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Bxe_C1002 Bxe_C1002 Bxe_C1306 Bxe_C1306 Bxe_C1245 Bxe_C1245 Bxe_C1031 Bxe_C1031 Bxe_C1023 Bxe_C1023 Bxe_C0990 Bxe_C0990 Bxe_C0951 Bxe_C0951 Bxe_C0919 Bxe_C0919 Bxe_C0888 Bxe_C0888 Bxe_C0855 Bxe_C0855 Bxe_C0712 Bxe_C0712 Bxe_C0683 Bxe_C0683 Bxe_C0633 Bxe_C0633 Bxe_C0603 Bxe_C0603 Bxe_C0596 Bxe_C0596 Bxe_C0579 Bxe_C0579 Bxe_C0515 Bxe_C0515 Bxe_C0428 Bxe_C0428 Bxe_C0404 Bxe_C0404 Bxe_C0331 Bxe_C0331 Bxe_C0330 Bxe_C0330 Bxe_C0322 Bxe_C0322 Bxe_C0287 Bxe_C0287 Bxe_C0278 Bxe_C0278 Bxe_C0277 Bxe_C0277 Bxe_C0269 Bxe_C0269 Bxe_C0013 Bxe_C0013 Bxe_B2955 Bxe_B2955 Bxe_B2953 Bxe_B2953 Bxe_B2944 Bxe_B2944 Bxe_B2773 Bxe_B2773 Bxe_B2735 Bxe_B2735 Bxe_B2639 Bxe_B2639 Bxe_B2534 Bxe_B2534 Bxe_B2516 Bxe_B2516 Bxe_B2356 Bxe_B2356 mhpA mhpA mhpB mhpB Bxe_B2327 Bxe_B2327 Bxe_B2326 Bxe_B2326 Bxe_B2325 Bxe_B2325 Bxe_B2175 Bxe_B2175 Bxe_B2156 Bxe_B2156 Bxe_B2148 Bxe_B2148 Bxe_B2133 Bxe_B2133 Bxe_B1902 Bxe_B1902 Bxe_B1895 Bxe_B1895 Bxe_B1887 Bxe_B1887 Bxe_B1791 Bxe_B1791 Bxe_B1535 Bxe_B1535 Bxe_B1352 Bxe_B1352 Bxe_B1348 Bxe_B1348 Bxe_B1226 Bxe_B1226 Bxe_B1222 Bxe_B1222 Bxe_B1059 Bxe_B1059 Bxe_B1007 Bxe_B1007 Bxe_B0882 Bxe_B0882 Bxe_B0799 Bxe_B0799 Bxe_B0603 Bxe_B0603 Bxe_B0428 Bxe_B0428 Bxe_B0376 Bxe_B0376 Bxe_B0279 Bxe_B0279 Bxe_B0185 Bxe_B0185 Bxe_B0173 Bxe_B0173 Bxe_B0069 Bxe_B0069 Bxe_A4435 Bxe_A4435 Bxe_A4331 Bxe_A4331 Bxe_A4233 Bxe_A4233 Bxe_A4217 Bxe_A4217 hisC-3 hisC-3 fdhD-2 fdhD-2 Bxe_A3896 Bxe_A3896 Bxe_A3591 Bxe_A3591 Bxe_A3549 Bxe_A3549 Bxe_A3547 Bxe_A3547 Bxe_A3546 Bxe_A3546 Bxe_A3185 Bxe_A3185 Bxe_A3184 Bxe_A3184 Bxe_A3182 Bxe_A3182 Bxe_A3154 Bxe_A3154 Bxe_A2987 Bxe_A2987 Bxe_A2986 Bxe_A2986 Bxe_A2955 Bxe_A2955 Bxe_A2825 Bxe_A2825 Bxe_A2727 Bxe_A2727 Bxe_A2285 Bxe_A2285 Bxe_A2270 Bxe_A2270 Bxe_A2100 Bxe_A2100 amnG amnG amnH amnH amnF amnF dadA dadA hisC-2 hisC-2 Bxe_A0962 Bxe_A0962 Bxe_A0890 Bxe_A0890 katG katG Bxe_A0472 Bxe_A0472 Bxe_A0471 Bxe_A0471 Bxe_A0468 Bxe_A0468 Bxe_A0467 Bxe_A0467 Bxe_A0466 Bxe_A0466 hisC hisC Bxe_A0369 Bxe_A0369 Bxe_A0295 Bxe_A0295 Bxe_A0294 Bxe_A0294 Bxe_A0293 Bxe_A0293 Bxe_A0292 Bxe_A0292 Bxe_A0291 Bxe_A0291 Bxe_A0286 Bxe_A0286 Bxe_A0011 Bxe_A0011
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Bxe_C1002Putative hydrolase, alpha/beta fold family. (292 aa)
Bxe_C1306Putative amidase. (438 aa)
Bxe_C1245Tryptophan 2-monooxygenase. (575 aa)
Bxe_C10313-hydroxyacyl-CoA dehydrogenase. (508 aa)
Bxe_C1023Putative hydrolase, alpha/beta fold family. (287 aa)
Bxe_C0990Putative flavoprotein monooxygenase. (507 aa)
Bxe_C0951Putative FAD-dependent pyridine nucleotide- disulfide oxidoreductase. (372 aa)
Bxe_C0919Putative coenzyme F390 synthetase II. (470 aa)
Bxe_C08883-hydroxyacyl-CoA dehydrogenase; Phenylacetyl-CoA pathway; Citation: Proc. Natl. Acad. Sci. U.S.A. 95 (11), 6419-6424 (1998). J. Bacteriol. 182 (2), 286-294 (2000).Environ Microbiol. 2002 Dec;4(12):824-41. (522 aa)
Bxe_C0855Short chain enoyl-CoA hydratase. (263 aa)
Bxe_C0712Enoyl-CoA hydratase. (226 aa)
Bxe_C0683Putative hydrolase. (271 aa)
Bxe_C0633Hypothetical protein. (472 aa)
Bxe_C0603Enoyl-CoA hydratase / short chain enoyl-CoA hydratase. (267 aa)
Bxe_C05963-hydroxyacyl-CoA dehydrogenase; Citation: J. Bacteriol. 186:3631-3639(2004). (300 aa)
Bxe_C0579Putative FAD-dependent pyridine nucleotide- disulfide oxidoreductase; Citation: J. Bacteriol. 177:676-687(1995). (415 aa)
Bxe_C0515Enoyl-CoA hydratase. (266 aa)
Bxe_C0428Putative amidase; Belongs to the amidase family. (474 aa)
Bxe_C0404D-amino-acid dehydrogenase. (409 aa)
Bxe_C03313-hydroxyacyl-CoA dehydrogenase. (269 aa)
Bxe_C0330Enoyl-CoA hydratase. (260 aa)
Bxe_C0322Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
Bxe_C0287Putative enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
Bxe_C0278Enoyl-CoA hydratase. (262 aa)
Bxe_C02773-hydroxyacyl-CoA dehydrogenase. (283 aa)
Bxe_C0269Enoyl-CoA hydratase. (259 aa)
Bxe_C0013Putative monooxygenase. (519 aa)
Bxe_B2955Putative pyridoxal-dependent decarboxylase. (450 aa)
Bxe_B2953Phenylacetic acid degradation-related protein. (144 aa)
Bxe_B29443-hydroxyacyl-CoA dehydrogenase. (317 aa)
Bxe_B27734-hydroxyphenylpyruvate dioxygenase; Tyrosine degradation; Citation: J. Bacteriol. 186 (15), 5062-5077 (2004). (377 aa)
Bxe_B2735Enoyl-CoA hydratase. (264 aa)
Bxe_B2639Putative oxygenase. (515 aa)
Bxe_B2534Putative enoyl-CoA hydratase/isomerase. (241 aa)
Bxe_B2516Phenylacetic acid degradation-related protein. (135 aa)
Bxe_B2356Phenylacetic acid degradation-related protein. (144 aa)
mhpA3-hydroxyphenylpropionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). (622 aa)
mhpBPutative 2,3-dihydroxyphenylpropionate 1,2- dioxygenase (MhpB); Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family. (316 aa)
Bxe_B2327Putative 2-hydroxypenta-2,4-dienoate hydratase(MhpD); 3-hydroxyphenyl propionate pathway; Citation: Microbiology 145 (Pt 10), 2813-2820(1999). (268 aa)
Bxe_B2326Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (313 aa)
Bxe_B23254-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (338 aa)
Bxe_B2175Peptidase M20D, amidohydrolase. (396 aa)
Bxe_B2156Putative hydrolases or acyltransferases(alpha/beta hydrolase superfamily). (297 aa)
Bxe_B2148Putative hydratase/decarboxylase. (266 aa)
Bxe_B2133Putative 2-keto-4-pentenoate hydratase. (261 aa)
Bxe_B1902Putative enoyl-CoA hydratase/isomerase. (249 aa)
Bxe_B1895Putative enoyl-CoA hydratase/isomerase. (247 aa)
Bxe_B1887Putative enoyl-CoA hydratase/isomerase. (248 aa)
Bxe_B1791Membrane protein. (293 aa)
Bxe_B1535Putative flavin monoamine oxidase-related protein. (530 aa)
Bxe_B1352Phenylacetic acid degradation-related protein. (133 aa)
Bxe_B1348D-amino acid dehydrogenase small subunit. (403 aa)
Bxe_B1226Putative oxygenase. (588 aa)
Bxe_B1222Aromatic amino acid aminotransferase apoenzyme. (399 aa)
Bxe_B1059Putative amidase; Belongs to the amidase family. (405 aa)
Bxe_B1007Enoyl-CoA hydratase. (268 aa)
Bxe_B08824-hydroxyphenylpyruvate dioxygenase. (627 aa)
Bxe_B0799D-amino-acid dehydrogenase. (410 aa)
Bxe_B0603Predicted acetamidase/formamidase. (343 aa)
Bxe_B0428Putative monooxygenase. (569 aa)
Bxe_B03763-hydroxyacyl-CoA dehydrogenase. (283 aa)
Bxe_B0279Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (283 aa)
Bxe_B0185Pyridine nucleotide-disulfide oxidoreductase, class I. (421 aa)
Bxe_B0173Rieske (2Fe-2S) region. (104 aa)
Bxe_B0069Peptidase M20D, amidohydrolase. (384 aa)
Bxe_A44352-keto-4-methylthiobutyrate aminotransferase apoenzyme. (384 aa)
Bxe_A4331Amidase; Belongs to the amidase family. (522 aa)
Bxe_A4233Putative Enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (295 aa)
Bxe_A4217Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase. (321 aa)
hisC-3Aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (359 aa)
fdhD-2Formate dehydrogenase, subunit FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (279 aa)
Bxe_A3896Putative enoyl-CoA hydratase/isomerase. (274 aa)
Bxe_A3591Putative redutase. (418 aa)
Bxe_A3549HOMODA hydrolase (CmtE); P-cumate pathway; Citation: J. Bacteriol. 178 (5), 1351-1362 (1996). (301 aa)
Bxe_A3547Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (314 aa)
Bxe_A35464-hydroxy-2-ketovalerate aldolase (CmtG); Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (340 aa)
Bxe_A3185Enoyl-CoA hydratase; Citation: Olivera,E.R., Minambres,B., Garcia,B., etal. Proc. Natl. Acad. Sci. U.S.A. 95 (11), 6419- 6424(1998); Belongs to the enoyl-CoA hydratase/isomerase family. (262 aa)
Bxe_A31843-hydroxyacyl-CoA dehydrogenase. (521 aa)
Bxe_A31822-keto-4-methylthiobutyrate aminotransferase apoenzyme. (390 aa)
Bxe_A3154Aminotransferase. (399 aa)
Bxe_A2987Putative ribosomal-protein- alanine acetyltransferase, GNAT family. (193 aa)
Bxe_A2986Putative acetyltransferase protein, GNAT family. (182 aa)
Bxe_A2955Peptidase M20D, amidohydrolase. (387 aa)
Bxe_A2825Aminotransferase. (408 aa)
Bxe_A2727Putative 3-(3-hydroxy- phenyl)propionate hydroxylase (MhpA); Citation: J. Bacteriol. 179 (8), 2573-2581 (1997).J.Chem. Biol. 9 (9), 1017-1026 (2002). (570 aa)
Bxe_A2285D-amino-acid dehydrogenase. (432 aa)
Bxe_A2270Phenylacetic acid degradation-related protein. (161 aa)
Bxe_A2100Putative Asp-tRNA Asn/Glu-tRNAGln amidotransferase A subunit; Belongs to the amidase family. (374 aa)
amnG4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (345 aa)
amnHAcetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (313 aa)
amnF2-keto-4-pentenoate hydratase; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. Belongs to the hydratase/decarboxylase family. MhpD subfamily. (269 aa)
dadAD-amino-acid dehydrogenase; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family. (429 aa)
hisC-2Aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa)
Bxe_A0962Putative monooxygenase, FAD-binding protein. (574 aa)
Bxe_A0890Aminotransferase. (398 aa)
katGHaem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (753 aa)
Bxe_A0472Putative hippurate carboxypeptidase, M20D- type. (423 aa)
Bxe_A0471Short chain enoyl-CoA hydratase; Phenylacetyl-CoA pathway; Citation: Mol Microbiol. 2001 Feb;39(4):863- 74.Proc. Natl. Acad. Sci. U.S.A. 95 (11), 6419-6424 (1998).Environ Microbiol. 2002 Dec;4(12):824-41; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
Bxe_A0468Enoyl-CoA hydratase; Phenylacetyl-CoA pathway; Citation: Gene 341, 167-179 (2004). PNAS USA. 95(11), 6419-6424 (1998). Environ Microbiol. 2002Dec;4(12):824-41; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)
Bxe_A0467Phenylacetic acid degradation- related thioesterase (PaaI); Phenylacetyl-CoA pathway; Citation: Gene 341, 167-179 (2004). EnvironMicrobiol. 2002 Dec;4(12):824-41. (153 aa)
Bxe_A0466phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (434 aa)
hisCHistidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa)
Bxe_A0369D-amino-acid dehydrogenase. (421 aa)
Bxe_A0295Phenylacetic acid degradation protein PaaA; Phenylacetyl-CoA pathway; Citation: J. Bacteriol. 182 (2), 286-294 (2000).Proc. Natl. Acad. Sci. U.S.A. 95 (11), 6419-6424 (1998).J. Bacteriol. 180 (5), 1063-1071 (1998). EnvironMicrobiol. 2002 Dec;4(12):824-41. (332 aa)
Bxe_A0294Phenylacetic acid degradation protein PaaB; Phenylacetyl-CoA pathway; Citation: Mol. Genet. Genomics 267 (5), 656- 663(2002). J. Bacteriol. 187 (4), 1493-1503 (2005). FEBSLett. 406 (1-2), 23-27 (1997). Environ Microbiol. 2002Dec;4(12):824-41. (94 aa)
Bxe_A0293Phenylacetic acid degradation protein PaaC; Phenylacetyl-CoA pathway; Citation: J. Bacteriol. 182 (2), 286-294 (2000).Mol. Genet. Genomics 267 (5), 656-663 (2002). J.Bacteriol. 180 (5), 1063-1071 (1998). Environ Microbiol.2002 Dec;4(12):824-41. (267 aa)
Bxe_A0292Phenylacetic acid degradation protein PaaD; Phenylacetyl-CoA pathway; Citation: J. Bacteriol. 182 (2), 286-294 (2000). J.Bacteriol. 180 (5), 1063-1071 (1998). FEBS Lett. 406(1- 2), 23-27 (1997). Environ Microbiol. 2002Dec;4(12):824-41. (186 aa)
Bxe_A0291Phenylacetic acid degradation NADH oxidoreductase PaaE; Phenylacetyl-CoA pathway; Citation: J. Bacteriol. 182 (2), 286-294 (2000). J.Bacteriol. 180 (5), 1063-1071 (1998). Proc. Natl. Acad.Sci. U.S.A. 95 (11), 6419-6424 (1998). Environ Microbiol.2002 Dec;4(12):824-41. (362 aa)
Bxe_A02864-hydroxyphenylpyruvate dioxygenase; Tyrosine degradation; Citation: Structure Fold. Des. 7 (8), 977-988(1999). (365 aa)
Bxe_A0011Phenylalanine degradation; Citation: J. Mol. Biol. 320 (3), 645-661 (2002). (336 aa)
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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