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| | Meso_0715 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (318 aa) |
| | glyS | KEGG: mlo:mlr7435 glycyl-tRNA synthetase, beta chain. (789 aa) |
| | glyQ | PFAM: glycyl-tRNA synthetase, alpha subunit; KEGG: mlo:mlr7434 glycyl-tRNA synthetase alpha chain. (318 aa) |
| | rnhB | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (258 aa) |
| | pheT | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: mlo:mll5053 phenylalanine-tRNA ligase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (801 aa) |
| | pheS | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase, class IIc aminoacyl tRNA synthetase, class II-like; KEGG: mlo:mll5055 phenylalanyl-tRNA synthetase, alpha-subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (361 aa) |
| | rlmE | 23S rRNA Um-2552 2'-O-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (235 aa) |
| | Meso_0464 | PFAM: Fmu (Sun); KEGG: mlo:mlr6944 SUN-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (427 aa) |
| | Meso_0428 | TIGRFAM: Pseudouridine synthase, Rsu; PFAM: RNA-binding S4 pseudouridine synthase; KEGG: mlo:mlr8253 ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (466 aa) |
| | tadA | CMP/dCMP deaminase, zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (171 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (985 aa) |
| | hisS | TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S) Anticodon-binding; KEGG: bms:BRA0187 histidyl-tRNA synthetase. (503 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (311 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (247 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (120 aa) |
| | Meso_0372 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (248 aa) |
| | flbT | Flagellar FlbT; Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation. (145 aa) |
| | Meso_0146 | RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: atc:AGR_C_2739 ECF sigma factor. (167 aa) |
| | lysS | PFAM: Lysyl-tRNA synthetase, class 1c; KEGG: bhe:BH00240 lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (553 aa) |
| | Meso_3390 | MiaB-like tRNA modifying enzyme; KEGG: mlo:mlr4319 hypothetical protein; TIGRFAM: RNA modification enzyme, MiaB family MiaB-like tRNA modifying enzyme; PFAM: deoxyribonuclease/rho motif-related TRAM protein of unknown function UPF0004 Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (426 aa) |
| | Meso_3394 | PFAM: AFG1-like ATPase; KEGG: mlo:mll4310 hypothetical protein. (392 aa) |
| | Meso_3418 | PFAM: Fmu (Sun) NusB/RsmB/TIM44; KEGG: mlo:mlr4098 hypothetical protein, similarity to RNA-binding Sun protein, putative Fmu protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (460 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (212 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (417 aa) |
| | Meso_0429 | TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: mlo:mlr8254 hypothetical protein. (186 aa) |
| | trmD | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (235 aa) |
| | rlmH | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (173 aa) |
| | rsmG | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (210 aa) |
| | mnmG | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (622 aa) |
| | mnmE | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (442 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (429 aa) |
| | Meso_3578 | PFAM: aminoglycoside phosphotransferase protein of unknown function UPF0079; KEGG: mlo:mll5086 hypothetical protein. (498 aa) |
| | queG | Domain of unknown function DUF1730; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (383 aa) |
| | Meso_3667 | RNA polymerase, sigma 54 subunit, RpoN/SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (493 aa) |
| | Meso_3677 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (286 aa) |
| | Meso_3839 | PFAM: protein of unknown function DUF891; KEGG: xfa:XF1678 hypothetical protein. (123 aa) |
| | Meso_3863 | RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 Sigma-70, region 4 type 2; KEGG: dar:Daro_2950 sigma-70 region 2; Belongs to the sigma-70 factor family. (217 aa) |
| | Meso_3916 | PFAM: peptidase M22, glycoprotease; KEGG: mlo:mlr5530 hypothetical protein. (225 aa) |
| | miaB | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (475 aa) |
| | ybeY | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (163 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (232 aa) |
| | nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (534 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (133 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (312 aa) |
| | pnp | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (715 aa) |
| | rsmI | Protein of unknown function UPF0011; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (303 aa) |
| | rph | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (355 aa) |
| | Meso_4043 | TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase-like helicase-associated region DEAD/DEAH box helicase-like Helicase ATP-dependent-like; KEGG: mlo:mlr5306 ATP-dependent helicase. (821 aa) |
| | Meso_1784 | PFAM: protein of unknown function DUF1508; KEGG: ret:RHE_CH03509 hypothetical protein. (129 aa) |
| | Meso_1773 | PFAM: helicase-like DEAD/DEAH box helicase-like; KEGG: mlo:mll0224 probable ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (477 aa) |
| | Meso_1764 | TIGRFAM: conserved hypothetical protein; PFAM: YicC-like-like Domain of unknown function DUF1732; KEGG: mlo:mlr7856 hypothetical protein. (295 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (275 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (292 aa) |
| | rne | RNAse E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (868 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (336 aa) |
| | Meso_1648 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (327 aa) |
| | gltX2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (475 aa) |
| | Meso_1620 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (354 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (517 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (926 aa) |
| | dusA | tRNA-U16,U17-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (342 aa) |
| | gltX1 | glutamate--tRNA(Gln) ligase / glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (456 aa) |
| | Meso_1473 | RNA polymerase, sigma subunit, ECF family; PFAM: sigma-70 region 2 Tetratricopeptide TPR_2 Sigma-70, region 4 type 2; KEGG: mlo:mll2869 probable sigma-70 factor, ECF subfamily. (421 aa) |
| | rpoD | RNA polymerase, sigma 38 subunit, RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (668 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (639 aa) |
| | Meso_1447 | RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: rsp:RSP_2681 sigma factor, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa) |
| | Meso_1423 | PFAM: helicase-like DEAD/DEAH box helicase-like; KEGG: mlo:mlr0349 ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (460 aa) |
| | Meso_3380 | RNA polymerase, sigma 32 subunit, RpoH; PFAM: sigma-70 region 2 sigma-70 region 4; KEGG: mlo:mlr3862 RpoH-like sigma factor C. (284 aa) |
| | priA | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (726 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: mlo:mll4077 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (871 aa) |
| | tsaD | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (362 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (446 aa) |
| | rpoH | RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (308 aa) |
| | Meso_3146 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (343 aa) |
| | Meso_3107 | RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: mlo:mll3697 RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa) |
| | Meso_3067 | Transcriptional regulator, BolA protein family; PFAM: BolA-like protein; KEGG: mlo:mlr3565 putative BolA protein; Belongs to the BolA/IbaG family. (100 aa) |
| | Meso_3059 | PFAM: SirA-like; KEGG: mlo:msr3579 hypothetical protein; Belongs to the sulfur carrier protein TusA family. (76 aa) |
| | Meso_3026 | PFAM: glutamyl-tRNA synthetase, class Ic; KEGG: bmb:BruAb1_1635 tRNA synthetase, class I; Belongs to the class-I aminoacyl-tRNA synthetase family. (295 aa) |
| | Meso_2991 | CRISPR-associated protein, Cas2 family; KEGG: nwi:Nwi_1935 protein of unknown function DUF196; Belongs to the CRISPR-associated endoribonuclease Cas2 protein family. (87 aa) |
| | Meso_2956 | RNA polymerase, sigma 54 subunit, RpoN/SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (456 aa) |
| | rlmN | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (408 aa) |
| | Meso_2828 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: mlo:mll5129 hypothetical protein. (198 aa) |
| | vapC | PilT protein-like protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (135 aa) |
| | Meso_2697 | PFAM: Methyltransferase type 11 Methyltransferase type 12; KEGG: ret:RHE_PB00059 putative methyltransferase protein. (248 aa) |
| | Meso_2582 | KEGG: aci:ACIAD0603 hypothetical protein. (536 aa) |
| | Meso_2429 | PFAM: SirA-like; KEGG: nwi:Nwi_0975 SirA-like protein; Belongs to the sulfur carrier protein TusA family. (91 aa) |
| | Meso_2345 | KEGG: nwi:Nwi_2129 hypothetical protein. (345 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (391 aa) |
| | Meso_2208 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mlo:mlr2808 tRNA/rRNA methyltransferase. (266 aa) |
| | Meso_2176 | PFAM: Polynucleotide adenylyltransferase region; KEGG: mlo:mll2726 tRNA nucleotidyltransferase (CCA-adding enzyme); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (409 aa) |
| | trmL | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (153 aa) |
| | Meso_2147 | TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding region; KEGG: sme:SMc04456 putative chaperone protein. (115 aa) |
| | rsmH | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (339 aa) |
| | Meso_1972 | PFAM: ribonuclease T2; KEGG: bms:BR0703 ribonuclease T2 family protein; Belongs to the RNase T2 family. (216 aa) |
| | rlmJ | Protein of unknown function DUF519; Specifically methylates the adenine in position 2030 of 23S rRNA. (286 aa) |
| | nusG | Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (174 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1379 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1399 aa) |
| | argS | TIGRFAM: arginyl-tRNA synthetase; KEGG: bms:BR0877 arginyl-tRNA synthetase. (585 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (431 aa) |
| | trmFO | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (493 aa) |
| | tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (376 aa) |
| | Meso_1361 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (160 aa) |
| | rnr | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (765 aa) |
| | Meso_1276 | Transcriptional regulator, BolA protein family; PFAM: BolA-like protein; KEGG: mlo:msl0055 hypothetical protein; Belongs to the BolA/IbaG family. (77 aa) |
| | ttcA | PP-loop; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (284 aa) |
| | trmJ | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (262 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (909 aa) |
| | psuG | Indigoidine synthase A like protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (304 aa) |
| | Meso_1243 | RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: ret:RHE_PF00422 putative RNA polymerase sigma factor protein, ECF family. (244 aa) |
| | Meso_1204 | PFAM: DnaB-like helicase-like; KEGG: atc:AGR_C_2006 replicative DNA helicase. (481 aa) |
| | Meso_1150 | ATP-dependent DNA ligase LigD polymerase module; PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: atc:AGR_L_502 probable ATP-dependent DNA ligase PA2138. (845 aa) |
| | nusB | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (167 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (594 aa) |
| | rnd | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (392 aa) |
| | Meso_1084 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: bmb:BruAb1_1257 RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (276 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (442 aa) |
| | thrS | Ser-tRNA(Thr) hydrolase / threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (656 aa) |
| | Meso_0987 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (496 aa) |
| | cysS | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; KEGG: mlo:mlr7799 cysteine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (506 aa) |
| | rnc | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (238 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (131 aa) |
| | Meso_0944 | PFAM: protein of unknown function DUF88; KEGG: mlo:mll7752 hypothetical protein. (194 aa) |
| | rnhA | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (162 aa) |
| | Meso_0737 | 23S rRNA m(5)U-1939 methyltransferase; PFAM: deoxyribonuclease/rho motif-related TRAM (Uracil-5)-methyltransferase; KEGG: mlo:mlr7480 RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (413 aa) |
| | Meso_0736 | TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ RNA-binding S4; KEGG: bmb:BruAb1_0459 TlyA, hemolysin A. (252 aa) |
