STRINGSTRING
Meso_0022 Meso_0022 Meso_0161 Meso_0161 Meso_0311 Meso_0311 Meso_0361 Meso_0361 Meso_0363 Meso_0363 Meso_0364 Meso_0364 purU purU Meso_0856 Meso_0856 Meso_0857 Meso_0857 gcvP gcvP gcvH gcvH Meso_1018 Meso_1018 Meso_1020 Meso_1020 Meso_1038 Meso_1038 glyA glyA gph gph Meso_1523 Meso_1523 Meso_1544 Meso_1544 Meso_1626 Meso_1626 Meso_1646 Meso_1646 Meso_1735 Meso_1735 Meso_1870 Meso_1870 Meso_1940 Meso_1940 Meso_2391 Meso_2391 Meso_2427 Meso_2427 Meso_2428 Meso_2428 Meso_2449 Meso_2449 Meso_2450 Meso_2450 Meso_2451 Meso_2451 Meso_2516 Meso_2516 Meso_2733 Meso_2733 Meso_2839 Meso_2839 Meso_2984 Meso_2984 Meso_3308 Meso_3308 Meso_3357 Meso_3357 Meso_3374 Meso_3374 Meso_3375 Meso_3375 mdh mdh Meso_3400 Meso_3400 acsA acsA Meso_3505 Meso_3505 glcB glcB Meso_3943 Meso_3943 Meso_4079 Meso_4079
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Meso_0022TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Meso_0161PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. (475 aa)
Meso_0311TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sme:SMc00768 isocitrate lyase. (429 aa)
Meso_0361PFAM: 4Fe-4S ferredoxin, iron-sulfur binding protein of unknown function DUF224, cysteine-rich region; KEGG: mlo:mlr6920 glycolate oxidase subunit, (Fe-S)protein. (443 aa)
Meso_0363PFAM: FAD linked oxidase-like; KEGG: mlo:mlr6919 glycolate oxidase subunits GlcE. (402 aa)
Meso_0364PFAM: FAD linked oxidase-like; KEGG: mlo:mlr6916 glycolate oxidase subunit GlcD. (498 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (286 aa)
Meso_0856TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. (714 aa)
Meso_0857PFAM: methylmalonyl-CoA mutase; KEGG: mlo:mll7621 methylmalonyl-CoA small subunit. (479 aa)
gcvPGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (931 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (122 aa)
Meso_1018TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: mlo:mlr0883 glycine cleavage system protein T. (364 aa)
Meso_1020Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. (670 aa)
Meso_1038methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ret:RHE_CH01621 putative lactoylglutathione lyase protein. (134 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (437 aa)
gphPhosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (231 aa)
Meso_1523TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: nwi:Nwi_2994 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (462 aa)
Meso_1544TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region glutamine synthetase, beta-Grasp; KEGG: sme:SMc00948 glutamine synthetase I protein. (469 aa)
Meso_1626TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase glucose-inhibited division protein A pyridine nucleotide-disulphide oxidoreductase dimerisation region FAD dependent oxidoreductase; KEGG: mlo:mlr0388 dihydrolipoamide dehydrogenase. (487 aa)
Meso_1646TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: mlo:mlr0629 citrate synthase; Belongs to the citrate synthase family. (429 aa)
Meso_1735PFAM: carboxyl transferase; KEGG: mlo:mll0348 propionyl-CoA carboxylase. (510 aa)
Meso_1870PFAM: glutamine synthetase, catalytic region; KEGG: sme:SMc01594 probable glutamine synthetase. (455 aa)
Meso_1940PFAM: MaoC-like dehydratase; KEGG: mag:amb0831 acyl dehydratase. (146 aa)
Meso_2391Citrate synthase; PFAM: regulatory protein, MerR Citrate synthase; KEGG: atc:AGR_pAT_441 hypothetical protein. (391 aa)
Meso_2427TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin 4Fe-4S ferredoxin, iron-sulfur binding molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: bja:blr2317 formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (929 aa)
Meso_2428PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit. (557 aa)
Meso_2449TIGRFAM: Twin-arginine translocation pathway signal; PFAM: molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: mag:amb2671 anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (973 aa)
Meso_2450PFAM: 4Fe-4S ferredoxin, iron-sulfur binding; KEGG: bja:bll5476 formate dehydrogenase iron-sulfur subunit. (198 aa)
Meso_2451TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: bja:bll5475 putative formate dehydrogenase. (339 aa)
Meso_2516PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: vpa:VPA1118 3-hydroxyisobutyrate dehydrogenase. (292 aa)
Meso_2733TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: mlo:mlr2994 2-keto-3-deoxy-6-phosphogluconate aldolase. (213 aa)
Meso_2839PFAM: MOFRL; KEGG: mlo:mlr5146 hypothetical hydroxypyruvate reductase protein. (421 aa)
Meso_2984PFAM: N-formylglutamate amidohydrolase; KEGG: ret:RHE_PE00071 formiminoglutamase protein. (266 aa)
Meso_3308Serine-glyoxylate aminotransferase apoenzyme; PFAM: aminotransferase, class V; KEGG: sil:SPOA0144 serine--glyoxylate transaminase, putative. (398 aa)
Meso_3357Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (923 aa)
Meso_3374TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr3847 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Meso_3375TIGRFAM: acetoacetyl-CoA reductase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_0747 short-chain dehydrogenase/reductase. (240 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (321 aa)
Meso_3400TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase glucose-inhibited division protein A fumarate reductase/succinate dehydrogenase flavoprotein-like pyridine nucleotide-disulphide oxidoreductase dimerisation region FAD dependent oxidoreductase; KEGG: mlo:mll4296 dihydrolipoamide dehydrogenase. (470 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
Meso_3505PFAM: Thiolase; KEGG: sme:SMc00262 putative 3-ketoacyl-CoA thiolase protein; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (732 aa)
Meso_3943PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mlo:mlr5574 2-hydroxyacid dehydrogenase. (333 aa)
Meso_4079PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mlo:mll5489 putative 2-hydroxyacid dehydrogenase. (318 aa)
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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