(12 nodes) Mixed, incl. Fumarate hydratase activity, and Malate dehydrogenase activity network (Chelativorans sp. BNC1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Meso_0056	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (502 aa)
	fumC	Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
	purU	Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (286 aa)
	Meso_1536	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). (770 aa)
	Meso_2427	TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin 4Fe-4S ferredoxin, iron-sulfur binding molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: bja:blr2317 formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (929 aa)
	Meso_2428	PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit. (557 aa)
	Meso_2449	TIGRFAM: Twin-arginine translocation pathway signal; PFAM: molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: mag:amb2671 anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (973 aa)
	Meso_2450	PFAM: 4Fe-4S ferredoxin, iron-sulfur binding; KEGG: bja:bll5476 formate dehydrogenase iron-sulfur subunit. (198 aa)
	Meso_2451	TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: bja:bll5475 putative formate dehydrogenase. (339 aa)
	mdh	Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (321 aa)
	Meso_3621	PFAM: fumarate lyase; KEGG: cme:CMD058C fumarate hydratase precursor. (470 aa)
	Meso_4030	PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr5329 NADP-dependent malic enzyme. (761 aa)

Your Current Organism:

Chelativorans sp. BNC1

NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Meso_0056	Meso_1536	Meso_0056	Meso_1536	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	0.963
Meso_0056	Meso_2427	Meso_0056	Meso_2427	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin 4Fe-4S ferredoxin, iron-sulfur binding molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: bja:blr2317 formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.805
Meso_0056	Meso_2428	Meso_0056	Meso_2428	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit.	0.836
Meso_0056	Meso_2449	Meso_0056	Meso_2449	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	TIGRFAM: Twin-arginine translocation pathway signal; PFAM: molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: mag:amb2671 anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.805
Meso_0056	Meso_2450	Meso_0056	Meso_2450	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	PFAM: 4Fe-4S ferredoxin, iron-sulfur binding; KEGG: bja:bll5476 formate dehydrogenase iron-sulfur subunit.	0.813
Meso_0056	Meso_2451	Meso_0056	Meso_2451	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: bja:bll5475 putative formate dehydrogenase.	0.800
Meso_0056	Meso_3621	Meso_0056	Meso_3621	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	PFAM: fumarate lyase; KEGG: cme:CMD058C fumarate hydratase precursor.	0.963
Meso_0056	Meso_4030	Meso_0056	Meso_4030	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr5329 NADP-dependent malic enzyme.	0.962
Meso_0056	fumC	Meso_0056	Meso_0355	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.963
Meso_0056	mdh	Meso_0056	Meso_3395	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	0.991
Meso_0056	purU	Meso_0056	Meso_0452	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).	0.803
Meso_1536	Meso_0056	Meso_1536	Meso_0056	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.963
Meso_1536	Meso_2427	Meso_1536	Meso_2427	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin 4Fe-4S ferredoxin, iron-sulfur binding molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: bja:blr2317 formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.843
Meso_1536	Meso_2428	Meso_1536	Meso_2428	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit.	0.907
Meso_1536	Meso_2449	Meso_1536	Meso_2449	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	TIGRFAM: Twin-arginine translocation pathway signal; PFAM: molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: mag:amb2671 anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.843
Meso_1536	Meso_2450	Meso_1536	Meso_2450	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	PFAM: 4Fe-4S ferredoxin, iron-sulfur binding; KEGG: bja:bll5476 formate dehydrogenase iron-sulfur subunit.	0.829
Meso_1536	Meso_2451	Meso_1536	Meso_2451	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: bja:bll5475 putative formate dehydrogenase.	0.823
Meso_1536	Meso_3621	Meso_1536	Meso_3621	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	PFAM: fumarate lyase; KEGG: cme:CMD058C fumarate hydratase precursor.	0.965
Meso_1536	Meso_4030	Meso_1536	Meso_4030	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr5329 NADP-dependent malic enzyme.	0.948
Meso_1536	fumC	Meso_1536	Meso_0355	Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating).	Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.965