STRINGSTRING
Bxe_A3236 Bxe_A3236 Bxe_A0089 Bxe_A0089 Bxe_A0094 Bxe_A0094 Bxe_A0177 Bxe_A0177 Bxe_A0273 Bxe_A0273 Bxe_A0363 Bxe_A0363 lpxC lpxC Bxe_A0678 Bxe_A0678 Bxe_A0684 Bxe_A0684 kdsB kdsB lpxK lpxK Bxe_A0959 Bxe_A0959 Bxe_A0987 Bxe_A0987 hldD hldD Bxe_A1159 Bxe_A1159 Bxe_A1212 Bxe_A1212 kdsA kdsA Bxe_A1589 Bxe_A1589 lpxH lpxH lpxD lpxD lpxA lpxA lpxB lpxB Bxe_A1946 Bxe_A1946 Bxe_A1962 Bxe_A1962 Bxe_A2007 Bxe_A2007 Bxe_A2010 Bxe_A2010 Bxe_A2054 Bxe_A2054 Bxe_A2152 Bxe_A2152 Bxe_A2228 Bxe_A2228 Bxe_A2237 Bxe_A2237 Bxe_A2238 Bxe_A2238 Bxe_A2384 Bxe_A2384 Bxe_A2517 Bxe_A2517 Bxe_A2519 Bxe_A2519 Bxe_A2521 Bxe_A2521 Bxe_A2522 Bxe_A2522 Bxe_A2536 Bxe_A2536 Bxe_A2660 Bxe_A2660 Bxe_A2970 Bxe_A2970 Bxe_A3286 Bxe_A3286 Bxe_A3287 Bxe_A3287 Bxe_A3288 Bxe_A3288 Bxe_A3289 Bxe_A3289 Bxe_A3291 Bxe_A3291 Bxe_A3421 Bxe_A3421 Bxe_A3698 Bxe_A3698 Bxe_A3700 Bxe_A3700 Bxe_A3714 Bxe_A3714 Bxe_A3715 Bxe_A3715 Bxe_A3723 Bxe_A3723 Bxe_A3795 Bxe_A3795 Bxe_A3846 Bxe_A3846 Bxe_A4014 Bxe_A4014 ubiB ubiB Bxe_A4117 Bxe_A4117 Bxe_A4118 Bxe_A4118 Bxe_A4145 Bxe_A4145 Bxe_A4229 Bxe_A4229 gmhA gmhA Bxe_A4372 Bxe_A4372 Bxe_B0503 Bxe_B0503 Bxe_B0560 Bxe_B0560 Bxe_B1103 Bxe_B1103 Bxe_B1720 Bxe_B1720 Bxe_B1986 Bxe_B1986 Bxe_B2053 Bxe_B2053 Bxe_B2078 Bxe_B2078 Bxe_B2250 Bxe_B2250 ABE33734.1 ABE33734.1 Bxe_C0346 Bxe_C0346 Bxe_C0347 Bxe_C0347 Bxe_C1077 Bxe_C1077 Bxe_C1082 Bxe_C1082 Bxe_C1185 Bxe_C1185
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Bxe_A3236Putative metallo-phosphoesterase. (313 aa)
Bxe_A0089Sodium/calcium antiporter. (336 aa)
Bxe_A0094Putative acetyltransferase. (210 aa)
Bxe_A0177Putative glycosyl transferase. (268 aa)
Bxe_A0273Outer membrane porin, OmpW family. (274 aa)
Bxe_A0363Outer membrane porin, OmpW family. (241 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa)
Bxe_A0678Putative membrane protein. (594 aa)
Bxe_A0684Putative ADP-heptose--LPS heptosyltransferaseII. (341 aa)
kdsB3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (289 aa)
lpxKlipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (338 aa)
Bxe_A0959Conserved hypothetical protein; TPR domain present. (620 aa)
Bxe_A0987D-alpha,beta-D-heptose 7-phosphate 1-kinase. (326 aa)
hldDADP-glyceromanno-heptose 6-epimerase precursor; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (330 aa)
Bxe_A1159Hypothetical protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family. (220 aa)
Bxe_A1212RNA-directed DNA polymerase (Reverse transcriptase). (455 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (284 aa)
Bxe_A1589RNA-directed DNA polymerase. (455 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (265 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (370 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (389 aa)
Bxe_A1946Outer membrane protein (porin), OmpW family. (218 aa)
Bxe_A1962Putative lipid A biosynthesis acyltransferase; Citation: Blattner,F.R., Plunkett,G. III,Bloch,C.A., et al Science 277 (5331), 1453-1474 (1997). (292 aa)
Bxe_A2007SpoVR-like protein; Citation: Beall,B. and Moran,C.P. Jr.. Bacteriol.176 (7), 2003-2012 (1994.Noback,M.A.,Holsappel, S.,Kiewiet,R.,Terpstra,P.Wambutt,R.,Wedler,H.,Venema,G. and Bron,S.Microbiology (Reading, Engl.) 144 (PT4), 859- 875 (1998). (552 aa)
Bxe_A2010Glycosyl transferase, family 2. (360 aa)
Bxe_A2054Aspartyl/asparaginyl beta-hydroxylase. (300 aa)
Bxe_A2152Putative glycosyl transferase, group 1 family. (371 aa)
Bxe_A2228Putative first mannosyl transferase, WbaZ; Citation: Liu,D., Haase,A.M., Lindqvist,L.,Lindberg, A.A. and Reeves,P.R.J. Bacteriol. 175 (11),3408-3413 (1993). (820 aa)
Bxe_A2237Predicted glycosyl transferase, group 1. (388 aa)
Bxe_A2238Putative glycosyl transferase, group 1. (409 aa)
Bxe_A2384Putative transmembrane protein. (578 aa)
Bxe_A2517Putative glycosyl transferase. (330 aa)
Bxe_A2519Putative lipopolysaccharide core biosynthesis glycosyl transferase. (384 aa)
Bxe_A2521Putative glycosyl transferase, group 1. (385 aa)
Bxe_A2522Putative glycosyltransferase, group 1. (392 aa)
Bxe_A2536Putative first mannosyl transferase,o- antigen biosynthesis; Citation: Liu,D., Haase,A.M., Lindqvist,L.,Lindberg, A.A. and Reeves,P.R.J. Bacteriol. 175 (11),3408-3413 (1993). (407 aa)
Bxe_A2660Putative reverse transcriptase-maturase- endonuclease. (455 aa)
Bxe_A2970Putative lipopolysaccharide N- acetylglucosaminyltransferase. (550 aa)
Bxe_A3286Putative lipopolysaccharide biosynthesis glycosyltransferase protein. (419 aa)
Bxe_A3287Hypothetical protein. (448 aa)
Bxe_A3288Putative lipopolysaccharide core biosynthesis glycosyltransferase protein. (375 aa)
Bxe_A3289Putative LPS biosynthesis-related protein. (358 aa)
Bxe_A3291Putative LPS biosynthesis-related protein. (253 aa)
Bxe_A3421Putative lipopolysaccharide heptosyltransferase-1. (334 aa)
Bxe_A3698Putatove 3-deoxy-D-manno-octulosonic- acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (439 aa)
Bxe_A3700Putative lipopolysaccharide heptosyltransferase-1. (333 aa)
Bxe_A3714D-alpha,beta-D-heptose 7-phosphate 1-kinase. (334 aa)
Bxe_A3715Conserved hypothetical protein. (382 aa)
Bxe_A3723Conserved hypothetical protein. (333 aa)
Bxe_A3795Putative glycosyl transferase. (332 aa)
Bxe_A3846Putative glycosyltransferase. (358 aa)
Bxe_A4014D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. (184 aa)
ubiB2-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (525 aa)
Bxe_A4117KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. (327 aa)
Bxe_A4118Phosphatase YrbI. (186 aa)
Bxe_A4145Putative exported protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family. (187 aa)
Bxe_A4229Cytidyltransferase-related protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (160 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (195 aa)
Bxe_A4372Putative lipid A biosynthesis lauroylacyltransferase. (294 aa)
Bxe_B0503Putative glycosyltransferase. (363 aa)
Bxe_B0560Putative heptosyltransferase. (390 aa)
Bxe_B1103Putative lipid A biosynthesis lauroylacyl transferase. (294 aa)
Bxe_B1720Putative glycosyltransferase CpsG. (378 aa)
Bxe_B1986Conserved hypothetical protein. (519 aa)
Bxe_B2053RNA-directed DNA polymerase (Reverse transcriptase). (465 aa)
Bxe_B2078Conserved hypothetical protein. (285 aa)
Bxe_B2250Putative glycosyltransferase. (384 aa)
ABE33734.1Hypothetical protein. (241 aa)
Bxe_C0346Conserved hypothetical protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family. (188 aa)
Bxe_C0347Putative membrane protein. (299 aa)
Bxe_C1077Putative glycosyltransferase. (276 aa)
Bxe_C1082Putative glycosyltransferase. (366 aa)
Bxe_C1185Outer membrane protein (porin), OmpW family. (185 aa)
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.