(5 nodes) Lipopolysaccharide biosynthesis, and Lipopolysaccharide biosynthesis network (Chelativorans sp. BNC1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Meso_0438	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (439 aa)
	lpxK	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (343 aa)
	kdsA	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase). (276 aa)
	Meso_2737	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily. (331 aa)
	kdsB	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)

Your Current Organism:

Chelativorans sp. BNC1

NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Meso_0438	Meso_2737	Meso_0438	Meso_2737	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily.	0.865
Meso_0438	kdsA	Meso_0438	Meso_1633	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase).	0.850
Meso_0438	kdsB	Meso_0438	Meso_4086	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	0.984
Meso_0438	lpxK	Meso_0438	Meso_0439	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.999
Meso_2737	Meso_0438	Meso_2737	Meso_0438	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily.	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	0.865
Meso_2737	kdsA	Meso_2737	Meso_1633	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily.	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase).	0.989
Meso_2737	kdsB	Meso_2737	Meso_4086	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily.	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	0.881
Meso_2737	lpxK	Meso_2737	Meso_0439	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily.	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.874
kdsA	Meso_0438	Meso_1633	Meso_0438	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase).	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	0.850
kdsA	Meso_2737	Meso_1633	Meso_2737	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase).	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily.	0.989
kdsA	kdsB	Meso_1633	Meso_4086	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase).	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	0.857
kdsA	lpxK	Meso_1633	Meso_0439	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase).	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.855
kdsB	Meso_0438	Meso_4086	Meso_0438	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	0.984
kdsB	Meso_2737	Meso_4086	Meso_2737	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily.	0.881
kdsB	kdsA	Meso_4086	Meso_1633	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase).	0.857
kdsB	lpxK	Meso_4086	Meso_0439	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.855
lpxK	Meso_0438	Meso_0439	Meso_0438	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	Three-deoxy-D-manno-octulosonic-acid transferase-like protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	0.999
lpxK	Meso_2737	Meso_0439	Meso_2737	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein sugar isomerase (SIS); KEGG: mlo:mll3023 hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily.	0.874
lpxK	kdsA	Meso_0439	Meso_1633	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase).	0.855
lpxK	kdsB	Meso_0439	Meso_4086	lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.	0.855