STRINGSTRING
Bxe_C0528 Bxe_C0528 Bxe_C0352 Bxe_C0352 Bxe_C0332 Bxe_C0332 Bxe_C0295 Bxe_C0295 Bxe_C0268 Bxe_C0268 Bxe_C0084 Bxe_C0084 Bxe_C0039 Bxe_C0039 Bxe_B3030 Bxe_B3030 Bxe_B2553 Bxe_B2553 kynB kynB Bxe_A0590 Bxe_A0590 gph gph gcvT gcvT gcvH gcvH gcvP gcvP fdhD fdhD fdhA fdhA fdhB fdhB fdhC fdhC Bxe_A1055 Bxe_A1055 Bxe_A1064 Bxe_A1064 Bxe_A1153 Bxe_A1153 Bxe_A1395 Bxe_A1395 Bxe_A1486 Bxe_A1486 Bxe_A1496 Bxe_A1496 Bxe_A1522 Bxe_A1522 Bxe_A1543 Bxe_A1543 Bxe_A1547 Bxe_A1547 Bxe_A1578 Bxe_A1578 Bxe_A1647 Bxe_A1647 Bxe_A1651 Bxe_A1651 Bxe_A1669 Bxe_A1669 Bxe_A1721 Bxe_A1721 Bxe_A1722 Bxe_A1722 Bxe_A1821 Bxe_A1821 acsA acsA Bxe_A1921 Bxe_A1921 Bxe_A1982 Bxe_A1982 Bxe_A2219 Bxe_A2219 Bxe_A2220 Bxe_A2220 Bxe_A2221 Bxe_A2221 glcB glcB Bxe_A2273 Bxe_A2273 Bxe_A2298 Bxe_A2298 Bxe_A2335 Bxe_A2335 Bxe_A2341 Bxe_A2341 Bxe_A2342 Bxe_A2342 Bxe_A2460 Bxe_A2460 Bxe_A2461 Bxe_A2461 Bxe_A2462 Bxe_A2462 Bxe_A2716 Bxe_A2716 Bxe_A2744 Bxe_A2744 Bxe_A2758 Bxe_A2758 Bxe_A2769 Bxe_A2769 Bxe_A2777 Bxe_A2777 Bxe_A2810 Bxe_A2810 Bxe_A2941 Bxe_A2941 acsA-2 acsA-2 Bxe_A3189 Bxe_A3189 Bxe_C1329 Bxe_C1329 Bxe_C1328 Bxe_C1328 Bxe_C1324 Bxe_C1324 Bxe_C1229 Bxe_C1229 merA merA Bxe_C1008 Bxe_C1008 Bxe_C0986 Bxe_C0986 Bxe_C0958 Bxe_C0958 Bxe_C0915 Bxe_C0915 Bxe_C0902 Bxe_C0902 Bxe_C0860 Bxe_C0860 Bxe_C0858 Bxe_C0858 Bxe_C0853 Bxe_C0853 Bxe_C0830 Bxe_C0830 Bxe_C0770 Bxe_C0770 Bxe_C0769 Bxe_C0769 Bxe_C0624 Bxe_C0624 Bxe_C0581 Bxe_C0581 Bxe_C0574 Bxe_C0574 Bxe_A3429 Bxe_A3429 Bxe_A3458 Bxe_A3458 Bxe_A3540 Bxe_A3540 Bxe_A3573 Bxe_A3573 Bxe_A3841 Bxe_A3841 glyA glyA Bxe_A3978 Bxe_A3978 Bxe_A3979 Bxe_A3979 Bxe_A3980 Bxe_A3980 Bxe_A3986 Bxe_A3986 purU purU Bxe_A4255 Bxe_A4255 Bxe_A4269 Bxe_A4269 Bxe_A4273 Bxe_A4273 icmF icmF Bxe_A4442 Bxe_A4442 Bxe_B0302 Bxe_B0302 Bxe_B0354 Bxe_B0354 Bxe_B0377 Bxe_B0377 Bxe_B0440 Bxe_B0440 Bxe_B0441 Bxe_B0441 Bxe_B0582 Bxe_B0582 Bxe_B0739 Bxe_B0739 Bxe_B0822 Bxe_B0822 Bxe_B0942 Bxe_B0942 Bxe_B0983 Bxe_B0983 Bxe_B1085 Bxe_B1085 Bxe_B1134 Bxe_B1134 Bxe_B1176 Bxe_B1176 Bxe_B1215 Bxe_B1215 Bxe_B1304 Bxe_B1304 Bxe_B1382 Bxe_B1382 Bxe_B1383 Bxe_B1383 Bxe_B1460 Bxe_B1460 Bxe_B1486 Bxe_B1486 Bxe_B1490 Bxe_B1490 Bxe_B1523 Bxe_B1523 Bxe_B1533 Bxe_B1533 purU-2 purU-2 glyA-2 glyA-2 Bxe_B1620 Bxe_B1620 Bxe_B1668 Bxe_B1668 Bxe_B1706 Bxe_B1706 Bxe_B1744 Bxe_B1744 Bxe_B1979 Bxe_B1979 Bxe_B2128 Bxe_B2128 Bxe_B2169 Bxe_B2169 Bxe_B2346 Bxe_B2346 Bxe_B2367 Bxe_B2367 Bxe_B2452 Bxe_B2452 cbbL cbbL gph-2 gph-2 Bxe_B2551 Bxe_B2551 Bxe_B2552 Bxe_B2552 Bxe_B2554 Bxe_B2554 Bxe_B3001 Bxe_B3001 Bxe_B2903 Bxe_B2903 mdh mdh Bxe_B2890 Bxe_B2890 Bxe_B2657 Bxe_B2657 Bxe_B2656 Bxe_B2656 Bxe_B2652 Bxe_B2652 Bxe_A0781 Bxe_A0781
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Bxe_C0528NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit. (610 aa)
Bxe_C0352Conserved hypothetical protein. (386 aa)
Bxe_C0332Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
Bxe_C0295methylmalonyl-CoA epimerase. (186 aa)
Bxe_C0268Citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (292 aa)
Bxe_C0084Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (764 aa)
Bxe_C0039Transcriptional regulator, CopG family; Transcriptional regulator. (152 aa)
Bxe_B3030Arsenate reductase. (119 aa)
Bxe_B2553Formate dehydrogenase (quinone-dependent) catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (821 aa)
kynBKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (212 aa)
Bxe_A05902-keto-3-deoxy-phosphogluconate aldolase. (213 aa)
gphPhosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (238 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (384 aa)
gcvHGlycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
gcvPGlycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (978 aa)
fdhDFormate dehydrogenase delta subunit. (83 aa)
fdhAFormate dehydrogenase alpha subunit. (982 aa)
fdhBFormate dehydrogenase beta subunit. (521 aa)
fdhCFormate dehydrogenase gamma subunit. (161 aa)
Bxe_A1055Putative 2-ketogluconate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
Bxe_A1064Putative haloacid dehalogenase-like hydrolase. (219 aa)
Bxe_A1153Putative esterase. (208 aa)
Bxe_A1395Putative acetyl-CoA synthetase. (556 aa)
Bxe_A1486Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (771 aa)
Bxe_A1496Putative pyridine nucleotide- disulphide oxidoreductase. (466 aa)
Bxe_A1522L-glutamine synthetase. (471 aa)
Bxe_A1543Dihydrolipoamide dehydrogenase. (603 aa)
Bxe_A1547Conserved hypothetical protein. (240 aa)
Bxe_A1578Conserved hypothetical protein. (246 aa)
Bxe_A1647Malate synthase A; Belongs to the malate synthase family. (536 aa)
Bxe_A1651Isocitrate lyase. (434 aa)
Bxe_A1669Conserved hypothetical protein ArsC-like protein; Belongs to the ArsC family. (121 aa)
Bxe_A1721Excisionase/Xis, DNA-binding protein. (404 aa)
Bxe_A1722Predicted metal-dependent hydrolase. (342 aa)
Bxe_A1821Putative esterase/lipase/thioesterase. (328 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa)
Bxe_A1921Murein tetrapeptidase LD-carboxypeptidase, Serine peptidase, MEROPS family S66. (308 aa)
Bxe_A1982Putative 2-ketogluconate 6-phosphate reductase, TkrA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
Bxe_A2219Glycolate oxidase subunit GlcD. (499 aa)
Bxe_A2220Putative glycolate oxidase, subunit GlcE. (355 aa)
Bxe_A2221Putative glycolate oxidase iron-sulfur subunit, GlcF. (413 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (724 aa)
Bxe_A2273Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Bxe_A2298Glycerate kinase; Belongs to the glycerate kinase type-1 family. (381 aa)
Bxe_A23353-ketoacyl-CoA thiolase / acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
Bxe_A23413-oxoacyl-[acyl-carrier-protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
Bxe_A2342acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Bxe_A2460Glyoxylate carboligase; Belongs to the TPP enzyme family. (591 aa)
Bxe_A2461Hydroxypyruvate isomerase; Belongs to the hyi family. (269 aa)
Bxe_A24622-hydroxy-3-oxopropionate reductase. (302 aa)
Bxe_A2716Putative citrate synthase. (418 aa)
Bxe_A2744Putative thiolase/acetyl-CoA acetyltransferase, PaaJ-like protein. (406 aa)
Bxe_A2758Putative citrate lyase beta chain (acyl lyase subunit); Belongs to the HpcH/HpaI aldolase family. (290 aa)
Bxe_A2769Putative acetyl-CoA synthetase and ligase. (650 aa)
Bxe_A27773-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (433 aa)
Bxe_A2810Dihydrolipoamide dehydrogenase. (476 aa)
Bxe_A2941N-formylglutamate deformylase. (271 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
Bxe_A3189Putative nodulation-related acyl dehydratase, MaoC/NodN-like protein. (158 aa)
Bxe_C1329Conserved hypothetical protein. (205 aa)
Bxe_C1328Conserved hypothetical protein. (211 aa)
Bxe_C1324Conserved hypothetical protein. (224 aa)
Bxe_C1229Tartrate dehydrogenase. (364 aa)
merAPutative mercuric ion reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (561 aa)
Bxe_C1008Citrate synthase. (429 aa)
Bxe_C0986Putative citrate synthase. (259 aa)
Bxe_C0958Hydroxypyruvate isomerase; Belongs to the hyi family. (267 aa)
Bxe_C0915Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Bxe_C0902Putative dehydrogenase. (301 aa)
Bxe_C0860Putative thiolase. (384 aa)
Bxe_C0858Putative dehydratase. (127 aa)
Bxe_C0853Dihydrolipoamide dehydrogenase. (465 aa)
Bxe_C0830Citrate lyase; Belongs to the HpcH/HpaI aldolase family. (282 aa)
Bxe_C0770Putative dehydrogenase. (307 aa)
Bxe_C0769Tartrate dehydrogenase. (362 aa)
Bxe_C0624Putative esterase. (296 aa)
Bxe_C0581Conserved hypothetical protein; Citation: J. Bacteriol. 182:3784-3793(2000). (395 aa)
Bxe_C0574Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (265 aa)
Bxe_A3429Hypothetical protein. (178 aa)
Bxe_A3458Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (353 aa)
Bxe_A3540Hypothetical protein. (392 aa)
Bxe_A3573Putative AMP-binding enzyme. (574 aa)
Bxe_A3841Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (760 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
Bxe_A3978D-lactate dehydrogenase (cytochrome). (497 aa)
Bxe_A3979Putative glycolate oxidase, subunit GlcE. (362 aa)
Bxe_A3980Putative glycolate oxidase iron-sulfur subunit. (408 aa)
Bxe_A3986Catalase; Belongs to the catalase family. (484 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
Bxe_A4255Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Bxe_A4269Putative 2-hydroxyacid dehydrogenase. (313 aa)
Bxe_A4273Hypothetical protein. (159 aa)
icmFMethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly (By similarity). Does not exhibit methylmalonyl- CoA mutase (MCM) activity. (1272 aa)
Bxe_A4442Conserved hypothetical protein. (131 aa)
Bxe_B0302Arsenate reductase. (140 aa)
Bxe_B03543-oxoacyl-[acyl-carrier-protein] reductase. (240 aa)
Bxe_B03773-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
Bxe_B0440Putative lactoylglutathione lyase. (179 aa)
Bxe_B0441Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; Belongs to the RuBisCO large chain family. (432 aa)
Bxe_B0582Putative dihydrolipoamide dehydrogenase. (474 aa)
Bxe_B0739Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
Bxe_B0822HAD-superfamily hydrolase, subfamily IA, variant3. (224 aa)
Bxe_B0942L-glutamine synthetase. (444 aa)
Bxe_B0983Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
Bxe_B1085AMP-binding enzyme. (563 aa)
Bxe_B1134Citrate synthase; Belongs to the citrate synthase family. (432 aa)
Bxe_B1176Putative oxidoreductase. (247 aa)
Bxe_B1215Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (707 aa)
Bxe_B1304Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (786 aa)
Bxe_B1382Conserved hypothetical protein. (251 aa)
Bxe_B1383Conserved hypothetical protein. (218 aa)
Bxe_B1460Nitrogenase-associated protein; Belongs to the ArsC family. (161 aa)
Bxe_B1486Tartrate dehydrogenase. (360 aa)
Bxe_B1490D-isomer specific 2-hydroxyacid dehydrogenase. (308 aa)
Bxe_B1523Putative dehydrogenase. (297 aa)
Bxe_B1533Aconitase; Belongs to the aconitase/IPM isomerase family. (861 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (291 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
Bxe_B1620Tartrate dehydrogenase. (368 aa)
Bxe_B1668Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (363 aa)
Bxe_B1706Formamidase (FmdA); Citation: Eur. J. Biochem. 240 (2), 314-322 (1996). (410 aa)
Bxe_B1744Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
Bxe_B1979Putative dehydrogenase. (316 aa)
Bxe_B2128Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
Bxe_B2169Hydroxypyruvate isomerase; Belongs to the hyi family. (262 aa)
Bxe_B2346Putative dehydrogenase. (335 aa)
Bxe_B2367Conserved hypothetical protein. (393 aa)
Bxe_B2452Ribulose 1,5-bisphosphate carboxylase small subunit. (142 aa)
cbbLRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (499 aa)
gph-2Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (228 aa)
Bxe_B2551Formate dehydrogenase (quinone-dependent) cytochrome b subunit. (218 aa)
Bxe_B2552Formate dehydrogenase (quinone-dependent) iron-sulfur subunit. (310 aa)
Bxe_B2554Formate dehydrogenase (quinone-dependent) catalytic subunit. (214 aa)
Bxe_B3001Serine--glyoxylate transaminase. (406 aa)
Bxe_B2903Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
Bxe_B2890Citrate synthase; Belongs to the citrate synthase family. (433 aa)
Bxe_B2657Conserved hypothetical protein. (204 aa)
Bxe_B2656Hypothetical protein. (211 aa)
Bxe_B2652Conserved hypothetical protein. (222 aa)
Bxe_A0781Bifunctional -- transcriptional regulator, MerR family / Citrate synthase. (545 aa)
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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