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aroK aroK aroB aroB Meso_3137 Meso_3137 Meso_3139 Meso_3139 Meso_3280 Meso_3280 Meso_3283 Meso_3283 Meso_3286 Meso_3286 Meso_3340 Meso_3340 asd asd dapF dapF Meso_3422 Meso_3422 aroE aroE dapB dapB aroA aroA Meso_3621 Meso_3621 Meso_3750 Meso_3750 Meso_3758 Meso_3758 Meso_3971 Meso_3971 Meso_3972 Meso_3972 Meso_4030 Meso_4030 fumC fumC dapE dapE Meso_0662 Meso_0662 aroC aroC dapA dapA Meso_1320 Meso_1320 Meso_1325 Meso_1325 Meso_1412 Meso_1412 Meso_1413 Meso_1413 Meso_1414 Meso_1414 Meso_1536 Meso_1536 Meso_1703 Meso_1703 aroQ aroQ Meso_1947 Meso_1947 Meso_2036 Meso_2036 Meso_2057 Meso_2057 Meso_2294 Meso_2294 Meso_2513 Meso_2513 Meso_2540 Meso_2540 Meso_2545 Meso_2545 nadA nadA Meso_2628 Meso_2628 Meso_2632 Meso_2632 hutU hutU Meso_2743 Meso_2743 Meso_2744 Meso_2744 Meso_2954 Meso_2954 Meso_2957 Meso_2957 Meso_2971 Meso_2971 Meso_2978 Meso_2978 hutU-2 hutU-2 hutH hutH hutI hutI Meso_3001 Meso_3001 lysA lysA dapD dapD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (195 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (375 aa)
Meso_3137PFAM: amidohydrolase Amidohydrolase 3; KEGG: bja:bll5494 hypothetical protein. (411 aa)
Meso_3139PFAM: dihydrodipicolinate synthetase; KEGG: rpa:RPA3190 possible dihydrodipicoline synthase related protein; Belongs to the DapA family. (308 aa)
Meso_3280PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: bja:blr2779 hypothetical protein; Belongs to the CoA-transferase III family. (396 aa)
Meso_3283PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: bbr:BB4746 hypothetical protein; Belongs to the CoA-transferase III family. (378 aa)
Meso_3286PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: bja:blr2779 hypothetical protein; Belongs to the CoA-transferase III family. (401 aa)
Meso_3340TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mlo:mlr4380 chorismate mutase. (108 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (293 aa)
Meso_3422PFAM: NAD-glutamate dehydrogenase; KEGG: mlo:mll4104 hypothetical protein. (1586 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (277 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (449 aa)
Meso_3621PFAM: fumarate lyase; KEGG: cme:CMD058C fumarate hydratase precursor. (470 aa)
Meso_3750PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: bbr:BB4884 putative dehydratase/racemase; Belongs to the CoA-transferase III family. (405 aa)
Meso_3758PFAM: dihydrodipicolinate synthetase; KEGG: jan:Jann_3748 dihydrodipicolinate synthetase; Belongs to the DapA family. (295 aa)
Meso_3971PFAM: dihydrodipicolinate synthetase; KEGG: bja:bll7953 hypothetical protein; Belongs to the DapA family. (309 aa)
Meso_3972PFAM: Shikimate/quinate 5-dehydrogenase Shikimate dehydrogenase substrate binding-like; KEGG: bme:BMEII0871 shikimate 5-dehydrogenase. (269 aa)
Meso_4030PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr5329 NADP-dependent malic enzyme. (761 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
dapESuccinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (395 aa)
Meso_0662TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (440 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa)
Meso_1320PFAM: phosphopantetheine-binding; KEGG: ret:RHE_CH02478 acyl carrier protein. (94 aa)
Meso_1325Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1204 aa)
Meso_1412Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (278 aa)
Meso_1413Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (119 aa)
Meso_1414TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: mlo:mll0786 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. (183 aa)
Meso_1536Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). (770 aa)
Meso_1703PFAM: protein of unknown function DUF339; KEGG: bmb:BruAb2_0644 hypothetical protein. (120 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa)
Meso_1947PFAM: dihydrodipicolinate synthetase; KEGG: atc:AGR_L_3338 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. (301 aa)
Meso_2036PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: mlo:mlr1614 hypothetical protein; Belongs to the CoA-transferase III family. (390 aa)
Meso_2057PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mlo:mll1646 glutamate synthase beta subunit. (450 aa)
Meso_2294PFAM: Shikimate/quinate 5-dehydrogenase Shikimate dehydrogenase substrate binding-like; KEGG: ppu:PP2608 shikimate dehydrogenase family protein. (288 aa)
Meso_25132,3-dimethylmalate lyase; KEGG: bbr:BB4108 carboxyvinyl-carboxyphosphonate phosphorylmutase. (293 aa)
Meso_2540PFAM: phenylalanine/histidine ammonia-lyase; KEGG: sth:STH3194 histidine ammonia-lyase. (514 aa)
Meso_2545TIGRFAM: urocanate hydratase; PFAM: Urocanase; KEGG: sth:STH3193 urocanase. (547 aa)
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (324 aa)
Meso_2628PFAM: phenylalanine/histidine ammonia-lyase; KEGG: ret:RHE_CH00352 histidine ammonia-lyase protein. (516 aa)
Meso_2632PFAM: phenylalanine/histidine ammonia-lyase; KEGG: sme:SMa0306 putative histidine ammonia-lyase. (535 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (554 aa)
Meso_2743TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mlo:mll3029 glutamate synthase (NADPH) small chain. (484 aa)
Meso_2744PFAM: glutamine amidotransferase, class-II glutamate synthase, alpha subunit-like ferredoxin-dependent glutamate synthase glutamate synthase; KEGG: mlo:mll3030 glutamate synthase (NADPH) large chain. (1574 aa)
Meso_2954PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: bbr:BB4678 CaiB/BaiF family protein; Belongs to the CoA-transferase III family. (408 aa)
Meso_2957PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: ade:Adeh_2342 alpha-methylacyl-CoA racemase; Belongs to the CoA-transferase III family. (364 aa)
Meso_2971PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: ppu:PP0159 CaiB/BaiF family protein; Belongs to the CoA-transferase III family. (419 aa)
Meso_2978PFAM: phenylalanine/histidine ammonia-lyase; KEGG: mlo:mll7124 histidine ammonia-lyase. (504 aa)
hutU-2Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (562 aa)
hutHTIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; KEGG: ret:RHE_PE00072 histidine ammonia-lyase protein; Belongs to the PAL/histidase family. (511 aa)
hutITIGRFAM: imidazolonepropionase; PFAM: amidohydrolase Amidohydrolase 3; KEGG: ret:RHE_PE00073 imidazolonepropionase protein; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (417 aa)
Meso_3001TIGRFAM: aspartate kinase aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase amino acid-binding ACT; KEGG: bmb:BruAb1_1850 aspartate kinase, monofunctional class; Belongs to the aspartokinase family. (424 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
dapDTIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: transferase hexapeptide repeat; KEGG: sme:SMc01732 probable 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase protein; Belongs to the transferase hexapeptide repeat family. (284 aa)
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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