STRINGSTRING
A0A443HHN7 A0A443HHN7 A0A443HHT9 A0A443HHT9 A0A443HI28 A0A443HI28 A0A443HIK2 A0A443HIK2 A0A443HJ32 A0A443HJ32 A0A443HJ63 A0A443HJ63 A0A443HJP4 A0A443HJP4 A0A443HLT9 A0A443HLT9 A0A443HLY2 A0A443HLY2 A0A443HM03 A0A443HM03 A0A443HMC8 A0A443HMC8 A0A443HMQ5 A0A443HMQ5 A0A443HN79 A0A443HN79 A0A443HN84 A0A443HN84 A0A443HNH3 A0A443HNH3 A0A443HNI1 A0A443HNI1 A0A443HNU5 A0A443HNU5 A0A443HNZ0 A0A443HNZ0 A0A443HP83 A0A443HP83 A0A443HPF7 A0A443HPF7 A0A443HPI3 A0A443HPI3 A0A443HPV3 A0A443HPV3 A0A443HPZ4 A0A443HPZ4 A0A443HQ10 A0A443HQ10 A0A443HQQ1 A0A443HQQ1 A0A443HR83 A0A443HR83 A0A443HRV3 A0A443HRV3 A0A443HRY0 A0A443HRY0 A0A443HS20 A0A443HS20 A0A443HSG1 A0A443HSG1 A0A443HSS5 A0A443HSS5 A0A443HSW2 A0A443HSW2 A0A443HT57 A0A443HT57 A0A443HTD0 A0A443HTD0 A0A443HTE7 A0A443HTE7 A0A443HUP9 A0A443HUP9 A0A443HUW1 A0A443HUW1 A0A443HW48 A0A443HW48 A0A443HW53 A0A443HW53 A0A443HWS8 A0A443HWS8 A0A443HWZ2 A0A443HWZ2 A0A443HZN8 A0A443HZN8 A0A443HZY2 A0A443HZY2 A0A443I017 A0A443I017 A0A443I0N3 A0A443I0N3 A0A443I0U3 A0A443I0U3 A0A443I0Z4 A0A443I0Z4 A0A443I187 A0A443I187 A0A443I1S7 A0A443I1S7 A0A443I230 A0A443I230 A0A443I254 A0A443I254 A0A443I2I4 A0A443I2I4 A0A443I3H1 A0A443I3H1 A0A443I4K7 A0A443I4K7 A0A443I4T4 A0A443I4T4 A0A443I512 A0A443I512 A0A443I5V4 A0A443I5V4 A0A443I5W3 A0A443I5W3 A0A443I655 A0A443I655 A0A443I7T0 A0A443I7T0 SLX1 SLX1 A0A443I8J7 A0A443I8J7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A443HHN7DNA polymerase alpha/epsilon subunit B-domain-containing protein. (758 aa)
A0A443HHT9Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (775 aa)
A0A443HI28P-loop containing nucleoside triphosphate hydrolase protein. (406 aa)
A0A443HIK2Replication factor-a protein. (274 aa)
A0A443HJ32Glycosyl transferase family protein. (324 aa)
A0A443HJ63Subunit of heteropentameric replication factor. (396 aa)
A0A443HJP4Uncharacterized protein. (415 aa)
A0A443HLT9DNA repair and recombination protein RAD54. (1774 aa)
A0A443HLY2Putative DNA repair protein RAD1. (973 aa)
A0A443HM03Putative DNA replication factor C subunit Rfc4. (808 aa)
A0A443HMC8Meiotic recombination protein DMC1; Belongs to the RecA family. (614 aa)
A0A443HMQ5Putative DNA damage inducible protein. (607 aa)
A0A443HN79DNA repair protein RAD50, ABC-type ATPase/SMC superfamily. (1312 aa)
A0A443HN84Putative DNA repair protein Rad1. (492 aa)
A0A443HNH3Chromosome transmission fidelity protein 8. (167 aa)
A0A443HNI1Putative DNA polymerase iota. (620 aa)
A0A443HNU5Exonuclease. (568 aa)
A0A443HNZ0Putative DNA repair protein Mus81. (603 aa)
A0A443HP83Putative rad57 protein. (535 aa)
A0A443HPF7Histone-fold-containing protein. (294 aa)
A0A443HPI3DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
A0A443HPV3Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (605 aa)
A0A443HPZ4Putative mitotic spindle checkpoint protein. (288 aa)
A0A443HQ10Uncharacterized protein. (407 aa)
A0A443HQQ1Checkpoint protein; Belongs to the HUS1 family. (356 aa)
A0A443HR83Putative phosphatidylinositol 3 and 4-kinase; Belongs to the PI3/PI4-kinase family. (2475 aa)
A0A443HRV3DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1167 aa)
A0A443HRY0RecQ family helicase MusN. (1562 aa)
A0A443HS20DNA polymerase subunit Cdc27. (460 aa)
A0A443HSG1Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2901 aa)
A0A443HSS5DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (501 aa)
A0A443HSW2ATP-dependent DNA helicase MPH1. (1123 aa)
A0A443HT57Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (826 aa)
A0A443HTD0Chromosome transmission fidelity protein 18. (1050 aa)
A0A443HTE7DNA repair protein endonuclease SAE2/CtIP C-terminus-domain-containing protein. (674 aa)
A0A443HUP9DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (444 aa)
A0A443HUW1DNA polymerase family B-domain-containing protein. (2008 aa)
A0A443HW48Putative dsDNA-dependent ATPase. (965 aa)
A0A443HW53AA_TRNA_LIGASE_II domain-containing protein. (563 aa)
A0A443HWS8Uncharacterized protein. (768 aa)
A0A443HWZ2DNA primase; Belongs to the eukaryotic-type primase small subunit family. (527 aa)
A0A443HZN8Mating-type switching protein Swi10. (327 aa)
A0A443HZY2RAD52 DNA repair protein. (601 aa)
A0A443I017ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (599 aa)
A0A443I0N3DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2235 aa)
A0A443I0U3Rad51 family DNA repair protein. (459 aa)
A0A443I0Z4DNA polymerase. (1106 aa)
A0A443I187DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (655 aa)
A0A443I1S7BRCT domain-containing protein. (1558 aa)
A0A443I230Putative DNA replication factor C subunit Rfc5. (345 aa)
A0A443I254Replication factor C subunit 1. (1068 aa)
A0A443I2I4DNA polymerase alpha/epsilon subunit B-domain-containing protein. (556 aa)
A0A443I3H13'-5' exonuclease domain-containing protein. (966 aa)
A0A443I4K7DNA polymerase. (1706 aa)
A0A443I4T4AAA domain-containing protein. (763 aa)
A0A443I512DUF1767 domain-containing protein. (269 aa)
A0A443I5V4Uncharacterized protein. (521 aa)
A0A443I5W3DNA replication factor Dna2. (92 aa)
A0A443I655Rad17 cell cycle checkpoint protein-domain-containing protein. (828 aa)
A0A443I7T0DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (628 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (400 aa)
A0A443I8J7Putative SNF2 family helicase/ATPase. (1844 aa)
Your Current Organism:
Byssochlamys spectabilis
NCBI taxonomy Id: 264951
Other names: ATCC 90900, B. spectabilis, Byssochlamys spectabilis (Udagawa & Shoji Suzuki) Houbraken & Samson 2008, CBS 101075, FRR 5219, JCM 12815, Pacilomyces variotii, Paecilomyces spectabilis, Paecilomyces variotii, Paecilomyces variotti, Paecilomyces vatiotii, Talaromyces spectabilis
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.