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PRU_0157 PRU_0157 glkA glkA PRU_0395 PRU_0395 galM_1 galM_1 galM_2 galM_2 fbp fbp pyk pyk pfp pfp PRU_1017 PRU_1017 PRU_1071 PRU_1071 eno eno PRU_1149 PRU_1149 pfkA pfkA nifJ nifJ ppdK ppdK pgk pgk gap gap PRU_1688 PRU_1688 PRU_1689 PRU_1689 PRU_1690 PRU_1690 pgi pgi tpiA tpiA PRU_2044 PRU_2044 fba fba PRU_2205 PRU_2205 PRU_2267 PRU_2267 PRU_2268 PRU_2268 pckA pckA gpmI gpmI PRU_2364 PRU_2364 agp agp
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRU_0157CoA-binding domain protein; Identified by match to protein family HMM PF02629. (686 aa)
glkAGlucokinase; Identified by similarity to SP:P40184; match to protein family HMM PF00480. (327 aa)
PRU_0395ROK family protein; Identified by match to protein family HMM PF00480. (274 aa)
galM_1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (384 aa)
galM_2Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (363 aa)
fbpFructose-1,6-bisphosphatase; Identified by similarity to GB:CAB16056.1; match to protein family HMM PF06874. (657 aa)
pykPyruvate kinase; Identified by similarity to SP:P14178; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (481 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (545 aa)
PRU_1017Putative homoserine kinase; Assignment based on phylogenetic profiling and gene location; identified by match to protein family HMM PF01676; match to protein family HMM TIGR00306; match to protein family HMM TIGR02535. (414 aa)
PRU_1071Identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880. (581 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
PRU_1149Putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GB:AAC38211.1; match to protein family HMM PF01855; match to protein family HMM PF02780. (361 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)
nifJPyruvate:ferredoxin (flavodoxin) oxidoreductase; Identified by similarity to GB:CAA70873.1; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02175; match to protein family HMM TIGR02176. (1191 aa)
ppdKPyruvate, phosphate dikinase; Identified by similarity to SP:P22983; match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828; Belongs to the PEP-utilizing enzyme family. (906 aa)
pgkPhosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (423 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
PRU_1688ROK family protein; Identified by match to protein family HMM PF00480. (326 aa)
PRU_1689Transcriptional regulator, ROK family; Identified by match to protein family HMM PF00480. (332 aa)
PRU_1690ROK family protein; Identified by match to protein family HMM PF00480. (326 aa)
pgiGlucose-6-phosphate isomerase; Identified by similarity to SP:P80860; match to protein family HMM PF00342; Belongs to the GPI family. (449 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
PRU_2044Dihydrolipoyl dehydrogenase; Identified by similarity to GB:AAA21748.1; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (428 aa)
fbaFructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. (333 aa)
PRU_2205AMP-binding enzyme; Identified by match to protein family HMM PF00501. (550 aa)
PRU_2267Putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GB:BAB21494.1; match to protein family HMM PF01855; match to protein family HMM TIGR03710. (610 aa)
PRU_2268Putative keto/oxoacid ferredoxin oxidoreductase, beta subunit; Identified by similarity to GB:BAB21495.1; match to protein family HMM PF02775. (334 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa)
PRU_2364Identified by match to protein family HMM PF00480. (329 aa)
agpGlucose-1-phosphatase; Identified by similarity to SP:P19926; match to protein family HMM PF00328. (469 aa)
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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