node1 | node2 | node1 annotation | node2 annotation | score |
A0A443HHD3 | A0A443HMX4 | Serine hydrolase-domain-containing protein. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.784 |
A0A443HHD3 | A0A443HUV7 | Serine hydrolase-domain-containing protein. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.576 |
A0A443HHD3 | A0A443HZZ3 | Serine hydrolase-domain-containing protein. | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.784 |
A0A443HHD3 | A0A443I0K8 | Serine hydrolase-domain-containing protein. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.821 |
A0A443HHD3 | A0A443I4C6 | Serine hydrolase-domain-containing protein. | Dihydrofolate reductase. | 0.752 |
A0A443HHD3 | A0A443I5A6 | Serine hydrolase-domain-containing protein. | Putative C1 tetrahydrofolate synthase. | 0.859 |
A0A443HHD3 | A0A443I6Y6 | Serine hydrolase-domain-containing protein. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.821 |
A0A443HHD3 | A0A443I7Q0 | Serine hydrolase-domain-containing protein. | Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase. | 0.798 |
A0A443HHD3 | A0A443I829 | Serine hydrolase-domain-containing protein. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.576 |
A0A443HI10 | A0A443HMX4 | 5-formyltetrahydrofolate cyclo-ligase. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.413 |
A0A443HI10 | A0A443I0K8 | 5-formyltetrahydrofolate cyclo-ligase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.840 |
A0A443HI10 | A0A443I5A6 | 5-formyltetrahydrofolate cyclo-ligase. | Putative C1 tetrahydrofolate synthase. | 0.954 |
A0A443HI10 | A0A443I6Y6 | 5-formyltetrahydrofolate cyclo-ligase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.840 |
A0A443HI10 | A0A443I7Q0 | 5-formyltetrahydrofolate cyclo-ligase. | Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase. | 0.949 |
A0A443HLV5 | A0A443I5A6 | Putative mitochondrial folate carrier protein Flx1; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Putative C1 tetrahydrofolate synthase. | 0.443 |
A0A443HMX4 | A0A443HHD3 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydrolase-domain-containing protein. | 0.784 |
A0A443HMX4 | A0A443HI10 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 5-formyltetrahydrofolate cyclo-ligase. | 0.413 |
A0A443HMX4 | A0A443HUV7 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.543 |
A0A443HMX4 | A0A443HXP4 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Putative dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.863 |
A0A443HMX4 | A0A443HZZ3 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.893 |