node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rxyl_0727 | Rxyl_1244 | Rxyl_0727 | Rxyl_1244 | PFAM: Chorismate mutase; KEGG: ttj:TTHA0388 phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase. | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.951 |
Rxyl_0727 | aroA | Rxyl_0727 | Rxyl_1441 | PFAM: Chorismate mutase; KEGG: ttj:TTHA0388 phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.711 |
Rxyl_0727 | aroC | Rxyl_0727 | Rxyl_1461 | PFAM: Chorismate mutase; KEGG: ttj:TTHA0388 phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.971 |
Rxyl_0727 | aroK | Rxyl_0727 | Rxyl_1460 | PFAM: Chorismate mutase; KEGG: ttj:TTHA0388 phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.460 |
Rxyl_0960 | Rxyl_1244 | Rxyl_0960 | Rxyl_1244 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.845 |
Rxyl_0960 | aroB | Rxyl_0960 | Rxyl_1459 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.960 |
Rxyl_0960 | aroK | Rxyl_0960 | Rxyl_1460 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.468 |
Rxyl_1244 | Rxyl_0727 | Rxyl_1244 | Rxyl_0727 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | PFAM: Chorismate mutase; KEGG: ttj:TTHA0388 phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase. | 0.951 |
Rxyl_1244 | Rxyl_0960 | Rxyl_1244 | Rxyl_0960 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.845 |
Rxyl_1244 | aroA | Rxyl_1244 | Rxyl_1441 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.940 |
Rxyl_1244 | aroB | Rxyl_1244 | Rxyl_1459 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.818 |
Rxyl_1244 | aroC | Rxyl_1244 | Rxyl_1461 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.991 |
Rxyl_1244 | aroE | Rxyl_1244 | Rxyl_1362 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.827 |
Rxyl_1244 | aroK | Rxyl_1244 | Rxyl_1460 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.867 |
Rxyl_1244 | aroQ | Rxyl_1244 | Rxyl_1588 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.739 |
aroA | Rxyl_0727 | Rxyl_1441 | Rxyl_0727 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | PFAM: Chorismate mutase; KEGG: ttj:TTHA0388 phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase. | 0.711 |
aroA | Rxyl_1244 | Rxyl_1441 | Rxyl_1244 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.940 |
aroA | aroB | Rxyl_1441 | Rxyl_1459 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.993 |
aroA | aroC | Rxyl_1441 | Rxyl_1461 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.994 |
aroA | aroE | Rxyl_1441 | Rxyl_1362 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.984 |