28903; match to protein family HMM PF03477; match to protein family HMM TIGR02827. (701 aa)
rbrRubrerythrin; Identified by match to protein family HMM PF00301; match to protein family HMM PF02915. (180 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (389 aa)
PRU_1415Putative thiol:disulfide interchange protein; Identified by match to protein family HMM PF02683. (653 aa)
PRU_1473Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248. (323 aa)
PRU_1478Thioredoxin family protein; Identified by similarity to GB:BAC81190.1; match to protein family HMM PF00578. (171 aa)
PRU_1511Conserved domain protein; Identified by similarity to GB:CAC87154.1. (164 aa)
PRU_1536Radical SAM domain protein; Identified by match to protein family HMM PF04055. (278 aa)
PRU_1539Conserved hypothetical protein; Identified by similarity to GB:AAL62855.1. (428 aa)
PRU_1542Polysaccharide biosynthesis protein; Identified by similarity to GB:AAC18831.1; similarity to GB:AAD50494.1; match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993. (353 aa)
PRU_1561Putative 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by similarity to SP:P19624; match to protein family HMM PF04166; Belongs to the PdxA family. (344 aa)
PRU_1598Fibronectin type III domain protein; Identified by match to protein family HMM PF00041. (520 aa)
PRU_1615Putative lipoprotein; Identified by similarity to GB:AAO75346.1. (257 aa)
PRU_1638Conserved hypothetical protein; Identified by similarity to GB:AAM04131.1; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF07992. (350 aa)
PRU_1646Tagaturonate reductase; Identified by similarity to SP:P24214; match to protein family HMM PF01232; match to protein family HMM PF08125. (479 aa)
PRU_1669Conserved hypothetical protein; Identified by similarity to GB:AAO36036.1; match to protein family HMM PF00578; match to protein family HMM PF08534. (190 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
PRU_1692Glycerol-3-phosphate dehydrogenase; Identified by match to protein family HMM PF01210; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa)
PRU_1694NADPH-dependent reductase; Identified by match to protein family HMM PF03358. (181 aa)
PRU_1697Identified by match to protein family HMM PF00258; match to protein family HMM PF00753. (388 aa)
metFMethylenetetrahydrofolate reductase (NAD(P)H); Identified by similarity to GB:AAF64321.1; match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. (321 aa)
nuoNProton-translocating NADH-quinone oxidoreductase, N subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (483 aa)
PRU_1713Proton-translocating NADH-quinone oxidoreductase, M subunit; Identified by match to protein family HMM PF00361; match to protein family HMM TIGR01972. (506 aa)
PRU_1714Proton-translocating NADH-quinone oxidoreductase, L subunit; Identified by match to protein family HMM PF00361; match to protein family HMM PF00662; match to protein family HMM TIGR01974. (662 aa)
nuoKPutative proton-translocating NADH-quinone oxidoreductase, K subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (102 aa)
PRU_1716Putative proton-translocating NADH-quinone oxidoreductase, J subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (171 aa)
PRU_1717Putative proton-translocating NADH-quinone oxidoreductase, I subunit; Identified by match to protein family HMM PF00037. (181 aa)
nuoHPutative proton-translocating NADH-quinone oxidoreductase, H subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (362 aa)
PRU_1719Putative proton-translocating NADH-quinone oxidoreductase, D subunit; Identified by match to protein family HMM PF00329; match to protein family HMM PF00346. (521 aa)
nuoBPutative proton-translocating NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (263 aa)
nuoAPutative proton-translocating NADH-quinone oxidoreductase, A subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (116 aa)
sodBSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (194 aa)
PRU_1755NAD dependent epimerase/dehydratase family protein; Identified by similarity to SP:Q8X7P7; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993. (337 aa)
PRU_1769UDP-glucose 6-dehydrogenase; Identified by similarity to SP:O32271; match to protein family HMM PF00070; match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF02737; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026. (437 aa)
PRU_1814Dihydroorotate oxidase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01180; match to protein family HMM TIGR01037. (398 aa)
PRU_1859Putative membrane protein; Identified by similarity to GB:AAQ65806.1; match to protein family HMM PF07681. (386 aa)
trxThioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family. (104 aa)
gltDGlutamate synthase, NADH/NADPH, small subunit; Identified by match to protein family HMM PF01266; match to protein family HMM PF07992; match to protein family HMM TIGR01317. (469 aa)
gltA_2Glutamate synthase (NADPH), large subunit; Identified by similarity to SP:P39812; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. (1497 aa)
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (528 aa)
PRU_2001Putative redox protein; Identified by match to protein family HMM PF09719; match to protein family HMM TIGR01909. (159 aa)
PRU_2034acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028. (575 aa)
etfAElectron transfer flavoprotein, alpha subunit; Identified by match to protein family HMM PF00766; match to protein family HMM PF01012. (341 aa)
etfBElectron transfer flavoprotein, beta subunit; Identified by match to protein family HMM PF01012. (290 aa)
PRU_2044Dihydrolipoyl dehydrogenase; Identified by similarity to GB:AAA21748.1; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (428 aa)
gcvP2Glycine dehydrogenase (decarboxylating), subunit 2; Identified by similarity to SP:Q8RCW2. (469 aa)
gcvP1Glycine dehydrogenase (decarboxylating), subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (438 aa)
PRU_2053Conserved domain protein; Identified by similarity to SP:P06544; match to protein family HMM PF00578. (484 aa)
aldAlanine dehydrogenase; Identified by similarity to SP:P17556; match to protein family HMM PF01262; match to protein family HMM PF01488; match to protein family HMM PF02826; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. (367 aa)
PRU_2084Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P94316; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (445 aa)
PRU_2156Conserved hypothetical protein; Identified by similarity to GB:AAO78428.1. (781 aa)
PRU_2158Putative malate dehydrogenase; Identified by similarity to SP:P10584; match to protein family HMM PF00056; match to protein family HMM PF02866; Belongs to the LDH/MDH superfamily. (328 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (321 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (259 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (413 aa)
PRU_2219Putative lipoprotein. (218 aa)
PRU_2267Putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GB:BAB21494.1; match to protein family HMM PF01855; match to protein family HMM TIGR03710. (610 aa)
idnOGluconate 5-dehydrogenase; Identified by similarity to SP:P39345; match to protein family HMM PF00106. (267 aa)
PRU_2342Thioredoxin domain protein; Identified by similarity to SP:P52230; match to protein family HMM PF00578; match to protein family HMM PF08534. (403 aa)
PRU_2379Conserved hypothetical protein; Identified by similarity to SP:Q97DZ9; Belongs to the UPF0311 family. (162 aa)
PRU_2389Putative lipoprotein; Identified by similarity to GB:AAO77951.1; match to protein family HMM PF00578. (333 aa)
ribDRiboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00326. (307 aa)
bcpThioredoxin-dependent thiol peroxidase Bcp; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534. (152 aa)
PRU_2431Succinate dehydrogenase/fumarate reductase, iron-sulfur protein; Identified by similarity to GB:AAO42601.1; match to protein family HMM TIGR00384. (252 aa)
PRU_2432Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01811. (659 aa)
PRU_2433Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; Identified by similarity to GB:AAO42599.1; match to protein family HMM TIGR02046. (229 aa)
dapBDihydrodipicolinate reductase; Identified by match to protein family HMM PF01113; match to protein family HMM PF03447; match to protein family HMM PF05173; match to protein family HMM TIGR00036; Belongs to the DapB family. (238 aa)
PRU_2462Conserved hypothetical protein; Identified by similarity to GB:AAO76785.1; match to protein family HMM PF01210; match to protein family HMM PF01408; match to protein family HMM PF03807. (256 aa)
PRU_2465Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (315 aa)
PRU_2500Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037. (494 aa)
PRU_2565Rubredoxin; Identified by similarity to SP:P00268; match to protein family HMM PF00301. (51 aa)
PRU_2577FMN reductase, NADPH-dependent domain protein; Identified by match to protein family HMM PF02525; match to protein family HMM PF03358. (189 aa)
PRU_2579Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243. (139 aa)
PRU_2583Conserved hypothetical protein; Identified by similarity to GB:AAM05241.1; match to protein family HMM PF02525; match to protein family HMM PF03358. (233 aa)
PRU_2587Putative membrane protein; Identified by match to protein family HMM PF04171; match to protein family HMM PF04235. (373 aa)
PRU_2632Putative lipoprotein; Identified by similarity to GB:AAQ66246.1; match to protein family HMM PF00578; match to protein family HMM PF08534. (384 aa)
PRU_2640Conserved domain protein; Identified by similarity to GB:CAF30361.1. (241 aa)
PRU_2725Thioredoxin domain protein; Identified by similarity to SP:P35160; match to protein family HMM PF00578; match to protein family HMM PF08534. (362 aa)
hemNCoproporphyrinogen dehydrogenase; Identified by similarity to SP:P32131; match to protein family HMM PF04055; match to protein family HMM PF06969; match to protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (454 aa)
hemGProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (451 aa)
PRU_2787Identified by match to protein family HMM PF00881. (194 aa)
PRU_2788Identified by match to protein family HMM PF00255; Belongs to the glutathione peroxidase family. (181 aa)
PRU_2796Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (164 aa)
PRU_2799Conserved domain protein; Identified by similarity to GB:CAE78545.1. (570 aa)
PRU_2829Hypothetical protein; Identified by glimmer; putative. (422 aa)
PRU_2830Hypothetical protein; Identified by glimmer; putative. (411 aa)
PRU_2835Putative thiol-disulfide oxidoreductase; Identified by similarity to SP:P35160; match to protein family HMM PF00578; match to protein family HMM PF08534. (176 aa)
PRU_2840Oxidoreductase, zinc-binding dehydrogenase family; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240. (338 aa)
PRU_2842Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248. (316 aa)
nrdD_2Anaerobic ribonucleoside-triphosphate reductase; Identified by similarity to SP:P28903; match to protein family HMM PF03477; match to protein family HMM TIGR02487. (746 aa)
nrdG_2Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (165 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (461 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa)
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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