STRINGSTRING
Meso_3880 Meso_3880 Meso_3655 Meso_3655 gpt gpt Meso_4052 Meso_4052 queF queF Meso_0474 Meso_0474 Meso_0494 Meso_0494 Meso_0580 Meso_0580 Meso_0907 Meso_0907 amn amn Meso_0923 Meso_0923 queG queG Meso_3093 Meso_3093 Meso_3073 Meso_3073 Meso_2403 Meso_2403 apt apt tgt tgt Meso_3656 Meso_3656 queA queA deoA deoA queC queC queE queE Meso_0059 Meso_0059 Meso_0150 Meso_0150
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Meso_3880TIGRFAM: putative thymidine phosphorylase; PFAM: glycosyl transferase, family 3 Pyrimidine nucleoside phosphorylase-like; KEGG: hch:HCH_01516 thymidine phosphorylase. (509 aa)
Meso_3655Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (131 aa)
gptPhosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (165 aa)
Meso_4052PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ret:RHE_CH03712 6-pyruvoyl tetrahydropterin synthase protein. (118 aa)
queFGTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (153 aa)
Meso_0474Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: mbo:Mb0380c probable carbon monoxyde dehydrogenase (large chain). (793 aa)
Meso_0494KEGG: mlo:mlr6947 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase. (221 aa)
Meso_0580Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: reu:Reut_B4507 aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead:aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. (704 aa)
Meso_0907Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: mlo:mlr7702 putative dehydrogenase. (770 aa)
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (499 aa)
Meso_0923PFAM: Appr-1-p processing; KEGG: mlo:mll7730 hypothetical protein. (174 aa)
queGDomain of unknown function DUF1730; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (383 aa)
Meso_3093TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mlo:mll3520 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa)
Meso_3073Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (208 aa)
Meso_2403Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (276 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (181 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (376 aa)
Meso_3656Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (268 aa)
queAQueuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (358 aa)
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (438 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (232 aa)
queEpreQ(0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (246 aa)
Meso_0059Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: mlo:mll1128 carbon-monoxide dehydrogenase large subunit. (781 aa)
Meso_0150Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (279 aa)
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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