STRINGSTRING
Rxyl_0371 Rxyl_0371 Rxyl_0372 Rxyl_0372 Rxyl_0375 Rxyl_0375 Rxyl_0425 Rxyl_0425 acsA acsA Rxyl_1288 Rxyl_1288 Rxyl_1289 Rxyl_1289 Rxyl_1291 Rxyl_1291 Rxyl_1569 Rxyl_1569 Rxyl_1582 Rxyl_1582 Rxyl_1689 Rxyl_1689 Rxyl_1704 Rxyl_1704 Rxyl_1711 Rxyl_1711 Rxyl_1716 Rxyl_1716 Rxyl_1736 Rxyl_1736 Rxyl_1737 Rxyl_1737 Rxyl_1738 Rxyl_1738 Rxyl_1761 Rxyl_1761 Rxyl_1762 Rxyl_1762 Rxyl_1841 Rxyl_1841 Rxyl_1842 Rxyl_1842 Rxyl_2050 Rxyl_2050 Rxyl_2051 Rxyl_2051 Rxyl_2052 Rxyl_2052 Rxyl_2053 Rxyl_2053 Rxyl_2054 Rxyl_2054 Rxyl_2056 Rxyl_2056 Rxyl_2057 Rxyl_2057 Rxyl_2060 Rxyl_2060 Rxyl_2061 Rxyl_2061 Rxyl_2273 Rxyl_2273 Rxyl_2274 Rxyl_2274 Rxyl_2275 Rxyl_2275 Rxyl_2276 Rxyl_2276 Rxyl_2277 Rxyl_2277 Rxyl_2278 Rxyl_2278 Rxyl_2279 Rxyl_2279 Rxyl_2280 Rxyl_2280 Rxyl_2289 Rxyl_2289 Rxyl_2336 Rxyl_2336 Rxyl_2341 Rxyl_2341 Rxyl_2342 Rxyl_2342 Rxyl_2343 Rxyl_2343 Rxyl_2344 Rxyl_2344 Rxyl_2345 Rxyl_2345 Rxyl_2360 Rxyl_2360 Rxyl_2368 Rxyl_2368 Rxyl_2380 Rxyl_2380 Rxyl_2382 Rxyl_2382 Rxyl_2383 Rxyl_2383 Rxyl_2385 Rxyl_2385 Rxyl_2386 Rxyl_2386 Rxyl_2387 Rxyl_2387 Rxyl_2389 Rxyl_2389 Rxyl_2393 Rxyl_2393 Rxyl_2452 Rxyl_2452 Rxyl_2453 Rxyl_2453 Rxyl_2454 Rxyl_2454 Rxyl_2455 Rxyl_2455 Rxyl_2457 Rxyl_2457 Rxyl_2458 Rxyl_2458 Rxyl_2482 Rxyl_2482 Rxyl_2530 Rxyl_2530 Rxyl_2531 Rxyl_2531 Rxyl_2735 Rxyl_2735 Rxyl_2903 Rxyl_2903 Rxyl_3046 Rxyl_3046 Rxyl_3175 Rxyl_3175
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rxyl_0371PFAM: AMP-dependent synthetase and ligase; KEGG: chy:CHY_2411 long-chain-fatty-acid--CoA ligase. (544 aa)
Rxyl_0372PFAM: Enoyl-CoA hydratase/isomerase; KEGG: afu:AF0435 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
Rxyl_0375PFAM: acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like; KEGG: cef:CE0723 putative glutaryl-CoA dehydrogenase precursor. (385 aa)
Rxyl_0425PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: sma:SAV1542 putative dehydrogenase. (294 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa)
Rxyl_1288PFAM: beta-lactamase-like; KEGG: reu:Reut_A0157 beta-lactamase-like. (329 aa)
Rxyl_1289PFAM: MaoC-like dehydratase; KEGG: pfl:PFL_2678 MaoC family protein. (149 aa)
Rxyl_1291PFAM: nitroreductase; KEGG: bld:BLi00873 hypothetical protein. (191 aa)
Rxyl_1569TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: tfu:Tfu_2245 acetoacetyl-CoA synthase. (664 aa)
Rxyl_1582Acetyl-CoA C-acetyltransferase; PFAM: Thiolase; KEGG: tth:TTC0623 beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
Rxyl_1689TIGRFAM: Propionate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RSc1518 PrpE protein ligase (putative propionyl-CoA synthetase). (636 aa)
Rxyl_1704PFAM: AMP-dependent synthetase and ligase; KEGG: bpm:BURPS1710b_1709 acetyl-coenzyme A synthetase. (576 aa)
Rxyl_1711PFAM: AMP-dependent synthetase and ligase; KEGG: dra:DR0460 acetyl-CoA synthase. (653 aa)
Rxyl_1716TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: bha:BH2312 methylmalonate-semialdehyde dehydrogenase. (505 aa)
Rxyl_1736PFAM: NAD-dependent epimerase/dehydratase short-chain dehydrogenase/reductase SDR; KEGG: pae:PA2554 3-hydroxyacyl-CoA dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
Rxyl_1737PFAM: Thiolase 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; KEGG: jan:Jann_0668 thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
Rxyl_1738PFAM: AMP-dependent synthetase and ligase; KEGG: gka:GK1030 long-chain fatty-acid-CoA ligase. (549 aa)
Rxyl_1761PFAM: 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: sth:STH214 3-hydroxyacyl-CoA dehydrogenase. (377 aa)
Rxyl_1762PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bld:BLi02140 similar to 3-hydroxbutyryl-CoA dehydratase; RBL01969. (267 aa)
Rxyl_1841PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ctc:CTC02427 putative crotonase. (150 aa)
Rxyl_1842Acetyl-CoA C-acetyltransferase; PFAM: Thiolase 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; KEGG: mag:amb2989 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (360 aa)
Rxyl_2050PFAM: aldo/keto reductase; KEGG: cch:Cag_1232 putative aldo/keto reductase. (318 aa)
Rxyl_2051Alpha-mannosidase; PFAM: glycoside hydrolase, family 38 glycosyl hydrolases 38-like; KEGG: ret:RHE_PF00487 putative alpha-mannosidase protein. (1063 aa)
Rxyl_2052PFAM: AMP-dependent synthetase and ligase; KEGG: chy:CHY_1629 AMP-binding enzyme family protein. (523 aa)
Rxyl_2053PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: sma:SAV5929 hypothetical protein. (227 aa)
Rxyl_2054PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mag:amb0852 enoyl-CoA hydratase/carnithine racemase. (264 aa)
Rxyl_2056PFAM: Thiolase; KEGG: sth:STH3011 acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Rxyl_2057PFAM: Enoyl-CoA hydratase/isomerase 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: sru:SRU_1210 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family. (790 aa)
Rxyl_2060PFAM: AMP-dependent synthetase and ligase; KEGG: sru:SRU_2380 AMP-binding enzyme, putative. (592 aa)
Rxyl_2061PFAM: acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like; KEGG: cef:CE0723 putative glutaryl-CoA dehydrogenase precursor. (404 aa)
Rxyl_2273Hypothetical protein. (318 aa)
Rxyl_2274PFAM: NADH:flavin oxidoreductase/NADH oxidase monooxygenase, FAD-binding; KEGG: rso:RS02007 hypothetical protein. (771 aa)
Rxyl_2275PFAM: NAD-dependent epimerase/dehydratase short-chain dehydrogenase/reductase SDR; KEGG: reu:Reut_A2183 NAD-dependent epimerase/dehydratase:short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa)
Rxyl_2276Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR; KEGG: reu:Reut_A2992 regulatory protein, MarR. (158 aa)
Rxyl_2277PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rso:RS02010 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (272 aa)
Rxyl_2278PFAM: acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like; KEGG: rso:RS02011 probable acyl-CoA dehydrogenase oxidoreductase protein. (390 aa)
Rxyl_2279PFAM: AMP-dependent synthetase and ligase; KEGG: nfa:nfa12430 putative acyl-CoA synthetase. (543 aa)
Rxyl_2280PFAM: Endoribonuclease L-PSP; KEGG: mlo:mll5429 hypothetical protein. (132 aa)
Rxyl_2289PFAM: lipase, class 2; KEGG: sco:SCO1735 secreted lipase. (286 aa)
Rxyl_2336PFAM: 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: bha:BH1995 3-hydroxybutyryl-CoA dehydrogenase. (287 aa)
Rxyl_2341PFAM: Enoyl-CoA hydratase/isomerase; KEGG: gka:GK2038 enoyl-CoA hydratase subunit II (phenylacetic acid catabolism); Belongs to the enoyl-CoA hydratase/isomerase family. (266 aa)
Rxyl_2342TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: gka:GK1485 acetoacetyl-CoA synthetase. (660 aa)
Rxyl_2343TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: tfu:Tfu_0081 3-hydroxybutyrate dehydrogenase. (262 aa)
Rxyl_2344PFAM: General substrate transporter major facilitator superfamily MFS_1; KEGG: bja:bll0889 putative transport protein. (461 aa)
Rxyl_2345LigA; KEGG: ade:Adeh_0244 LigA. (490 aa)
Rxyl_2360PFAM: Thiolase; KEGG: tth:TTC0330 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
Rxyl_2368PFAM: Enoyl-CoA hydratase/isomerase; KEGG: tte:TTE0544 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
Rxyl_2380PFAM: aldehyde dehydrogenase; KEGG: reu:Reut_A2614 aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (487 aa)
Rxyl_2382PFAM: AMP-dependent synthetase and ligase; KEGG: sma:SAV6612 putative acyl-CoA synthetase, long chain-fatty acid:CoA ligase. (561 aa)
Rxyl_2383PFAM: peptidase S15 X-Pro dipeptidyl-peptidase-like; KEGG: cya:CYA_1044 X-Pro dipeptidyl-peptidase (S15 family). (571 aa)
Rxyl_2385TIGRFAM: Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit; PFAM: alpha/beta hydrolase fold PHB de-polymerase-like; KEGG: btk:BT9727_1208 poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit. (358 aa)
Rxyl_2386TIGRFAM: Poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold Poly-beta-hydroxybutyrate polymerase-like; KEGG: rru:Rru_A2413 poly(R)-hydroxyalkanoic acid synthase, class I. (614 aa)
Rxyl_2387PFAM: acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like; KEGG: afu:AF0991 glutaryl-CoA dehydrogenase (GcdH). (402 aa)
Rxyl_2389PFAM: Thiolase; KEGG: tte:TTE0549 Acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Rxyl_2393PFAM: NAD-dependent epimerase/dehydratase short-chain dehydrogenase/reductase SDR; KEGG: btk:BT9727_1207 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-CoA reductase). (247 aa)
Rxyl_2452PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ilo:IL1485 short chain dehydrogenase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
Rxyl_2453PFAM: Enoyl-CoA hydratase/isomerase 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: sru:SRU_1459 fatty oxidation complex, alpha subunit; Belongs to the enoyl-CoA hydratase/isomerase family. (702 aa)
Rxyl_2454PFAM: Thiolase; KEGG: sru:SRU_1460 fatty oxidation complex, beta subunit; Belongs to the thiolase-like superfamily. Thiolase family. (436 aa)
Rxyl_2455PFAM: acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like; KEGG: cef:CE0723 putative glutaryl-CoA dehydrogenase precursor. (398 aa)
Rxyl_2457PFAM: short-chain dehydrogenase/reductase SDR; KEGG: gga:421130 similar to Zgc:63829; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (291 aa)
Rxyl_2458PFAM: AMP-dependent synthetase and ligase; KEGG: plt:Plut_0972 long-chain fatty-acid-CoA ligase. (612 aa)
Rxyl_2482PFAM: acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like; KEGG: chy:CHY_1350 butyryl-CoA dehydrogenase. (395 aa)
Rxyl_2530PFAM: Thiolase; KEGG: gka:GK3397 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Rxyl_2531PFAM: AMP-dependent synthetase and ligase; KEGG: chy:CHY_0572 acetyl-coenzyme A synthetase family protein. (537 aa)
Rxyl_2735PFAM: acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like; KEGG: reu:Reut_B3542 acyl-CoA dehydrogenase, C-terminal:acyl-CoA dehydrogenase, central region:acyl-CoA dehydrogenase, N-terminal. (381 aa)
Rxyl_2903TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: tfu:Tfu_0690 bacterial 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (438 aa)
Rxyl_3046PFAM: short-chain dehydrogenase/reductase SDR; KEGG: gka:GK1683 short chain dehydrogenase. (252 aa)
Rxyl_3175Succinate-semialdehyde dehydrogenase (NAD(P)+); PFAM: aldehyde dehydrogenase; KEGG: ade:Adeh_3025 aldehyde dehydrogenase. (465 aa)
Your Current Organism:
Rubrobacter xylanophilus
NCBI taxonomy Id: 266117
Other names: R. xylanophilus DSM 9941, Rubrobacter xylanophilus DSM 9941, Rubrobacter xylanophilus str. DSM 9941, Rubrobacter xylanophilus strain DSM 9941
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