STRINGSTRING
Bxe_A3166 Bxe_A3166 Bxe_C0740 Bxe_C0740 Bxe_C0462 Bxe_C0462 polA polA Bxe_B2797 Bxe_B2797 Bxe_B1450 Bxe_B1450 Bxe_B0474 Bxe_B0474 Bxe_B0424 Bxe_B0424 Bxe_B0256 Bxe_B0256 Bxe_B0154 Bxe_B0154 Bxe_A4461 Bxe_A4461 Bxe_A4318 Bxe_A4318 Bxe_A4106 Bxe_A4106 surA surA Bxe_A4005 Bxe_A4005 recG recG Bxe_A3637 Bxe_A3637 Bxe_A3292 Bxe_A3292 dnaE2 dnaE2 Bxe_A3082 Bxe_A3082 Bxe_A3008 Bxe_A3008 recC recC recB recB recD recD priA priA Bxe_A0227 Bxe_A0227 Bxe_A0578 Bxe_A0578 ruvB ruvB ruvA ruvA ruvC ruvC recA recA Bxe_A0844 Bxe_A0844 Bxe_A0914 Bxe_A0914 recO recO Bxe_A1174 Bxe_A1174 Bxe_A1224 Bxe_A1224 dnaQ dnaQ Bxe_A2643 Bxe_A2643 Bxe_A2479 Bxe_A2479 priB priB Bxe_A2361 Bxe_A2361 recR recR Bxe_A2291 Bxe_A2291 Bxe_A2280 Bxe_A2280 Bxe_A2262 Bxe_A2262 Bxe_A1895 Bxe_A1895 Bxe_A1768 Bxe_A1768 Bxe_A1564 Bxe_A1564
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Bxe_A3166Conserved hypothetical protein. (279 aa)
Bxe_C0740Hypothetical protein. (234 aa)
Bxe_C0462Putative DNA relaxase/nickase, TraS/VirD2-like. (349 aa)
polADNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (913 aa)
Bxe_B2797Putative transcriptional regulator. (339 aa)
Bxe_B1450Conserved hypothetical protein. (126 aa)
Bxe_B0474Putative peptidyl-prolyl isomerase. (250 aa)
Bxe_B0424Conserved hypothetical protein. (512 aa)
Bxe_B0256Hypothetical protein. (97 aa)
Bxe_B0154Putative PpiC-type peptidyl-prolyl cis-trans isomerase. (313 aa)
Bxe_A4461DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa)
Bxe_A4318Conserved hypothetical protein. (209 aa)
Bxe_A4106Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (177 aa)
surAPutative peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (453 aa)
Bxe_A4005Putative transcriptional regulator. (246 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (768 aa)
Bxe_A3637Putative DNA polymerase III chi subunit. (138 aa)
Bxe_A3292DNA polymerase III, alpha subunit. (1193 aa)
dnaE2DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1195 aa)
Bxe_A3082Hypothetical protein. (368 aa)
Bxe_A3008Hypothetical protein. (105 aa)
recCExodeoxyribonuclease V, RecC subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1133 aa)
recBExodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1230 aa)
recDExodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (704 aa)
priAPrimosomal protein n; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (747 aa)
Bxe_A0227Conserved hypothetical protein. (235 aa)
Bxe_A0578DNA polymerase III, delta subunit. (372 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (355 aa)
ruvADNA recombination protein, RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (193 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (180 aa)
recARecA DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (358 aa)
Bxe_A0844Hypothetical protein. (102 aa)
Bxe_A0914DNA polymerase III, epsilon subunit. (395 aa)
recODNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (306 aa)
Bxe_A1174Transcriptional regulator, AbrB family. (128 aa)
Bxe_A1224Putative single-stranded DNA binding protein. (146 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (244 aa)
Bxe_A2643Putative DNA relaxase/nickase, TraS/VirD2- like protein. (337 aa)
Bxe_A2479Putative cytoplasmic protein. (92 aa)
priBPutative primosomal replication protein N, PriB; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (99 aa)
Bxe_A2361DNA-directed DNA polymerase. (957 aa)
recRRecR protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa)
Bxe_A2291Putative PpiC-type peptidyl-prolyl cis- trans isomerase. (645 aa)
Bxe_A2280Putative peptidyl-prolyl cis-trans isomerase. (259 aa)
Bxe_A2262DNA polymerase III, delta prime subunit. (344 aa)
Bxe_A1895Conserved hypothetical protein. (336 aa)
Bxe_A1768Putative DNA relaxase/nickase, TraS/VirD2-like protein; Citation: Tauch,A., Schneiker,S.,Selbitschka,W., Microbiology (Reading, Engl.) 148 (PT 6),1637-1653 (2002). Schneiker,S., Keller,M., Droge,M.,Lanka,E.,Nucleic Acids Res. 29 (24), 5169-5181 (2001). (337 aa)
Bxe_A1564Exonuclease RecJ. (568 aa)
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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