STRINGSTRING
Meso_0437 Meso_0437 Meso_0438 Meso_0438 lpxK lpxK Meso_1315 Meso_1315 lpxD lpxD fabZ fabZ lpxA lpxA Meso_1392 Meso_1392 Meso_1393 Meso_1393 kdsA kdsA Meso_1757 Meso_1757 Meso_1758 Meso_1758 lpxC lpxC Meso_2737 Meso_2737 Meso_3668 Meso_3668 Meso_3669 Meso_3669 Meso_3670 Meso_3670 kdsB kdsB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Meso_0437PFAM: protein of unknown function DUF374; KEGG: mlo:mlr8268 hypothetical protein. (247 aa)
Meso_0438Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (439 aa)
lpxKlipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (343 aa)
Meso_1315PFAM: lipid A biosynthesis acyltransferase; KEGG: mlo:mlr1179 lipid A biosynthesis lauroyl acyltransferase. (306 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (365 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (156 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (277 aa)
Meso_1392PFAM: protein of unknown function DUF1009; KEGG: mlo:mll0631 hypothetical protein. (297 aa)
Meso_1393lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (392 aa)
kdsATIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase). (276 aa)
Meso_1757PFAM: permease YjgP/YjgQ; KEGG: mlo:mll7866 hypothetical protein. (416 aa)
Meso_1758PFAM: permease YjgP/YjgQ; KEGG: mlo:mll7865 hypothetical protein. (359 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (327 aa)
Meso_2737TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily. (331 aa)
Meso_3668PFAM: ABC transporter related; SMART: ATPase; KEGG: mlo:mll3197 ABC transporter ATP-binding protein (in RpoN upstream). (261 aa)
Meso_3669PFAM: OstA-like protein; KEGG: mlo:mll3198 hypothetical protein. (186 aa)
Meso_3670KEGG: mlo:mll3200 hypothetical protein. (235 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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