STRINGSTRING
priA priA Bxe_A0222 Bxe_A0222 Bxe_A0308 Bxe_A0308 secA secA rhlE rhlE Bxe_A0849 Bxe_A0849 Bxe_A1202 Bxe_A1202 Bxe_A1513 Bxe_A1513 Bxe_A1652 Bxe_A1652 Bxe_A1793 Bxe_A1793 Bxe_A2189 Bxe_A2189 mfd mfd uvrB uvrB Bxe_A3295 Bxe_A3295 recG recG Bxe_A4436 Bxe_A4436 Bxe_B0141 Bxe_B0141 Bxe_B0778 Bxe_B0778 Bxe_B1153 Bxe_B1153 Bxe_B1664 Bxe_B1664
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
priAPrimosomal protein n; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (747 aa)
Bxe_A0222Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1028 aa)
Bxe_A0308ATP-dependent DNA helicase RecQ. (615 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (936 aa)
rhlEPutative ATP-dependent RNA helicase 1; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (543 aa)
Bxe_A0849Conserved hypothetical protein; Weak similarity to helicase domain proteins. (1062 aa)
Bxe_A1202Putative, plasmid-related, DNA/RNA helicase. (768 aa)
Bxe_A1513ATP-dependent helicase HrpA. (1428 aa)
Bxe_A1652Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (537 aa)
Bxe_A1793Helicase-like protein. (882 aa)
Bxe_A2189Putative ATP-dependent RNA helicase, rhlE; Belongs to the DEAD box helicase family. (523 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1160 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (701 aa)
Bxe_A3295Putative ATP-dependent RNA helicase 2; Belongs to the DEAD box helicase family. (491 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (768 aa)
Bxe_A4436ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. (467 aa)
Bxe_B0141DEAD/DEAH box helicase. (743 aa)
Bxe_B0778Putative DEAD/DEAH box helicase. (882 aa)
Bxe_B1153ATP dependent helicase, Lhr family. (1510 aa)
Bxe_B1664Putative helicase. (1150 aa)
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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