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| | Rxyl_0072 | PFAM: peptidase M20 peptidase dimerisation; KEGG: ade:Adeh_3828 peptidase M20. (354 aa) |
| | Rxyl_0073 | KEGG: ade:Adeh_3829 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (269 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (416 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (262 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (260 aa) |
| | Rxyl_0098 | KEGG: deh:cbdb_A1731 aspartate kinase, monofunctional class; TIGRFAM: aspartate kinase aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase amino acid-binding ACT; Belongs to the aspartokinase family. (422 aa) |
| | Rxyl_0180 | Peptidase M20D, amidohydrolase; KEGG: rsp:RSP_2910 predicted metal-dependent amidase/aminoacylase/carboxypeptidase; TIGRFAM: Peptidase M20D, amidohydrolase; PFAM: peptidase M20 peptidase dimerisation. (393 aa) |
| | Rxyl_0221 | Amidase, hydantoinase/carbamoylase; KEGG: sai:Saci_2132 N-carbamoyl-L-amino acid amidohydrolase; TIGRFAM: Amidase, hydantoinase/carbamoylase; PFAM: peptidase M20. (417 aa) |
| | leuC1 | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (195 aa) |
| | trpB | Tryptophan synthase, beta chain-like protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (450 aa) |
| | Rxyl_0341 | PFAM: glutamine amidotransferase, class-II glutamate synthase, alpha subunit-like ferredoxin-dependent glutamate synthase glutamate synthase; KEGG: mca:MCA2039 glutamate synthase, large subunit. (1489 aa) |
| | Rxyl_0342 | TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mpa:MAP0173 glutamate synthase (NADPH) small chain. (475 aa) |
| | Rxyl_0356 | Hypothetical protein. (233 aa) |
| | Rxyl_0455 | PFAM: peptidase M20 peptidase dimerisation; KEGG: tth:TTC0765 hypothetical protein. (459 aa) |
| | Rxyl_0463 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: noc:Noc_2604 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (327 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (474 aa) |
| | Rxyl_0582 | Amidase, hydantoinase/carbamoylase; KEGG: gka:GK3252 N-carbamoyl-L-amino acid amidohydrolase; TIGRFAM: Amidase, hydantoinase/carbamoylase; PFAM: peptidase M20. (405 aa) |
| | Rxyl_0650 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase, putative; PFAM: aminotransferase, class I and II; KEGG: det:DET0689 histidinol-phosphate aminotransferase, putative. (366 aa) |
| | Rxyl_0685 | KEGG: sco:SCO0913 hypothetical protein. (330 aa) |
| | Rxyl_0695 | PFAM: inositol monophosphatase; KEGG: cte:CT1430 myo-inositol-1(or 4)-monophosphatase. (259 aa) |
| | Rxyl_0725 | PFAM: amino acid-binding ACT Prephenate dehydrogenase; KEGG: dra:DR1122 prephenate dehydrogenase. (339 aa) |
| | hisC | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: chy:CHY_1929 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (351 aa) |
| | Rxyl_0743 | PFAM: UBA/THIF-type NAD/FAD binding fold Rhodanese-like MoeZ/MoeB; KEGG: gvi:gll3412 molybdopterin biosynthesis MoeB protein homolog. (392 aa) |
| | Rxyl_0744 | PFAM: thiamineS; KEGG: cyb:CYB_2074 ThiS domain protein. (91 aa) |
| | Rxyl_0746 | KEGG: cyb:CYB_2315 putative cysteine synthase B; TIGRFAM: cysteine synthases; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (305 aa) |
| | Rxyl_0761 | Aminodeoxychorismate synthase, subunit I; KEGG: mta:Moth_2108 para-aminobenzoate synthase component I; TIGRFAM: para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I and chorismate binding protein Anthranilate synthase component I-like. (480 aa) |
| | Rxyl_0763 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: noc:Noc_2604 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (321 aa) |
| | Rxyl_0804 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (365 aa) |
| | folD1 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | Rxyl_0835 | Dihydroxyacid dehydratase/phosphogluconate dehydratase-like protein; KEGG: lxx:Lxx13210 dihydroxy-acid dehydratase protein; Belongs to the IlvD/Edd family. (413 aa) |
| | Rxyl_0837 | KEGG: tfu:Tfu_0614 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (527 aa) |
| | Rxyl_0841 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: pto:PTO0186 methionine synthase. (385 aa) |
| | Rxyl_0842 | Cobalamin-independent synthase MetE-like protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (311 aa) |
| | Rxyl_0933 | PFAM: Methionine synthase, vitamin-B12 independent Cobalamin-independent synthase MetE-like; KEGG: rpb:RPB_1584 methionine synthase, vitamin-B12 independent. (369 aa) |
| | Rxyl_0944 | PFAM: thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate enzyme, central region thiamine pyrophosphate enzyme-like TPP binding region; KEGG: rpa:RPA1609 benzoylformate decarboxylase; Belongs to the TPP enzyme family. (527 aa) |
| | Rxyl_0960 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (353 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: fra:Francci3_3168 argininosuccinate lyase. (505 aa) |
| | Rxyl_1031 | PFAM: glutamine synthetase, catalytic region; KEGG: mta:Moth_1764 glutamine synthetase, type I. (444 aa) |
| | Rxyl_1036 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20 peptidase dimerisation; KEGG: mlo:mlr7167 acetylornitine deacetylase. (426 aa) |
| | Rxyl_1061 | Selenophosphate synthase; TIGRFAM: selenide, water dikinase; PFAM: AIR synthase related protein-like; KEGG: mta:Moth_1625 selenide, water dikinase. (291 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (380 aa) |
| | Rxyl_1090 | KEGG: mka:MK0109 aspartokinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. (425 aa) |
| | Rxyl_1091 | PFAM: homoserine dehydrogenase homoserine dehydrogenase, NAD-binding; KEGG: xac:XAC1820 homoserine dehydrogenase / aspartate kinase. (360 aa) |
| | Rxyl_1092 | TIGRFAM: Aspartate-semialdehyde dehydrogenase, USG-1 related; PFAM: Semialdehyde dehydrogenase, NAD - binding Semialdehyde dehydrogenase, dimerisation region; KEGG: bce:BC3799 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (327 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (413 aa) |
| | hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (216 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (418 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: gox:GOX0479 imidazoleglycerol-phosphate dehydratase. (194 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (205 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis; KEGG: mta:Moth_2032 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (243 aa) |
| | Rxyl_1125 | KEGG: dde:Dde_0104 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region glutamine synthetase, beta-Grasp. (443 aa) |
| | Rxyl_1183 | KEGG: sth:STH2344 tartrate dehydrogenase; TIGRFAM: Tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (349 aa) |
| | Rxyl_1297 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mta:Moth_0993 isocitrate dehydrogenase (NAD+). (336 aa) |
| | ilvD | KEGG: tth:TTC0871 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (566 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (447 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (352 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (168 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (389 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase-like, ATP-grasp protein of unknown function DUF201 Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain, oligomerisation Carbamoyl-phosphate synthetase large chain-like MGS-like; KEGG: afu:AF1274 carbamoyl-phosphate synthase large chain. (1054 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I Carbamoyl-phosphate synthase, small chain; KEGG: plt:Plut_0156 carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (369 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (262 aa) |
| | Rxyl_1542 | PFAM: thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate enzyme, central region thiamine pyrophosphate enzyme-like TPP binding region; KEGG: bpm:BURPS1710b_1048 benzoylformate decarboxylase; Belongs to the TPP enzyme family. (542 aa) |
| | folD2 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (320 aa) |
| | Rxyl_1586 | PFAM: Methionine synthase, vitamin-B12 independent Cobalamin-independent synthase MetE-like; KEGG: rpb:RPB_1584 methionine synthase, vitamin-B12 independent. (371 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (153 aa) |
| | Rxyl_1635 | PFAM: peptidase M20 peptidase dimerisation; KEGG: bcl:ABC3512 succinyl-diaminopimelate desuccinylase. (400 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (434 aa) |
| | Rxyl_1692 | TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase-like; KEGG: pab:PAB0892 3-isopropylmalate dehydratase small subunit; Belongs to the LeuD family. (167 aa) |
| | leuC2 | Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (424 aa) |
| | Rxyl_1718 | PFAM: thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate enzyme, central region thiamine pyrophosphate enzyme-like TPP binding region; KEGG: sma:SAV7147 putative acetolactate synthase. (626 aa) |
| | Rxyl_1854 | Amidase, hydantoinase/carbamoylase; KEGG: gka:GK3252 N-carbamoyl-L-amino acid amidohydrolase; TIGRFAM: Amidase, hydantoinase/carbamoylase; PFAM: peptidase M20 peptidase dimerisation. (425 aa) |
| | Rxyl_2072 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 3-isopropylmalate dehydrogenase. (358 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa) |
| | trpB-2 | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: gsu:GSU2378 N-(5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (206 aa) |
| | Rxyl_2094 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: dps:DP1622 probable indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (255 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (342 aa) |
| | trpE | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (509 aa) |
| | hisI | PFAM: phosphoribosyl-AMP cyclohydrolase phosphoribosyl-ATP pyrophosphohydrolase; KEGG: bha:BH3577 phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. (213 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (250 aa) |
| | Rxyl_2271 | PFAM: thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate enzyme, central region thiamine pyrophosphate enzyme-like TPP binding region; KEGG: mka:MK0531 acetolactate synthase large subunit. (547 aa) |
| | Rxyl_2307 | Inositol-1(or 4)-monophosphatase; PFAM: inositol monophosphatase; KEGG: gsu:GSU0942 inositol-1-monophosphatase. (274 aa) |
| | Rxyl_2316 | PFAM: bifunctional deaminase-reductase-like; KEGG: bce:BC3158 pyrimidine reductase. (179 aa) |
| | Rxyl_2475 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20 peptidase dimerisation; KEGG: mlo:mlr1185 succinyl-diaminopimelate desuccinylase. (420 aa) |
| | Rxyl_2477 | PFAM: thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate enzyme, central region thiamine pyrophosphate enzyme-like TPP binding region; KEGG: gka:GK0373 acetolactate synthaselarge subunit. (543 aa) |
| | Rxyl_2498 | PFAM: glutamine synthetase, catalytic region; KEGG: psp:PSPPH_2916 glutamine synthetase, type III. (446 aa) |
| | Rxyl_2499 | Glutamate synthase (NADPH) GltB1 subunit; PFAM: glutamine amidotransferase, class-II; KEGG: psb:Psyr_2274 glutamine amidotransferase, class-II. (305 aa) |
| | Rxyl_2500 | PFAM: glutamate synthase, alpha subunit-like; KEGG: pst:PSPTO2584 hypothetical protein. (225 aa) |
| | Rxyl_2501 | Glutamate synthase (NADPH) GltB2 subunit; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase ferredoxin-dependent glutamate synthase; KEGG: pub:SAR11_1315 glutamate synthase large subunit; Belongs to the glutamate synthase family. (460 aa) |
| | folD3 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (318 aa) |
| | Rxyl_2537 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: sth:STH832 cystathionine gamma-lyase. (410 aa) |
| | Rxyl_2718 | PFAM: thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate enzyme, central region thiamine pyrophosphate enzyme-like TPP binding region; KEGG: noc:Noc_0471 pyruvate decarboxylase; Belongs to the TPP enzyme family. (594 aa) |
| | Rxyl_2745 | Amidase, hydantoinase/carbamoylase; KEGG: ret:RHE_CH00350 probable N-carbamoyl-L-amino acid amidohydrolase protein; TIGRFAM: Amidase, hydantoinase/carbamoylase; PFAM: peptidase M20 peptidase dimerisation. (417 aa) |
| | Rxyl_2877 | PFAM: GCN5-related N-acetyltransferase; KEGG: ade:Adeh_1022 tyrosine phosphatase. (147 aa) |
| | argG | PFAM: argininosuccinate synthase; KEGG: syf:Synpcc7942_0009 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (409 aa) |
| | argR | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. (159 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (340 aa) |
| | argJ | Glutamate N-acetyltransferase / N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (407 aa) |
| | argB | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (253 aa) |
| | argD | KEGG: mta:Moth_2287 acetylornithine and succinylornithine aminotransferases; TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (397 aa) |
| | Rxyl_2889 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (317 aa) |
| | Rxyl_3023 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mlr7936 diaminopropionate ammonia-lyase. (396 aa) |
| | Rxyl_3123 | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (355 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa) |
| | Rxyl_3125 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate enzyme, central region thiamine pyrophosphate enzyme-like TPP binding region; KEGG: det:DET0833 acetolactate synthase, large subunit, biosynthetic type. (564 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa) |
| | ilvE | Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (318 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (510 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa) |
| | Rxyl_3131 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: pab:PAB0894 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (520 aa) |
| | Rxyl_3192 | Cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: noc:Noc_2604 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (323 aa) |
| | Rxyl_3196 | PFAM: glutamine synthetase, catalytic region; KEGG: sco:SCO1613 putative glutamine synthetase. (455 aa) |
