STRINGSTRING
hisH hisH Meso_1599 Meso_1599 pyrG pyrG carA carA guaA guaA Meso_0143 Meso_0143 Meso_3767 Meso_3767 Meso_1501 Meso_1501 Meso_3197 Meso_3197 metAA metAA Meso_2944 Meso_2944 Meso_2816 Meso_2816 Meso_2409 Meso_2409 Meso_2199 Meso_2199 Meso_2182 Meso_2182 Meso_2181 Meso_2181 purQ purQ Meso_0622 Meso_0622 Meso_0590 Meso_0590 Meso_0573 Meso_0573 Meso_1484 Meso_1484
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
Meso_1599PFAM: helix-turn-helix, AraC type ThiJ/PfpI; KEGG: jan:Jann_3712 transcriptional regulator, AraC family. (361 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
carATIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I Carbamoyl-phosphate synthase, small chain; KEGG: mlo:mlr2489 carbamoyl-phosphate synthetase small subunit; Belongs to the CarA family. (399 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (519 aa)
Meso_0143PFAM: protein of unknown function DUF1037; KEGG: sme:SMb20329 probable ThuA protein, function. (261 aa)
Meso_3767PFAM: helix-turn-helix, AraC type ThiJ/PfpI; KEGG: rpb:RPB_1140 transcriptional regulator, AraC family. (371 aa)
Meso_1501PFAM: helix-turn-helix, AraC type ThiJ/PfpI; KEGG: jan:Jann_3712 transcriptional regulator, AraC family. (347 aa)
Meso_3197PFAM: glutamine amidotransferase class-I; KEGG: mlo:mll4216 glutamine amidotransferase. (261 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (312 aa)
Meso_2944PFAM: ThiJ/PfpI; KEGG: bbr:BB2338 probable transcriptional regulator. (378 aa)
Meso_2816Peptidase C26; PFAM: glutamine amidotransferase class-I peptidase C26; KEGG: mlo:mll5165 hypothetical protein. (255 aa)
Meso_2409Hypothetical protein. (690 aa)
Meso_2199TIGRFAM: glutamine amidotransferase of anthranilate synthase anthranilate synthase; PFAM: glutamine amidotransferase class-I Anthranilate synthase component I and chorismate binding protein Anthranilate synthase component I-like; KEGG: mlo:mlr2774 anthranilate synthase. (729 aa)
Meso_2182PFAM: protein of unknown function DUF1355; KEGG: mlo:mlr2735 hypothetical protein. (690 aa)
Meso_2181TIGRFAM: conserved hypothetical membrane protein; KEGG: mlo:mlr2734 hypothetical protein. (942 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (222 aa)
Meso_0622PFAM: helix-turn-helix, AraC type ThiJ/PfpI; KEGG: jan:Jann_3712 transcriptional regulator, AraC family. (340 aa)
Meso_0590Transcriptional regulator, AraC family with amidase-like domain; PFAM: helix-turn-helix, AraC type ThiJ/PfpI; KEGG: atc:AGR_L_1109 hypothetical protein. (347 aa)
Meso_0573PFAM: helix-turn-helix, AraC type ThiJ/PfpI; KEGG: bur:Bcep18194_A5985 transcriptional regulator, AraC family. (342 aa)
Meso_1484TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI; KEGG: bja:bll8044 proteinase. (186 aa)
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.