STRINGSTRING
Bxe_A3841 Bxe_A3841 Bxe_A0015 Bxe_A0015 Bxe_A0052 Bxe_A0052 gcvP gcvP gcvH gcvH gcvT gcvT Bxe_A0090 Bxe_A0090 Bxe_A0180 Bxe_A0180 Bxe_A0283 Bxe_A0283 Bxe_A0463 Bxe_A0463 Bxe_A0531 Bxe_A0531 Bxe_A0532 Bxe_A0532 Bxe_A0557 Bxe_A0557 Bxe_A0565 Bxe_A0565 Bxe_A0566 Bxe_A0566 Bxe_A0588 Bxe_A0588 edd edd Bxe_A0590 Bxe_A0590 Bxe_A0592 Bxe_A0592 Bxe_A0596 Bxe_A0596 Bxe_A0613 Bxe_A0613 sucC sucC sucD sucD pgk pgk Bxe_A0690 Bxe_A0690 Bxe_A0691 Bxe_A0691 flhA flhA fghA fghA Bxe_A0781 Bxe_A0781 Bxe_A0797 Bxe_A0797 Bxe_A0833 Bxe_A0833 Bxe_A0886 Bxe_A0886 fbp1 fbp1 fdhD fdhD fdhA fdhA fdhB fdhB fdhC fdhC serC serC fumC fumC Bxe_A1316 Bxe_A1316 Bxe_A1330 Bxe_A1330 Bxe_A1389 Bxe_A1389 Bxe_A1391 Bxe_A1391 Bxe_A1395 Bxe_A1395 Bxe_A1452 Bxe_A1452 Bxe_A1486 Bxe_A1486 Bxe_A1496 Bxe_A1496 folD folD Bxe_A1541 Bxe_A1541 Bxe_A1542 Bxe_A1542 Bxe_A1543 Bxe_A1543 eno eno Bxe_A1578 Bxe_A1578 Bxe_A1621 Bxe_A1621 accA accA Bxe_A1647 Bxe_A1647 Bxe_A1651 Bxe_A1651 Bxe_A1653 Bxe_A1653 Bxe_A1669 Bxe_A1669 Bxe_A1699 Bxe_A1699 Bxe_A1721 Bxe_A1721 acsA acsA Bxe_A1875 Bxe_A1875 Bxe_A1921 Bxe_A1921 Bxe_A1980 Bxe_A1980 Bxe_A1993 Bxe_A1993 ilvA ilvA Bxe_A2133 Bxe_A2133 fabV fabV glcB glcB Bxe_A2273 Bxe_A2273 Bxe_A2274 Bxe_A2274 pgi pgi Bxe_A2315 Bxe_A2315 Bxe_A2331 Bxe_A2331 Bxe_A2335 Bxe_A2335 Bxe_A2336 Bxe_A2336 Bxe_A2341 Bxe_A2341 Bxe_A2342 Bxe_A2342 rpiA rpiA Bxe_A2716 Bxe_A2716 Bxe_A2744 Bxe_A2744 Bxe_A2758 Bxe_A2758 Bxe_A2769 Bxe_A2769 Bxe_A2777 Bxe_A2777 Bxe_A2810 Bxe_A2810 Bxe_A2811 Bxe_A2811 Bxe_A2812 Bxe_A2812 acsA-2 acsA-2 Bxe_A3136 Bxe_A3136 Bxe_A3150 Bxe_A3150 Bxe_A3184 Bxe_A3184 Bxe_A3186 Bxe_A3186 Bxe_A3189 Bxe_A3189 Bxe_A3191 Bxe_A3191 tpiA tpiA Bxe_A3304 Bxe_A3304 tal tal Bxe_A3355 Bxe_A3355 ppc ppc zwf zwf pgl pgl glk glk Bxe_A3458 Bxe_A3458 Bxe_A3540 Bxe_A3540 Bxe_A3573 Bxe_A3573 Bxe_A3576 Bxe_A3576 glyA glyA Bxe_A3986 Bxe_A3986 Bxe_A4037 Bxe_A4037 ilvA-2 ilvA-2 Bxe_A4059 Bxe_A4059 prs prs gpmA gpmA Bxe_A4255 Bxe_A4255 Bxe_A4257 Bxe_A4257 Bxe_A4273 Bxe_A4273 icmF icmF Bxe_A4423 Bxe_A4423 Bxe_A4442 Bxe_A4442 Bxe_A4472 Bxe_A4472 Bxe_B0082 Bxe_B0082 zwf-2 zwf-2 Bxe_B0216 Bxe_B0216 Bxe_B0292 Bxe_B0292 Bxe_B0302 Bxe_B0302 Bxe_B0315 Bxe_B0315 Bxe_B0354 Bxe_B0354 ackA ackA Bxe_B0357 Bxe_B0357 Bxe_B0376 Bxe_B0376 Bxe_B0377 Bxe_B0377 Bxe_B0397 Bxe_B0397 Bxe_B0403 Bxe_B0403 Bxe_B0423 Bxe_B0423 Bxe_B0440 Bxe_B0440 Bxe_B0441 Bxe_B0441 Bxe_B0443 Bxe_B0443 Bxe_B0532 Bxe_B0532 Bxe_B0582 Bxe_B0582 Bxe_B0611 Bxe_B0611 Bxe_B0616 Bxe_B0616 pta pta Bxe_B0739 Bxe_B0739 gpmA-2 gpmA-2 Bxe_B0983 Bxe_B0983 Bxe_B1057 Bxe_B1057 Bxe_B1058 Bxe_B1058 Bxe_B1085 Bxe_B1085 Bxe_B1086 Bxe_B1086 Bxe_B1134 Bxe_B1134 Bxe_B1140 Bxe_B1140 Bxe_B1215 Bxe_B1215 ABE34666.1 ABE34666.1 Bxe_B1304 Bxe_B1304 Bxe_B1309 Bxe_B1309 Bxe_B1334 Bxe_B1334 Bxe_B1341 Bxe_B1341 ackA-2 ackA-2 Bxe_B1374 Bxe_B1374 Bxe_B1382 Bxe_B1382 Bxe_B1383 Bxe_B1383 Bxe_B1432 Bxe_B1432 Bxe_B1460 Bxe_B1460 Bxe_B1533 Bxe_B1533 Bxe_B1555 Bxe_B1555 Bxe_B1581 Bxe_B1581 Bxe_B1582 Bxe_B1582 glyA-2 glyA-2 fdsA fdsA Bxe_B1601 Bxe_B1601 Bxe_B1668 Bxe_B1668 Bxe_B1701 Bxe_B1701 Bxe_B1706 Bxe_B1706 zwf-3 zwf-3 Bxe_B1784 Bxe_B1784 Bxe_B1847 Bxe_B1847 Bxe_B1848 Bxe_B1848 Bxe_B1860 Bxe_B1860 vapC vapC Bxe_B1896 Bxe_B1896 Bxe_B2023 Bxe_B2023 Bxe_B2089 Bxe_B2089 Bxe_B2109 Bxe_B2109 Bxe_B2153 Bxe_B2153 Bxe_B2210 Bxe_B2210 Bxe_B2247 Bxe_B2247 Bxe_B2367 Bxe_B2367 mtdB mtdB orfY orfY mch mch fae fae Bxe_B2446 Bxe_B2446 Bxe_B2447 Bxe_B2447 Bxe_B2448 Bxe_B2448 Bxe_B2449 Bxe_B2449 fbp2 fbp2 Bxe_B2452 Bxe_B2452 cbbL cbbL fhcB fhcB fhcA fhcA fhcD fhcD fhcC fhcC Bxe_B2551 Bxe_B2551 Bxe_B2552 Bxe_B2552 Bxe_B2553 Bxe_B2553 Bxe_B2554 Bxe_B2554 Bxe_B2559 Bxe_B2559 Bxe_B2585 Bxe_B2585 Bxe_B2644 Bxe_B2644 Bxe_B2652 Bxe_B2652 Bxe_B2656 Bxe_B2656 Bxe_B2657 Bxe_B2657 Bxe_B2659 Bxe_B2659 Bxe_B2699 Bxe_B2699 accD accD Bxe_B2890 Bxe_B2890 Bxe_B2891 Bxe_B2891 Bxe_B2892 Bxe_B2892 Bxe_B2893 Bxe_B2893 Bxe_B2894 Bxe_B2894 Bxe_B2895 Bxe_B2895 mdh mdh Bxe_B2903 Bxe_B2903 Bxe_B2944 Bxe_B2944 Bxe_B3001 Bxe_B3001 Bxe_B3030 Bxe_B3030 Bxe_C0039 Bxe_C0039 ackA-3 ackA-3 Bxe_C0052 Bxe_C0052 Bxe_C0056 Bxe_C0056 Bxe_C0084 Bxe_C0084 Bxe_C0121 Bxe_C0121 Bxe_C0241 Bxe_C0241 Bxe_C0244 Bxe_C0244 Bxe_C0268 Bxe_C0268 Bxe_C0277 Bxe_C0277 Bxe_C0280 Bxe_C0280 Bxe_C0295 Bxe_C0295 Bxe_C0331 Bxe_C0331 Bxe_C0332 Bxe_C0332 Bxe_C0352 Bxe_C0352 vapC-2 vapC-2 Bxe_C0528 Bxe_C0528 pgl-2 pgl-2 Bxe_C0574 Bxe_C0574 Bxe_C0575 Bxe_C0575 Bxe_C0581 Bxe_C0581 Bxe_C0596 Bxe_C0596 Bxe_C0643 Bxe_C0643 Bxe_C0656 Bxe_C0656 Bxe_C0679 Bxe_C0679 Bxe_C0686 Bxe_C0686 Bxe_C0702 Bxe_C0702 Bxe_C0748 Bxe_C0748 Bxe_C0763 Bxe_C0763 Bxe_C0830 Bxe_C0830 Bxe_C0853 Bxe_C0853 Bxe_C0854 Bxe_C0854 Bxe_C0858 Bxe_C0858 Bxe_C0860 Bxe_C0860 Bxe_C0888 Bxe_C0888 Bxe_C0908 Bxe_C0908 Bxe_C0915 Bxe_C0915 Bxe_C0969 Bxe_C0969 Bxe_C0986 Bxe_C0986 Bxe_C1008 Bxe_C1008 Bxe_C1031 Bxe_C1031 Bxe_C1034 Bxe_C1034 Bxe_C1063 Bxe_C1063 merA merA Bxe_C1233 Bxe_C1233 Bxe_C1265 Bxe_C1265 Bxe_C1324 Bxe_C1324 Bxe_C1328 Bxe_C1328 Bxe_C1329 Bxe_C1329 Bxe_C1331 Bxe_C1331
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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Bxe_A3841Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (760 aa)
Bxe_A0015Methylmalonate-semialdehyde dehydrogenase (acylating). (512 aa)
Bxe_A0052L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (462 aa)
gcvPGlycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (978 aa)
gcvHGlycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (384 aa)
Bxe_A0090Nonspecific acid phosphatase precursor. (358 aa)
Bxe_A01805,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (276 aa)
Bxe_A0283Malate dehydrogenase (oxaloacetatedecarboxylating) (NADP+)., Phosphate acetyltransferase; Belongs to the malic enzymes family. (760 aa)
Bxe_A0463Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
Bxe_A0531Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (461 aa)
Bxe_A0532Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa)
Bxe_A0557Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+)., Phosphate acetyltransferase. (779 aa)
Bxe_A0565Transketolase; Belongs to the transketolase family. (662 aa)
Bxe_A0566Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
Bxe_A0588Transcriptional regulator, RpiR family. (273 aa)
edd6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (634 aa)
Bxe_A05902-keto-3-deoxy-phosphogluconate aldolase. (213 aa)
Bxe_A0592Gluconate kinase, SKI family. (165 aa)
Bxe_A0596Glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (440 aa)
Bxe_A0613Phosphoglycerate mutase. (223 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
Bxe_A0690Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
Bxe_A0691Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
flhAGlutathione-dependent formaldehyde dehydrogenase(FlhA); Function confirmed by biochemical assay & mutantanalysis; Citation: J Bacteriol, 186:2173-2178; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (368 aa)
fghAS-Formylglutathione hydrolase (FghA); Serine hydrolase involved in the detoxification of formaldehyde. (285 aa)
Bxe_A0781Bifunctional -- transcriptional regulator, MerR family / Citrate synthase. (545 aa)
Bxe_A0797Isocitrate dehydrogenase (NADP). (418 aa)
Bxe_A0833Transcriptional regulator, RpiR family. (327 aa)
Bxe_A0886Serine/threonine dehydratase. (321 aa)
fbp1D-fructose 1,6-bisphosphatase. (338 aa)
fdhDFormate dehydrogenase delta subunit. (83 aa)
fdhAFormate dehydrogenase alpha subunit. (982 aa)
fdhBFormate dehydrogenase beta subunit. (521 aa)
fdhCFormate dehydrogenase gamma subunit. (161 aa)
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (348 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
Bxe_A1316Putative iron-containing alcohol dehydrogenase. (382 aa)
Bxe_A1330Transcriptional regulator, RpiR family. (278 aa)
Bxe_A1389acyl-CoA dehydrogenase. (376 aa)
Bxe_A13913-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (706 aa)
Bxe_A1395Putative acetyl-CoA synthetase. (556 aa)
Bxe_A14522,4-dienoyl-CoA reductase. (681 aa)
Bxe_A1486Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (771 aa)
Bxe_A1496Putative pyridine nucleotide- disulphide oxidoreductase. (466 aa)
folD5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
Bxe_A15412-oxo-acid dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (898 aa)
Bxe_A1542Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (555 aa)
Bxe_A1543Dihydrolipoamide dehydrogenase. (603 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
Bxe_A1578Conserved hypothetical protein. (246 aa)
Bxe_A1621Serine O-acetyltransferase. (281 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa)
Bxe_A1647Malate synthase A; Belongs to the malate synthase family. (536 aa)
Bxe_A1651Isocitrate lyase. (434 aa)
Bxe_A1653Putative acyl-CoA-binding protein. (89 aa)
Bxe_A1669Conserved hypothetical protein ArsC-like protein; Belongs to the ArsC family. (121 aa)
Bxe_A1699Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (800 aa)
Bxe_A1721Excisionase/Xis, DNA-binding protein. (404 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa)
Bxe_A1875Carbamate kinase; Belongs to the carbamate kinase family. (303 aa)
Bxe_A1921Murein tetrapeptidase LD-carboxypeptidase, Serine peptidase, MEROPS family S66. (308 aa)
Bxe_A1980Putative sugar (2-ketogluconate) kinase, PfkB family. (327 aa)
Bxe_A1993Predicted P-loop ATPase protein. (205 aa)
ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (524 aa)
Bxe_A2133Putative nonspecific acid phosphatase, NapD-like protein. (352 aa)
fabVHypothetical short-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (398 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (724 aa)
Bxe_A2273Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Bxe_A2274Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase. (694 aa)
pgiGlucose-6-phosphate isomerase. (540 aa)
Bxe_A2315Putative amino-acid dehydratase. (344 aa)
Bxe_A2331Phosphoserine phosphatase. (279 aa)
Bxe_A23353-ketoacyl-CoA thiolase / acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
Bxe_A2336Sugar kinase, ribokinase family. (316 aa)
Bxe_A23413-oxoacyl-[acyl-carrier-protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
Bxe_A2342acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa)
Bxe_A2716Putative citrate synthase. (418 aa)
Bxe_A2744Putative thiolase/acetyl-CoA acetyltransferase, PaaJ-like protein. (406 aa)
Bxe_A2758Putative citrate lyase beta chain (acyl lyase subunit); Belongs to the HpcH/HpaI aldolase family. (290 aa)
Bxe_A2769Putative acetyl-CoA synthetase and ligase. (650 aa)
Bxe_A27773-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (433 aa)
Bxe_A2810Dihydrolipoamide dehydrogenase. (476 aa)
Bxe_A28112-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (427 aa)
Bxe_A28122-oxoglutarate dehydrogenase E1 component. (953 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
Bxe_A3136Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (520 aa)
Bxe_A3150Oxidase-dependent Fe2+ Transporter, (OFeT)Family, FTR1-like protein. (281 aa)
Bxe_A31843-hydroxyacyl-CoA dehydrogenase. (521 aa)
Bxe_A3186Putative phosphoglycerate mutase. (238 aa)
Bxe_A3189Putative nodulation-related acyl dehydratase, MaoC/NodN-like protein. (158 aa)
Bxe_A3191Putative pimeloyl-CoA dehydrogenase (small subunit), PimD-like protein; Citation: Larimer,F.W., Chain,P., Hauser,L., et al.Nat. Biotechnol. 22 (1), 55-61 (2004). (375 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
Bxe_A3304Hypothetical protein. (385 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa)
Bxe_A3355Malate dehydrogenase (oxaloacetatedecarboxylating) (NADP+), Phosphate acetyltransferase. (772 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (994 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (487 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (235 aa)
glkGlucokinase; In the N-terminal section; belongs to the bacterial glucokinase family. (638 aa)
Bxe_A3458Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (353 aa)
Bxe_A3540Hypothetical protein. (392 aa)
Bxe_A3573Putative AMP-binding enzyme. (574 aa)
Bxe_A3576Methylmalonate-semialdehyde dehydrogenase (acylating). (524 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
Bxe_A3986Catalase; Belongs to the catalase family. (484 aa)
Bxe_A40373-hydroxyacyl-CoA dehydrogenase. (811 aa)
ilvA-2L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (535 aa)
Bxe_A4059Transcriptional regulator, RpiR family. (295 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
Bxe_A4255Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Bxe_A4257Putative acyl-CoA dehydrogenase. (376 aa)
Bxe_A4273Hypothetical protein. (159 aa)
icmFMethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly (By similarity). Does not exhibit methylmalonyl- CoA mutase (MCM) activity. (1272 aa)
Bxe_A4423Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (363 aa)
Bxe_A4442Conserved hypothetical protein. (131 aa)
Bxe_A44722-oxo-acid dehydrogenase E1 component homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (913 aa)
Bxe_B0082L-serine ammonia-lyase. (489 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (535 aa)
Bxe_B0216Putative polyphosphate glucokinase. (266 aa)
Bxe_B0292Acetyl-CoA hydrolase. (510 aa)
Bxe_B0302Arsenate reductase. (140 aa)
Bxe_B0315Putative acetoin dehydrogenase. (370 aa)
Bxe_B03543-oxoacyl-[acyl-carrier-protein] reductase. (240 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
Bxe_B0357Phosphate butyryltransferase. (467 aa)
Bxe_B03763-hydroxyacyl-CoA dehydrogenase. (283 aa)
Bxe_B03773-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
Bxe_B0397Acetyl-CoA hydrolase. (504 aa)
Bxe_B0403Conserved hypothetical protein. (135 aa)
Bxe_B0423Transcriptional regulator, RpiR family. (287 aa)
Bxe_B0440Putative lactoylglutathione lyase. (179 aa)
Bxe_B0441Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; Belongs to the RuBisCO large chain family. (432 aa)
Bxe_B0443Glucose 1-dehydrogenase. (266 aa)
Bxe_B0532Isocitrate dehydrogenase NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (742 aa)
Bxe_B0582Putative dihydrolipoamide dehydrogenase. (474 aa)
Bxe_B0611Gluconolactonase. (312 aa)
Bxe_B0616Serine O-acetyltransferase. (308 aa)
ptaPhosphotransacetylase; Citation: Biochem J. 2003 Jan 15;369(Pt 2):275-85. (345 aa)
Bxe_B0739Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
gpmA-2Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (240 aa)
Bxe_B0983Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
Bxe_B1057Putative alcohol dehydrogenase. (397 aa)
Bxe_B1058Conserved hypothetical protein. (129 aa)
Bxe_B1085AMP-binding enzyme. (563 aa)
Bxe_B1086Methylmalonate-semialdehyde dehydrogenase (acylating). (503 aa)
Bxe_B1134Citrate synthase; Belongs to the citrate synthase family. (432 aa)
Bxe_B1140Transcriptional regulator, RpiR family. (284 aa)
Bxe_B1215Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (707 aa)
ABE34666.1Hypothetical protein. (69 aa)
Bxe_B1304Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (786 aa)
Bxe_B1309Transketolase; Belongs to the transketolase family. (694 aa)
Bxe_B1334Fructose-bisphosphate aldolase. (339 aa)
Bxe_B13416-phosphogluconate dehydrogenase (decarboxylating). (345 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (388 aa)
Bxe_B1374Conserved hypothetical protein. (128 aa)
Bxe_B1382Conserved hypothetical protein. (251 aa)
Bxe_B1383Conserved hypothetical protein. (218 aa)
Bxe_B1432D-isomer specific 2-hydroxy acid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
Bxe_B1460Nitrogenase-associated protein; Belongs to the ArsC family. (161 aa)
Bxe_B1533Aconitase; Belongs to the aconitase/IPM isomerase family. (861 aa)
Bxe_B1555Serine O-acetyltransferase. (325 aa)
Bxe_B1581Putative membrane protein. (637 aa)
Bxe_B1582NADH-flavin oxidoreductase / NADH oxidase family protein. (687 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
fdsAGlutathione-independent formaldehyde dehydrogenase; Function confirmed by biochemical assay & mutantanalysis; Citation: J Bacteriol, 186:2173-2178. (399 aa)
Bxe_B1601L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (464 aa)
Bxe_B1668Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (363 aa)
Bxe_B1701Putative exported protein. (291 aa)
Bxe_B1706Formamidase (FmdA); Citation: Eur. J. Biochem. 240 (2), 314-322 (1996). (410 aa)
zwf-3Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (495 aa)
Bxe_B1784Putative transcriptional regulator, RpiR family. (298 aa)
Bxe_B1847Malonate decarboxylase, beta subunit. (300 aa)
Bxe_B1848Putative malonate decarboxylase gamma subunit. (272 aa)
Bxe_B1860Acetyl-CoA hydrolase. (504 aa)
vapCPilT-type plasmid stability protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (140 aa)
Bxe_B1896Putative D-isomer specific 2- hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
Bxe_B2023Methylmalonate-semialdehyde dehydrogenase (acylating). (507 aa)
Bxe_B2089Conserved hypothetical protein. (850 aa)
Bxe_B2109Putative esterase. (280 aa)
Bxe_B2153Gluconolactonase. (323 aa)
Bxe_B22106-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (469 aa)
Bxe_B2247Putative hexapeptide transferase family protein. (136 aa)
Bxe_B2367Conserved hypothetical protein. (393 aa)
mtdBMethylene-tetrahydromethanopterin dehydrogenase(NAD+/NADP+) (mtdB); Function confirmed by biochemical assay & mutantanalysis; Citation: J Bacteriol, 186:2173-2178. (313 aa)
orfYConserved hypothetical protein; Required for methylotrophy. (402 aa)
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family. (343 aa)
faeFormaldehyde-activating enzyme. (169 aa)
Bxe_B2446Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (239 aa)
Bxe_B2447Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (345 aa)
Bxe_B2448Transketolase; Belongs to the transketolase family. (680 aa)
Bxe_B2449Phosphoribulokinase. (290 aa)
fbp2D-fructose 1,6-bisphosphatase. (378 aa)
Bxe_B2452Ribulose 1,5-bisphosphate carboxylase small subunit. (142 aa)
cbbLRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (499 aa)
fhcBFormylmethanofuran dehydrogenase, subunit B. (466 aa)
fhcAFormylmethanofuran dehydrogenase, subunit A. (566 aa)
fhcDFormylmethanofuran-tetrahydromethanopterin formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family. (319 aa)
fhcCFormylmethanofuran dehydrogenase, subunit C. (281 aa)
Bxe_B2551Formate dehydrogenase (quinone-dependent) cytochrome b subunit. (218 aa)
Bxe_B2552Formate dehydrogenase (quinone-dependent) iron-sulfur subunit. (310 aa)
Bxe_B2553Formate dehydrogenase (quinone-dependent) catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (821 aa)
Bxe_B2554Formate dehydrogenase (quinone-dependent) catalytic subunit. (214 aa)
Bxe_B2559Homodimeric dihydroxyacetone kinase. (567 aa)
Bxe_B2585Conserved hypothetical protein. (280 aa)
Bxe_B2644Pyruvate phosphate dikinase. (543 aa)
Bxe_B2652Conserved hypothetical protein. (222 aa)
Bxe_B2656Hypothetical protein. (211 aa)
Bxe_B2657Conserved hypothetical protein. (204 aa)
Bxe_B2659Transcriptional regulator, RpiR family. (314 aa)
Bxe_B2699Transketolase subunit B. (288 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
Bxe_B2890Citrate synthase; Belongs to the citrate synthase family. (433 aa)
Bxe_B2891Conserved hypothetical protein. (90 aa)
Bxe_B2892Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (234 aa)
Bxe_B2893Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (591 aa)
Bxe_B2894Succinate dehydrogenase subunit D. (122 aa)
Bxe_B2895Succinate dehydrogenase subunit C. (137 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
Bxe_B2903Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
Bxe_B29443-hydroxyacyl-CoA dehydrogenase. (317 aa)
Bxe_B3001Serine--glyoxylate transaminase. (406 aa)
Bxe_B3030Arsenate reductase. (119 aa)
Bxe_C0039Transcriptional regulator, CopG family; Transcriptional regulator. (152 aa)
ackA-3Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
Bxe_C0052Phosphate butyryltransferase. (468 aa)
Bxe_C0056L-threonine ammonia-lyase. (344 aa)
Bxe_C0084Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (764 aa)
Bxe_C0121Serine O-acetyltransferase. (327 aa)
Bxe_C0241Cysteine synthase. (315 aa)
Bxe_C0244Methylmalonate-semialdehyde dehydrogenase (acylating). (508 aa)
Bxe_C0268Citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (292 aa)
Bxe_C02773-hydroxyacyl-CoA dehydrogenase. (283 aa)
Bxe_C02803-hydroxyacyl-CoA dehydrogenase. (714 aa)
Bxe_C0295methylmalonyl-CoA epimerase. (186 aa)
Bxe_C03313-hydroxyacyl-CoA dehydrogenase. (269 aa)
Bxe_C0332Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
Bxe_C0352Conserved hypothetical protein. (386 aa)
vapC-2Nitrogen regulatory protein NtrR; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (134 aa)
Bxe_C0528NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit. (610 aa)
pgl-26-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (234 aa)
Bxe_C0574Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (265 aa)
Bxe_C0575Conserved hypothetical protein. (282 aa)
Bxe_C0581Conserved hypothetical protein; Citation: J. Bacteriol. 182:3784-3793(2000). (395 aa)
Bxe_C05963-hydroxyacyl-CoA dehydrogenase; Citation: J. Bacteriol. 186:3631-3639(2004). (300 aa)
Bxe_C0643Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)
Bxe_C0656Conserved hypothetical protein. (278 aa)
Bxe_C0679Putative plasmid stability protein. (145 aa)
Bxe_C0686Putative PIN (PilT N terminus) domain protein. (47 aa)
Bxe_C0702Putative acyl-CoA dehydrogenase. (384 aa)
Bxe_C0748Carbamate kinase; Belongs to the carbamate kinase family. (312 aa)
Bxe_C0763Conserved hypothetical protein. (148 aa)
Bxe_C0830Citrate lyase; Belongs to the HpcH/HpaI aldolase family. (282 aa)
Bxe_C0853Dihydrolipoamide dehydrogenase. (465 aa)
Bxe_C0854Dihydrolipoamide acyltransferase (E2) component of 2-oxoacid dehydrogenase complexes. (428 aa)
Bxe_C0858Putative dehydratase. (127 aa)
Bxe_C0860Putative thiolase. (384 aa)
Bxe_C08883-hydroxyacyl-CoA dehydrogenase; Phenylacetyl-CoA pathway; Citation: Proc. Natl. Acad. Sci. U.S.A. 95 (11), 6419-6424 (1998). J. Bacteriol. 182 (2), 286-294 (2000).Environ Microbiol. 2002 Dec;4(12):824-41. (522 aa)
Bxe_C0908Gluconolactonase. (342 aa)
Bxe_C0915Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Bxe_C0969Gluconolactonase. (304 aa)
Bxe_C0986Putative citrate synthase. (259 aa)
Bxe_C1008Citrate synthase. (429 aa)
Bxe_C10313-hydroxyacyl-CoA dehydrogenase. (508 aa)
Bxe_C1034Short chain enoyl-CoA hydratase. (256 aa)
Bxe_C10632-oxo-acid dehydrogenase E1 component homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (906 aa)
merAPutative mercuric ion reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (561 aa)
Bxe_C1233Transcriptional regulator, RpiR family. (280 aa)
Bxe_C1265Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa)
Bxe_C1324Conserved hypothetical protein. (224 aa)
Bxe_C1328Conserved hypothetical protein. (211 aa)
Bxe_C1329Conserved hypothetical protein. (205 aa)
Bxe_C1331Transcriptional regulator, RpiR family. (314 aa)
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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