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| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) |
| | Meso_0004 | PFAM: UBA/THIF-type NAD/FAD binding fold MoeZ/MoeB; KEGG: mlo:mll5577 molybdenum cofactor biosynthesis protein. (253 aa) |
| | lysS | PFAM: Lysyl-tRNA synthetase, class 1c; KEGG: bhe:BH00240 lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (553 aa) |
| | Meso_0032 | PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: mlo:mll5481 probable DNA ligase. (536 aa) |
| | Meso_0107 | KEGG: dvu:DVUA0119 type III secretion system ATPase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region H+-transporting two-sector ATPase, alpha/beta subunit-like; SMART: ATPase. (429 aa) |
| | Meso_0161 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. (475 aa) |
| | Meso_0168 | TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: mlo:mlr6539 acetoacetyl-CoA synthetase. (652 aa) |
| | Meso_0300 | ATPase, FliI/YscN family; KEGG: mlo:mlr2909 flagella-specific ATPase fliI; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; SMART: ATPase. (465 aa) |
| | Meso_0373 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (457 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (373 aa) |
| | hisS | TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S) Anticodon-binding; KEGG: bms:BRA0187 histidyl-tRNA synthetase. (503 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (985 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (519 aa) |
| | Meso_0651 | PFAM: O-antigen polymerase; KEGG: rsp:RSP_2549 putative polysaccharide polymerase. (428 aa) |
| | Meso_0662 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (440 aa) |
| | accD | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (307 aa) |
| | pheS | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase, class IIc aminoacyl tRNA synthetase, class II-like; KEGG: mlo:mll5055 phenylalanyl-tRNA synthetase, alpha-subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (361 aa) |
| | pheT | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: mlo:mll5053 phenylalanine-tRNA ligase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (801 aa) |
| | atpB | ATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (249 aa) |
| | atpE | ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa) |
| | atpF1 | H+-transporting two-sector ATPase, B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (193 aa) |
| | atpF2 | ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (159 aa) |
| | glyQ | PFAM: glycyl-tRNA synthetase, alpha subunit; KEGG: mlo:mlr7434 glycyl-tRNA synthetase alpha chain. (318 aa) |
| | glyS | KEGG: mlo:mlr7435 glycyl-tRNA synthetase, beta chain. (789 aa) |
| | purD | TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase protein of unknown function DUF201; KEGG: mlo:mlr7447 phosphoribosylamine-glycine ligase; Belongs to the GARS family. (426 aa) |
| | Meso_0918 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. (650 aa) |
| | Meso_0930 | PFAM: carboxyl transferase; KEGG: mlo:mll7731 3-methylcrotonyl-CoA carboxylase, beta subunit. (535 aa) |
| | Meso_0957 | PFAM: RimK-like ATP-grasp; KEGG: mlo:mlr7777 similar to ribosomal protein S6-glutamic acid ligase. (486 aa) |
| | cysS | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; KEGG: mlo:mlr7799 cysteine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (506 aa) |
| | thrS | Ser-tRNA(Thr) hydrolase / threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (656 aa) |
| | Meso_1020 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. (670 aa) |
| | Meso_1036 | TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase-like biotin/lipoate A/B protein ligase; KEGG: mlo:mll1351 biotin-protein ligase birA. (274 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (442 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (594 aa) |
| | Meso_1150 | ATP-dependent DNA ligase LigD polymerase module; PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: atc:AGR_L_502 probable ATP-dependent DNA ligase PA2138. (845 aa) |
| | Meso_1153 | KEGG: mlo:mll8434 hypothetical protein. (421 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (909 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (744 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (222 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa) |
| | purC | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; KEGG: mlo:mll0069 phosphoribosylaminoimidazole-succinocarboxamide synthase. (263 aa) |
| | Meso_1301 | KEGG: sme:SMc03959 hypothetical protein. (301 aa) |
| | gatC | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa) |
| | gatA | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (493 aa) |
| | Meso_1395 | KEGG: bja:blr1415 hypothetical glutathione S-transferase like protein. (208 aa) |
| | nadE | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (572 aa) |
| | gltX1 | glutamate--tRNA(Gln) ligase / glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (456 aa) |
| | Meso_1544 | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region glutamine synthetase, beta-Grasp; KEGG: sme:SMc00948 glutamine synthetase I protein. (469 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (926 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (517 aa) |
| | Meso_1586 | PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMa0150 malonyl-CoA synthase. (506 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | gltX2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (475 aa) |
| | Meso_1715 | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa) |
| | Meso_1716 | acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | gatB | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (499 aa) |
| | Meso_1735 | PFAM: carboxyl transferase; KEGG: mlo:mll0348 propionyl-CoA carboxylase. (510 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (434 aa) |
| | Meso_1784 | PFAM: protein of unknown function DUF1508; KEGG: ret:RHE_CH03509 hypothetical protein. (129 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (417 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (431 aa) |
| | argS | TIGRFAM: arginyl-tRNA synthetase; KEGG: bms:BR0877 arginyl-tRNA synthetase. (585 aa) |
| | Meso_1851 | PFAM: Hydantoinase/oxoprolinase Hydantoinaseoxoprolinase-like; KEGG: atc:AGR_L_3530 hypothetical protein. (518 aa) |
| | Meso_1870 | PFAM: glutamine synthetase, catalytic region; KEGG: sme:SMc01594 probable glutamine synthetase. (455 aa) |
| | purM | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein AIR synthase related protein-like; KEGG: mlo:mll7962 5'-phosphoribosyl-5-aminoimidazole synthetase. (368 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (703 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation. (308 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (465 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (467 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (477 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (483 aa) |
| | Meso_2082 | PFAM: GatB/Yqey; KEGG: sme:SMc01568 hypothetical protein. (149 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I Carbamoyl-phosphate synthase, small chain; KEGG: mlo:mlr2489 carbamoyl-phosphate synthetase small subunit; Belongs to the CarA family. (399 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain, oligomerisation Carbamoyl-phosphate synthetase large chain-like MGS-like; KEGG: mlo:mlr2517 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1162 aa) |
| | fhs | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: mlo:mlr2763 formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (559 aa) |
| | Meso_2296 | PFAM: Amidase; KEGG: dar:Daro_1360 amidase; Belongs to the amidase family. (456 aa) |
| | Meso_2379 | PFAM: Amidase; KEGG: sme:SMa1377 putative amidase; Belongs to the amidase family. (480 aa) |
| | Meso_2442 | KEGG: bja:bll5483 hypothetical protein. (248 aa) |
| | Meso_2468 | PFAM: GCN5-related N-acetyltransferase RimK-like ATP-grasp; KEGG: sme:SMb20482 hypothetical protein. (593 aa) |
| | Meso_2469 | TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II asparagine synthase; KEGG: sme:SMb20481 putative asparagine synthetase (glutamine amidotransferase) protein. (591 aa) |
| | Meso_2536 | PFAM: AMP-dependent synthetase and ligase; KEGG: mlo:mlr7293 acyl-CoA synthase. (558 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa) |
| | Meso_2646 | PFAM: Hydantoinase B/oxoprolinase; KEGG: atc:AGR_pTi_63 putative N-methylhydantoinase B. (647 aa) |
| | Meso_2647 | PFAM: Hydantoinase/oxoprolinase Hydantoinaseoxoprolinase-like; KEGG: atc:AGR_pTi_62 putative N-methylhydantoinase A. (678 aa) |
| | Meso_2700 | PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: mlo:mll9685 probable DNA ligase. (365 aa) |
| | Meso_2714 | PFAM: Amidase; KEGG: mlo:mlr2975 glutamyl-tRNA(Gln) amidotransferase, subunitA. (395 aa) |
| | Meso_2875 | PFAM: O-antigen polymerase; KEGG: sme:SMb21505 putative membrane protein, similar to Wzy-like polysaccharide polymerase ExoQ. (440 aa) |
| | nadE-2 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (330 aa) |
| | Meso_2882 | PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMb20650 putative long-chain fatty-acid-CoA ligase protein. (514 aa) |
| | Meso_2884 | TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II asparagine synthase; KEGG: sme:SMb20652 putative asparagine synthetase protein. (646 aa) |
| | Meso_2952 | PFAM: AMP-dependent synthetase and ligase; KEGG: ece:Z2730 hypothetical protein. (541 aa) |
| | Meso_3026 | PFAM: glutamyl-tRNA synthetase, class Ic; KEGG: bmb:BruAb1_1635 tRNA synthetase, class I; Belongs to the class-I aminoacyl-tRNA synthetase family. (295 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa) |
| | Meso_3071 | Cobaltochelatase CobT subunit; KEGG: mlo:mll3561 CobT protein; TIGRFAM: cobalt chelatase, pCobT subunit; PFAM: Cobalt chelatase, CobT subunit; SMART: von Willebrand factor, type A. (631 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (446 aa) |
| | Meso_3196 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: mlo:mll3954 hypothetical protein. (195 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: mlo:mll4077 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (871 aa) |
| | atpH | ATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (180 aa) |
| | atpA | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (509 aa) |
| | atpG | ATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (290 aa) |
| | atpD | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (519 aa) |
| | atpC | ATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | Meso_3329 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1158 aa) |
| | argG | PFAM: argininosuccinate synthase; KEGG: mlo:mlr4366 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (419 aa) |
| | Meso_3349 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (199 aa) |
| | Meso_3353 | PFAM: protein of unknown function UPF0005; KEGG: ret:RHE_CH03940 hypothetical protein; Belongs to the BI1 family. (248 aa) |
| | sucC | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa) |
| | sucD | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (303 aa) |
| | Meso_3402 | GumN; PFAM: GumN; KEGG: atc:AGR_C_4767 hypothetical protein. (346 aa) |
| | purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (364 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | Meso_3543 | PFAM: AMP-dependent synthetase and ligase; KEGG: pae:PA3860 acyl-CoA synthase. (660 aa) |
| | gshB | TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase-like glutathione synthetase, ATP-binding RimK-like ATP-grasp; KEGG: mlo:mll4735 glutathione synthetase; Belongs to the prokaryotic GSH synthase family. (316 aa) |
| | Meso_3639 | PFAM: AMP-dependent synthetase and ligase; KEGG: bbr:BB0583 crotonobetaine/carnitine-CoA ligase. (512 aa) |
| | Meso_3731 | PFAM: Hydantoinase/oxoprolinase Hydantoinaseoxoprolinase-like; KEGG: bld:BLi00395 putative N-methylhydantoinase A; RBL01743. (692 aa) |
| | Meso_4022 | PFAM: protein of unknown function DUF540; KEGG: mlo:mlr5338 similar to transport protein. (243 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (355 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (232 aa) |
| | Meso_4055 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (411 aa) |
