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A0A443HHP4 A0A443HHP4 A0A443HJ57 A0A443HJ57 A0A443HJB3 A0A443HJB3 VdtC VdtC A0A443HJZ7 A0A443HJZ7 A0A443HK33 A0A443HK33 A0A443HK35 A0A443HK35 A0A443HKK4 A0A443HKK4 A0A443HKU0 A0A443HKU0 A0A443HKY2 A0A443HKY2 A0A443HKZ7 A0A443HKZ7 A0A443HLP8 A0A443HLP8 A0A443HM07 A0A443HM07 COQ3 COQ3 A0A443HQ42 A0A443HQ42 A0A443HQE8 A0A443HQE8 A0A443HQE9 A0A443HQE9 A0A443HQX4 A0A443HQX4 A0A443HRA8 A0A443HRA8 A0A443HRB8 A0A443HRB8 COQ5 COQ5 A0A443HSP9 A0A443HSP9 A0A443HTH9 A0A443HTH9 A0A443HU43 A0A443HU43 A0A443HUX1 A0A443HUX1 A0A443HVC2 A0A443HVC2 EFM7 EFM7 A0A443HX58 A0A443HX58 A0A443HXH9 A0A443HXH9 A0A443HXK1 A0A443HXK1 A0A443HXR2 A0A443HXR2 A0A443HY74 A0A443HY74 A0A443HYE4 A0A443HYE4 EFM6 EFM6 A0A443I0B7 A0A443I0B7 A0A443I0S1 A0A443I0S1 A0A443I0Z1 A0A443I0Z1 EFM4 EFM4 A0A443I1F8 A0A443I1F8 A0A443I1L3 A0A443I1L3 A0A443I1M7 A0A443I1M7 A0A443I1P4 A0A443I1P4 A0A443I1R5 A0A443I1R5 A0A443I1W2 A0A443I1W2 A0A443I3S9 A0A443I3S9 A0A443I413 A0A443I413 A0A443I4F6 A0A443I4F6 A0A443I4F8 A0A443I4F8 TRM5 TRM5 A0A443I5E2 A0A443I5E2 A0A443I5K0 A0A443I5K0 A0A443I618 A0A443I618 TRM8 TRM8 A0A443I6C8 A0A443I6C8 A0A443I6G0 A0A443I6G0 A0A443I6P3 A0A443I6P3 A0A443I729 A0A443I729 SPB1 SPB1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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A0A443HHP4Cell division protein ftsj. (321 aa)
A0A443HJ57Putative O-methyltransferase. (418 aa)
A0A443HJB3Putative nucleolar RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (719 aa)
VdtCO-methyltransferase VdtC; O-methyltransferase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity. The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin. The product of VdtA is then O-methylated on C7 by the O- methyltransferase VdtC. The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosyn [...] (433 aa)
A0A443HJZ7Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (893 aa)
A0A443HK33Putative diphthine synthase. (285 aa)
A0A443HK35Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (408 aa)
A0A443HKK4Putative NOL1/NOP2/sun domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (559 aa)
A0A443HKU0S-adenosyl-L-methionine-dependent methyltransferase. (386 aa)
A0A443HKY2Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (576 aa)
A0A443HKZ7Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (957 aa)
A0A443HLP8S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1166 aa)
A0A443HM07Ribosomal lysine N-methyltransferase 4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that monomethylates 60S ribosomal protein L42. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (486 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (337 aa)
A0A443HQ42Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. (982 aa)
A0A443HQE8C-5 cytosine methyltransferase DmtA; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (666 aa)
A0A443HQE9Uncharacterized protein. (393 aa)
A0A443HQX4Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (239 aa)
A0A443HRA8O-methyltransferase. (384 aa)
A0A443HRB8Putative O-methyltransferase. (397 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (316 aa)
A0A443HSP9Putative C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (2097 aa)
A0A443HTH9O-methyltransferase. (400 aa)
A0A443HU43S-adenosyl-L-methionine-dependent methyltransferase. (403 aa)
A0A443HUX1Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (524 aa)
A0A443HVC2Histone-lysine n-methyltransferase, suv9. (482 aa)
EFM7Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family. (264 aa)
A0A443HX58Protein arginine methyltransferase RmtB; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (550 aa)
A0A443HXH9Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (290 aa)
A0A443HXK1Histone-lysine N-methyltransferase set9. (639 aa)
A0A443HXR2O-methyltransferase-domain-containing protein. (424 aa)
A0A443HY74Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (377 aa)
A0A443HYE4Putative Sterigmatocystin 8-O-methyltransferase. (395 aa)
EFM6Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily. (250 aa)
A0A443I0B7rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (390 aa)
A0A443I0S1S-adenosyl-L-methionine-dependent methyltransferase. (439 aa)
A0A443I0Z1Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (421 aa)
EFM4Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (389 aa)
A0A443I1F8O-methyltransferase-domain-containing protein. (423 aa)
A0A443I1L3S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (551 aa)
A0A443I1M7tRNA wybutosine-synthesizing protein 2; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. (441 aa)
A0A443I1P4Protein methyltransferase RmtC; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (878 aa)
A0A443I1R5DUF858 domain-containing protein. (234 aa)
A0A443I1W22-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (447 aa)
A0A443I3S92-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (571 aa)
A0A443I413Protein-L-isoaspartate O-methyltransferase. (241 aa)
A0A443I4F6Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (424 aa)
A0A443I4F8Putative histone-lysine N-methyltransferase. (833 aa)
TRM5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (478 aa)
A0A443I5E2S-adenosyl-L-methionine-dependent methyltransferase. (448 aa)
A0A443I5K0S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (316 aa)
A0A443I618Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1256 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (326 aa)
A0A443I6C8Putative N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (1056 aa)
A0A443I6G025S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs to the BMT2 family. (296 aa)
A0A443I6P3Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (201 aa)
A0A443I729Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (500 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (814 aa)
Your Current Organism:
Byssochlamys spectabilis
NCBI taxonomy Id: 264951
Other names: ATCC 90900, B. spectabilis, Byssochlamys spectabilis (Udagawa & Shoji Suzuki) Houbraken & Samson 2008, CBS 101075, FRR 5219, JCM 12815, Pacilomyces variotii, Paecilomyces spectabilis, Paecilomyces variotii, Paecilomyces variotti, Paecilomyces vatiotii, Talaromyces spectabilis
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