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| | Mfla_0034 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (256 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: tbd:Tbd_0229 argininosuccinate lyase; COGs: COG0165 Argininosuccinate lyase category=E. (468 aa) |
| | ubiC | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (178 aa) |
| | Mfla_0061 | TIGRFAM: citrate synthase I; PRIAM: Citrate (Si)-synthase; PFAM: Citrate synthase; KEGG: tbd:Tbd_1187 citrate synthase I; COGs: COG0372 Citrate synthase category=C; Belongs to the citrate synthase family. (430 aa) |
| | Mfla_0101 | Aminotransferase. (331 aa) |
| | cobD | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (317 aa) |
| | ilvA | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (503 aa) |
| | moaC | GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (161 aa) |
| | Mfla_0250 | 3-hexulose-6-phosphate synthase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mca:MCA3049 hexulose-6-phosphate synthase; COGs: COG0269 3-hexulose-6-phosphate synthase and related proteins category=G. (228 aa) |
| | hisB | PRIAM: Imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: tbd:Tbd_1711 imidazoleglycerol-phosphate dehydratase; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase category=E. (198 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (214 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | Mfla_0314 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (411 aa) |
| | ilvD | TIGRFAM: dihydroxy-acid dehydratase; PRIAM: Dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: cvi:CV1277 dihydroxy-acid dehydratase; COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase category=G; Belongs to the IlvD/Edd family. (616 aa) |
| | Mfla_0421 | Lytic transglycosylase, catalytic. (190 aa) |
| | Mfla_0525 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (360 aa) |
| | Mfla_0532 | Conserved hypothetical protein. (294 aa) |
| | moaA | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | Mfla_0591 | PRIAM: Deoxyribodipyrimidine photolyase; PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein; KEGG: cvi:CV3481 deoxyribodipyrimidine photo-lyase; COGs: COG0415 Deoxyribodipyrimidine photolyase category=L. (481 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa) |
| | cysG | Precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (493 aa) |
| | mutM | Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (279 aa) |
| | Mfla_0739 | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (132 aa) |
| | Mfla_0740 | Phosphate acetyltransferase. (318 aa) |
| | edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (624 aa) |
| | Mfla_0760 | TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PRIAM: 2-dehydro-3-deoxyphosphogluconate aldolase; PFAM: KDPG and KHG aldolase; KEGG: cvi:CV0143 2-dehydro-3-deoxy-phosphogluconate aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase category=G. (209 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (344 aa) |
| | Mfla_0800 | Carbonic anhydrase. (221 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (219 aa) |
| | Mfla_0893 | Fructose-6-phosphate phosphoketolase. (791 aa) |
| | Mfla_0905 | TIGRFAM: threonine synthase; PRIAM: Threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: dar:Daro_2382 threonine synthase; COGs: COG0498 Threonine synthase category=E. (475 aa) |
| | Mfla_0915 | PRIAM: Lysine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: dar:Daro_0578 Orn/Lys/Arg decarboxylase, major region:Orn/Lys/Arg decarboxylase, C-terminal; COGs: COG1982 Arginine/lysine/ornithine decarboxylases category=E. (746 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (232 aa) |
| | Mfla_0987 | TIGRFAM: dihydrodipicolinate synthase; PRIAM: Dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; KEGG: neu:NE2403 dihydrodipicolinate synthase; COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase category=M. (290 aa) |
| | Mfla_0995 | Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: bbr:BB3785 endonuclease III; COGs: COG0177 EndoIII-related endonuclease category=L. (219 aa) |
| | Mfla_1037 | Fructose-6-phosphate phosphoketolase. (791 aa) |
| | Mfla_1049 | TIGRFAM: threonine synthase; PRIAM: Threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: dar:Daro_2382 threonine synthase; COGs: COG0498 Threonine synthase category=E. (475 aa) |
| | Mfla_1059 | PRIAM: Lysine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: dar:Daro_0578 Orn/Lys/Arg decarboxylase, major region:Orn/Lys/Arg decarboxylase, C-terminal; COGs: COG1982 Arginine/lysine/ornithine decarboxylases category=E. (746 aa) |
| | Mfla_1067 | TIGRFAM: orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: cvi:CV3042 orotidine 5'-phosphate decarboxylase; COGs: COG0284 Orotidine-5'-phosphate decarboxylase category=F. (232 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa) |
| | mltF | Lytic transglycosylase, catalytic; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (472 aa) |
| | gmd | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (346 aa) |
| | Mfla_1322 | Pseudouridine synthase, RluD; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (326 aa) |
| | Mfla_1477 | 6-pyruvoyl tetrahydrobiopterin synthase. (146 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (334 aa) |
| | Mfla_1502 | Aminodeoxychorismate lyase apoprotein. (271 aa) |
| | Mfla_1512 | Oxaloacetate decarboxylase alpha subunit. (617 aa) |
| | fabZ | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (153 aa) |
| | Mfla_1545 | Conserved hypothetical protein. (229 aa) |
| | Mfla_1566 | Class II aldolase/adducin-like protein. (242 aa) |
| | Mfla_1571 | Adenylate/guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (426 aa) |
| | Mfla_1579 | PFAM: protein of unknown function DUF556; KEGG: noc:Noc_0020 hypothetical protein; COGs: COG1891 Uncharacterized protein conserved in archaea category=S. (236 aa) |
| | Mfla_1646 | PFAM: transcriptional coactivator/pterin dehydratase; KEGG: aae:aq_049 pterin-4a-carbinolamine dehydratase; COGs: COG2154 Pterin-4a-carbinolamine dehydratase category=H. (124 aa) |
| | Mfla_1648 | Aminodeoxychorismate synthase, subunit I. (460 aa) |
| | Mfla_1652 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. (178 aa) |
| | Mfla_1654 | 3-hexulose-6-phosphate synthase. (209 aa) |
| | Mfla_1686 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: cvi:CV2355 chorismate mutase/prephenate dehydratase; COGs: COG0077 Prephenate dehydratase category=E. (355 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (392 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (400 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (214 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa) |
| | Mfla_1817 | Aconitase; PRIAM: Aconitate hydratase; PFAM: aconitate hydratase domain protein; aconitate hydratase 2; KEGG: noc:Noc_2103 aconitate hydratase; COGs: COG1049 Aconitase B category=C; Belongs to the aconitase/IPM isomerase family. (855 aa) |
| | Mfla_1819 | TIGRFAM: adenylosuccinate lyase; PRIAM: Adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tbd:Tbd_0518 adenylosuccinate lyase; COGs: COG0015 Adenylosuccinate lyase category=F; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa) |
| | Mfla_1861 | TIGRFAM: cysteine synthases; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: dar:Daro_1287 cysteine synthase K/M:cysteine synthase B; COGs: COG0031 Cysteine synthase category=E; Belongs to the cysteine synthase/cystathionine beta- synthase family. (295 aa) |
| | sucD | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa) |
| | fabA | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | nnrD | YjeF-related protein-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repai [...] (487 aa) |
| | Mfla_1918 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (542 aa) |
| | Mfla_2008 | TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: pae:PA5161 dTDP-D-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase category=M; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (366 aa) |
| | Mfla_2033 | Pyridoxal-dependent decarboxylase. (490 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (361 aa) |
| | Mfla_2119 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: tbd:Tbd_1991 acetolactate synthase, large subunit; COGs: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase] category=H. (568 aa) |
| | Mfla_2120 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: tbd:Tbd_1990 acetolactate synthase, small subunit; COGs: COG0440 Acetolactate synthase small (regulatory) subunit category=E. (163 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (280 aa) |
| | Mfla_2129 | Adenylate/guanylate cyclase. (741 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | cynS | Cyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (147 aa) |
| | Mfla_2190 | Protein of unknown function UPF0047. (139 aa) |
| | purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | Mfla_2243 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (349 aa) |
| | moaA-2 | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (343 aa) |
| | Mfla_2328 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (152 aa) |
| | queE | Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (212 aa) |
| | Mfla_2363 | Protein of unknown function UPF0047. (139 aa) |
| | Mfla_2364 | KEGG: rba:RB9338 conserved hypothetical protein-putative formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. (182 aa) |
| | Mfla_2410 | Lytic transglycosylase, catalytic. (208 aa) |
| | cobD-2 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (304 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (445 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa) |
| | Mfla_2464 | Porphobilinogen synthase; Belongs to the ALAD family. (335 aa) |
| | trpC | PRIAM: Indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; KEGG: dar:Daro_3475 indole-3-glycerol phosphate synthase; COGs: COG0134 Indole-3-glycerol phosphate synthase category=E; Belongs to the TrpC family. (271 aa) |
| | Mfla_2468 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tbd:Tbd_2224 glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthases component II category=H. (188 aa) |
| | trpE | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (494 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (310 aa) |
| | Mfla_2524 | KEGG: rba:RB9338 conserved hypothetical protein-putative formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. (183 aa) |
| | thiC | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (628 aa) |
| | Mfla_2543 | KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S. (178 aa) |
| | Mfla_2623 | VanZ like protein. (136 aa) |
| | Mfla_2635 | MltA. (421 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa) |
