(17 nodes) NAD+ binding network (Paraburkholderia xenovorans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Your Input:
	Bxe_A4037	3-hydroxyacyl-CoA dehydrogenase. (811 aa)
	lcdH	Putative 3-hydroxyacyl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (321 aa)
	cobB	Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (303 aa)
	Bxe_A2569	Hypothetical protein. (1063 aa)
	Bxe_A3184	3-hydroxyacyl-CoA dehydrogenase. (521 aa)
	Bxe_B0376	3-hydroxyacyl-CoA dehydrogenase. (283 aa)
	Bxe_C1031	3-hydroxyacyl-CoA dehydrogenase. (508 aa)
	Bxe_C0922	Putative 3-hydroxyacyl-CoA dehydrogenase. (314 aa)
	Bxe_C0888	3-hydroxyacyl-CoA dehydrogenase; Phenylacetyl-CoA pathway; Citation: Proc. Natl. Acad. Sci. U.S.A. 95 (11), 6419-6424 (1998). J. Bacteriol. 182 (2), 286-294 (2000).Environ Microbiol. 2002 Dec;4(12):824-41. (522 aa)
	Bxe_B2799	Silent information regulator protein Sir2. (282 aa)
	Bxe_B2944	3-hydroxyacyl-CoA dehydrogenase. (317 aa)
	Bxe_C0277	3-hydroxyacyl-CoA dehydrogenase. (283 aa)
	Bxe_C0280	3-hydroxyacyl-CoA dehydrogenase. (714 aa)
	Bxe_C0331	3-hydroxyacyl-CoA dehydrogenase. (269 aa)
	Bxe_A1391	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (706 aa)
	Bxe_A2274	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase. (694 aa)
	Bxe_C0596	3-hydroxyacyl-CoA dehydrogenase; Citation: J. Bacteriol. 186:3631-3639(2004). (300 aa)

Your Current Organism:

Paraburkholderia xenovorans

NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bxe_A1391	Bxe_A2274	Bxe_A1391	Bxe_A2274	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.	0.972
Bxe_A1391	Bxe_A3184	Bxe_A1391	Bxe_A3184	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.481
Bxe_A1391	Bxe_A4037	Bxe_A1391	Bxe_A4037	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.943
Bxe_A1391	Bxe_B0376	Bxe_A1391	Bxe_B0376	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.463
Bxe_A1391	Bxe_B2944	Bxe_A1391	Bxe_B2944	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.575
Bxe_A1391	Bxe_C0277	Bxe_A1391	Bxe_C0277	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.458
Bxe_A1391	Bxe_C0280	Bxe_A1391	Bxe_C0280	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.859
Bxe_A1391	Bxe_C0331	Bxe_A1391	Bxe_C0331	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.454
Bxe_A1391	Bxe_C0596	Bxe_A1391	Bxe_C0596	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase; Citation: J. Bacteriol. 186:3631-3639(2004).	0.476
Bxe_A1391	Bxe_C0888	Bxe_A1391	Bxe_C0888	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase; Phenylacetyl-CoA pathway; Citation: Proc. Natl. Acad. Sci. U.S.A. 95 (11), 6419-6424 (1998). J. Bacteriol. 182 (2), 286-294 (2000).Environ Microbiol. 2002 Dec;4(12):824-41.	0.728
Bxe_A1391	Bxe_C0922	Bxe_A1391	Bxe_C0922	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	Putative 3-hydroxyacyl-CoA dehydrogenase.	0.756
Bxe_A1391	Bxe_C1031	Bxe_A1391	Bxe_C1031	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.484
Bxe_A1391	lcdH	Bxe_A1391	Bxe_B0826	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	Putative 3-hydroxyacyl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.	0.515
Bxe_A2274	Bxe_A1391	Bxe_A2274	Bxe_A1391	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.972
Bxe_A2274	Bxe_A3184	Bxe_A2274	Bxe_A3184	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase.	0.672
Bxe_A2274	Bxe_A4037	Bxe_A2274	Bxe_A4037	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase.	0.943
Bxe_A2274	Bxe_B0376	Bxe_A2274	Bxe_B0376	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase.	0.639
Bxe_A2274	Bxe_B2944	Bxe_A2274	Bxe_B2944	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase.	0.593
Bxe_A2274	Bxe_C0277	Bxe_A2274	Bxe_C0277	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase.	0.633
Bxe_A2274	Bxe_C0280	Bxe_A2274	Bxe_C0280	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase.	0.841

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