STRINGSTRING
queF queF Meso_0662 Meso_0662 Meso_0705 Meso_0705 ribB ribB folE folE Meso_1294 Meso_1294 Meso_1412 Meso_1412 Meso_1413 Meso_1413 Meso_1414 Meso_1414 moaA moaA moaC moaC Meso_1641 Meso_1641 Meso_1750 Meso_1750 Meso_1978 Meso_1978 Meso_2350 Meso_2350 Meso_2430 Meso_2430 mobA mobA Meso_2433 Meso_2433 Meso_2434 Meso_2434 Meso_2729 Meso_2729 Meso_3347 Meso_3347 queE queE Meso_4052 Meso_4052 queC queC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
queFGTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (153 aa)
Meso_0662TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (440 aa)
Meso_0705Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (180 aa)
ribBGTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (368 aa)
folEPFAM: GTP cyclohydrolase I; KEGG: mlo:mlr0922 GTP cyclohydrolase I. (222 aa)
Meso_1294Molybdenum cofactor cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: mlo:mlr0093 hypothetical protein. (538 aa)
Meso_1412Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (278 aa)
Meso_1413Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (119 aa)
Meso_1414TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: mlo:mll0786 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. (183 aa)
moaAGTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (334 aa)
moaCGTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (172 aa)
Meso_1641Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (401 aa)
Meso_1750Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa)
Meso_1978PFAM: molybdopterin biosynthesis MoaE; KEGG: mlo:mlr7915 molybdopterin converting factor, subunit 2. (154 aa)
Meso_2350TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; KEGG: afu:AF2089 hypothetical protein. (327 aa)
Meso_2430Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (418 aa)
mobAMolybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (208 aa)
Meso_2433Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (649 aa)
Meso_2434Molybdopterin binding domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (375 aa)
Meso_2729TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: bmb:BruAb2_0080 para-aminobenzoate synthase, component I. (385 aa)
Meso_3347PFAM: transcriptional coactivator/pterin dehydratase; KEGG: mlo:mlr4350 pterin-4a-carbinolamine dehydratase. (98 aa)
queEpreQ(0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (246 aa)
Meso_4052PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ret:RHE_CH03712 6-pyruvoyl tetrahydropterin synthase protein. (118 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (232 aa)
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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