STRINGSTRING
Bxe_A2345 Bxe_A2345 Bxe_A0262 Bxe_A0262 pyrE pyrE Bxe_A0354 Bxe_A0354 hisG hisG hisH hisH hisF hisF trpD trpD ftsW ftsW murG murG Bxe_A0515 Bxe_A0515 mtgA mtgA Bxe_A0678 Bxe_A0678 Bxe_A0684 Bxe_A0684 Bxe_A0732 Bxe_A0732 Bxe_A0814 Bxe_A0814 Bxe_A0889 Bxe_A0889 Bxe_A0959 Bxe_A0959 pncB pncB Bxe_A1094 Bxe_A1094 Bxe_A1197 Bxe_A1197 Bxe_A1242 Bxe_A1242 Bxe_A1245 Bxe_A1245 Bxe_A1254 Bxe_A1254 Bxe_A1294 Bxe_A1294 Bxe_A1412 Bxe_A1412 Bxe_A1607 Bxe_A1607 lpxB lpxB Bxe_A1753 Bxe_A1753 Bxe_A1897 Bxe_A1897 Bxe_A1961 Bxe_A1961 Bxe_A2063 Bxe_A2063 Bxe_A2068 Bxe_A2068 Bxe_A2152 Bxe_A2152 Bxe_A2168 Bxe_A2168 Bxe_A2197 Bxe_A2197 Bxe_A2228 Bxe_A2228 Bxe_A2237 Bxe_A2237 Bxe_A2238 Bxe_A2238 Bxe_A2240 Bxe_A2240 Bxe_A2254 Bxe_A2254 Bxe_A2256 Bxe_A2256 mltG mltG Bxe_A0190 Bxe_A0190 Bxe_A2384 Bxe_A2384 Bxe_A2519 Bxe_A2519 Bxe_A2521 Bxe_A2521 Bxe_A2522 Bxe_A2522 Bxe_A2536 Bxe_A2536 Bxe_A2537 Bxe_A2537 Bxe_A2658 Bxe_A2658 glgA glgA Bxe_A3237 Bxe_A3237 upp upp Bxe_A3286 Bxe_A3286 Bxe_A3288 Bxe_A3288 Bxe_A3289 Bxe_A3289 Bxe_A3374 Bxe_A3374 Bxe_A3421 Bxe_A3421 cobT cobT lgt lgt Bxe_A3698 Bxe_A3698 Bxe_A3700 Bxe_A3700 Bxe_A3704 Bxe_A3704 Bxe_A3712 Bxe_A3712 Bxe_A3715 Bxe_A3715 Bxe_A3732 Bxe_A3732 Bxe_A3797 Bxe_A3797 Bxe_A3809 Bxe_A3809 Bxe_A3846 Bxe_A3846 Bxe_A3848 Bxe_A3848 Bxe_A3856 Bxe_A3856 Bxe_A3860 Bxe_A3860 Bxe_A3861 Bxe_A3861 Bxe_A3874 Bxe_A3874 queA queA tgt tgt apt apt Bxe_A4143 Bxe_A4143 rlpA rlpA mrdB mrdB Bxe_A4502 Bxe_A4502 Bxe_B0028 Bxe_B0028 Bxe_B0202 Bxe_B0202 Bxe_B0213 Bxe_B0213 Bxe_B0384 Bxe_B0384 Bxe_B0500 Bxe_B0500 Bxe_B0503 Bxe_B0503 Bxe_B0560 Bxe_B0560 Bxe_B0890 Bxe_B0890 Bxe_B0911 Bxe_B0911 Bxe_B1188 Bxe_B1188 glgA-2 glgA-2 Bxe_B1719 Bxe_B1719 Bxe_B1720 Bxe_B1720 Bxe_B1721 Bxe_B1721 Bxe_B1766 Bxe_B1766 Bxe_B1773 Bxe_B1773 Bxe_B1851 Bxe_B1851 Bxe_B2201 Bxe_B2201 Bxe_B2202 Bxe_B2202 Bxe_B2248 Bxe_B2248 Bxe_B2250 Bxe_B2250 ABE33734.1 ABE33734.1 Bxe_B2292 Bxe_B2292 glgE glgE glgB glgB Bxe_B2866 Bxe_B2866 purF purF Bxe_B2926 Bxe_B2926 Bxe_C0447 Bxe_C0447 Bxe_C0844 Bxe_C0844 Bxe_C0845 Bxe_C0845 Bxe_C1076 Bxe_C1076 Bxe_C1080 Bxe_C1080 Bxe_C1081 Bxe_C1081 Bxe_C1082 Bxe_C1082 Bxe_C1281 Bxe_C1281 Bxe_C1346 Bxe_C1346 ppnP ppnP Bxe_A3052 Bxe_A3052 Bxe_A2970 Bxe_A2970 Bxe_A0113 Bxe_A0113
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Bxe_A2345Protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family. (285 aa)
Bxe_A0262Hypothetical protein. (217 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (228 aa)
Bxe_A0354Putative penicillin-binding 1 (peptoglycansynthetase) transmembrane protein, MrcA. (799 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (232 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (349 aa)
ftsWCell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (426 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (372 aa)
Bxe_A0515Putative hypoxanthine phosphoribosyltransferase. (183 aa)
mtgAPutative monofunctional biosynthetic peptidoglycan transglycosylase, MtgA; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (240 aa)
Bxe_A0678Putative membrane protein. (594 aa)
Bxe_A0684Putative ADP-heptose--LPS heptosyltransferaseII. (341 aa)
Bxe_A0732Hypothetical protein. (934 aa)
Bxe_A0814Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family. (299 aa)
Bxe_A0889Putative transglycosylase SLT domain lipoprotein. (398 aa)
Bxe_A0959Conserved hypothetical protein; TPR domain present. (620 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (412 aa)
Bxe_A1094Conserved hypothetical protein. (397 aa)
Bxe_A1197Conserved hypothetical protein. (196 aa)
Bxe_A1242Trehalose 6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (486 aa)
Bxe_A1245Glycosyl transferase, group 1. (354 aa)
Bxe_A1254Putative membrane-bound lytic murein transglycosylase. (564 aa)
Bxe_A1294Conserved hypothetical protein; Pentapeptide repeat present. (242 aa)
Bxe_A1412Putative glycosyl transferases group 1. (389 aa)
Bxe_A1607Putative nucleotide phosphoribosyltransferase. (196 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (389 aa)
Bxe_A1753Putative type IV secretion system protein VirB1. (217 aa)
Bxe_A1897Putative phosphoribosyl transferase protein. (224 aa)
Bxe_A1961Putative penicillin-binding (peptidoglycan synthetase) transmembrane protein, mrcA; Citation: Meberg BM, Sailer FC, Nelson DE, YoungKD. J Bacteriol. 2001 183(20):6148-9. Denome SA, Elf PK,Henderson TA, Nelson DE, Young KD. J Bacteriol. 1999181(13):3981-93. (836 aa)
Bxe_A2063Putative (ceramide) glucosyltransferase. (386 aa)
Bxe_A2068Putative (ceramide) glycosyl transferase, family2. (424 aa)
Bxe_A2152Putative glycosyl transferase, group 1 family. (371 aa)
Bxe_A2168Hypothetical protein. (1117 aa)
Bxe_A2197Putative penicillin-binding 1 (peptidoglycansynthetase) transmembrane protein, MrcA. (838 aa)
Bxe_A2228Putative first mannosyl transferase, WbaZ; Citation: Liu,D., Haase,A.M., Lindqvist,L.,Lindberg, A.A. and Reeves,P.R.J. Bacteriol. 175 (11),3408-3413 (1993). (820 aa)
Bxe_A2237Predicted glycosyl transferase, group 1. (388 aa)
Bxe_A2238Putative glycosyl transferase, group 1. (409 aa)
Bxe_A2240Putative glycosyltransferase group 1, RfaG-like protein. (396 aa)
Bxe_A2254Sugar transferase, glycosyltransferase, group 1. (355 aa)
Bxe_A2256Trehalose 6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (470 aa)
mltGProtein of unknown function DUF175; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (345 aa)
Bxe_A0190TPR repeat protein. (601 aa)
Bxe_A2384Putative transmembrane protein. (578 aa)
Bxe_A2519Putative lipopolysaccharide core biosynthesis glycosyl transferase. (384 aa)
Bxe_A2521Putative glycosyl transferase, group 1. (385 aa)
Bxe_A2522Putative glycosyltransferase, group 1. (392 aa)
Bxe_A2536Putative first mannosyl transferase,o- antigen biosynthesis; Citation: Liu,D., Haase,A.M., Lindqvist,L.,Lindberg, A.A. and Reeves,P.R.J. Bacteriol. 175 (11),3408-3413 (1993). (407 aa)
Bxe_A2537Putative lipopolysaccharide biosynthesis- related glycosyltransferase. (468 aa)
Bxe_A2658Putative conjugal transfer protein, VirB1/TraA like protein. (217 aa)
glgAGlycogen synthase (ADP-glucose); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (486 aa)
Bxe_A3237Putative glycosyltransferase. (343 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa)
Bxe_A3286Putative lipopolysaccharide biosynthesis glycosyltransferase protein. (419 aa)
Bxe_A3288Putative lipopolysaccharide core biosynthesis glycosyltransferase protein. (375 aa)
Bxe_A3289Putative LPS biosynthesis-related protein. (358 aa)
Bxe_A3374Trehalose 6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (475 aa)
Bxe_A3421Putative lipopolysaccharide heptosyltransferase-1. (334 aa)
cobTNicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (353 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (301 aa)
Bxe_A3698Putatove 3-deoxy-D-manno-octulosonic- acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (439 aa)
Bxe_A3700Putative lipopolysaccharide heptosyltransferase-1. (333 aa)
Bxe_A3704Putative glycosyl transferase. (382 aa)
Bxe_A3712Putative glycosyl transferases group 1 protein. (419 aa)
Bxe_A3715Conserved hypothetical protein. (382 aa)
Bxe_A3732Putative undecaprenyl phosphate N- acetylglucosaminyltransferase. (366 aa)
Bxe_A3797Hypothetical protein. (1444 aa)
Bxe_A3809Putative bifunctional regulator/uracil phosphoribosyltransferase. (184 aa)
Bxe_A3846Putative glycosyltransferase. (358 aa)
Bxe_A3848Hypothetical protein. (401 aa)
Bxe_A3856Putative transferase. (404 aa)
Bxe_A3860Putative glycosyltransferase. (450 aa)
Bxe_A3861Putative glycosyltransferase. (398 aa)
Bxe_A3874Putative glycosyltransferase. (361 aa)
queAQueuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (352 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (396 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (188 aa)
Bxe_A4143Putative glycosyl transferase. (323 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (200 aa)
mrdBCell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (382 aa)
Bxe_A4502Putative exported protein. (148 aa)
Bxe_B0028Putative soluble lytic murein transglycosylase- related protein. (208 aa)
Bxe_B0202Putative glycosyltransferase. (483 aa)
Bxe_B0213Putative glycogen debranching protein. (660 aa)
Bxe_B0384Putative glycosyltransferase. (401 aa)
Bxe_B0500N-acetylmannosaminyltransferase; Belongs to the glycosyltransferase 26 family. (252 aa)
Bxe_B0503Putative glycosyltransferase. (363 aa)
Bxe_B0560Putative heptosyltransferase. (390 aa)
Bxe_B0890Putative membrane protein. (1026 aa)
Bxe_B0911TPR domain protein. (714 aa)
Bxe_B1188Putative pre-B cell enhancing-factor related protein; Belongs to the NAPRTase family. (480 aa)
glgA-2Starch (glycogen) synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (529 aa)
Bxe_B1719Hypothetical protein. (414 aa)
Bxe_B1720Putative glycosyltransferase CpsG. (378 aa)
Bxe_B1721Glycosyltransferase. (364 aa)
Bxe_B1766Hypothetical protein. (509 aa)
Bxe_B1773Hypothetical protein. (315 aa)
Bxe_B1851Hypothetical protein. (1238 aa)
Bxe_B2201Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (817 aa)
Bxe_B2202Hypothetical protein. (951 aa)
Bxe_B2248N-acetylmannosaminyltransferase; Belongs to the glycosyltransferase 26 family. (221 aa)
Bxe_B2250Putative glycosyltransferase. (384 aa)
ABE33734.1Hypothetical protein. (241 aa)
Bxe_B2292Hypothetical protein. (319 aa)
glgEPutative alpha-amylase-related protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (1146 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (736 aa)
Bxe_B2866Glycoside hydrolase, family 77. (736 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (516 aa)
Bxe_B2926Putative transglycosylase. (278 aa)
Bxe_C0447Putative type IV secretion system protein VirB1. (215 aa)
Bxe_C0844Putative glycosyltransferase. (310 aa)
Bxe_C0845Trehalose 6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (460 aa)
Bxe_C1076Putative glycosyltransferase. (433 aa)
Bxe_C1080Hypothetical protein. (417 aa)
Bxe_C1081Hypothetical protein. (411 aa)
Bxe_C1082Putative glycosyltransferase. (366 aa)
Bxe_C1281Putative glycosyl transferase. (360 aa)
Bxe_C1346Putative cyclic beta 1-2 glucan synthetase. (2868 aa)
ppnPConserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (106 aa)
Bxe_A3052Putative membrane protein, phage K related protein. (574 aa)
Bxe_A2970Putative lipopolysaccharide N- acetylglucosaminyltransferase. (550 aa)
Bxe_A0113Putative glycosyltransferase. (354 aa)
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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