Your Input: | |
| | Meso_0005 | PFAM: ribulose-phosphate 3-epimerase; KEGG: mlo:mlr4760 pentose(ribulose)-5-phosphate-3-epimerase. (223 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase, class I and II aminotransferase class-III; KEGG: mlo:mlr5646 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa) |
| | Meso_0021 | PFAM: Enoyl-CoA hydratase/isomerase 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding NAD-dependent glycerol-3-phosphate dehydrogenase-like; KEGG: mlo:mlr5629 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase. (740 aa) |
| | Meso_0022 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | Meso_0052 | 3-hydroxybenzoate 6-hydroxylase; PFAM: monooxygenase, FAD-binding FAD dependent oxidoreductase; KEGG: bur:Bcep18194_B1886 monooxygenase, FAD-binding. (413 aa) |
| | Meso_0053 | TIGRFAM: gentisate 1,2-dioxygenase; PFAM: Cupin 2, conserved barrel; KEGG: pae:PA2470 gentisate 1,2-dioxygenase. (353 aa) |
| | Meso_0054 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: bte:BTH_II1389 fumarylacetoacetate hydrolase family protein. (232 aa) |
| | Meso_0055 | TIGRFAM: maleylacetoacetate isomerase; PFAM: glutathione S-transferase-like; KEGG: bbr:BB3255 putative glutathione-S-transferase. (214 aa) |
| | Meso_0056 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (502 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: sme:SMc02163 probable glucose-6-phosphate isomerase protein. (545 aa) |
| | Meso_0079 | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: rsp:RSP_3399 carbon-nitrogen hydrolase family protein. (272 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa) |
| | edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (604 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (242 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa) |
| | Meso_0161 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. (475 aa) |
| | Meso_0311 | TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sme:SMc00768 isocitrate lyase. (429 aa) |
| | Meso_0313 | PFAM: aldehyde dehydrogenase; KEGG: atc:AGR_L_75 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (792 aa) |
| | Meso_0316 | TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: mlo:mll1676 gluconokinase. (174 aa) |
| | Meso_0332 | PFAM: Asp/Glu racemase; KEGG: bur:Bcep18194_A5279 Asp/Glu racemase. (238 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | Meso_0361 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding protein of unknown function DUF224, cysteine-rich region; KEGG: mlo:mlr6920 glycolate oxidase subunit, (Fe-S)protein. (443 aa) |
| | Meso_0363 | PFAM: FAD linked oxidase-like; KEGG: mlo:mlr6919 glycolate oxidase subunits GlcE. (402 aa) |
| | Meso_0364 | PFAM: FAD linked oxidase-like; KEGG: mlo:mlr6916 glycolate oxidase subunit GlcD. (498 aa) |
| | dapD | TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: transferase hexapeptide repeat; KEGG: sme:SMc01732 probable 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase protein; Belongs to the transferase hexapeptide repeat family. (284 aa) |
| | dapE | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (395 aa) |
| | Meso_0405 | PFAM: Rhodanese-like; KEGG: rpa:RPA3613 putative thiosulfate sulfurtransferase. (284 aa) |
| | Meso_0411 | PFAM: NAD-dependent epimerase/dehydratase short-chain dehydrogenase/reductase SDR 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: bja:bll6359 putative oxidoreductase protein. (247 aa) |
| | Meso_0446 | TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold Ndr; KEGG: sme:SMb20579 putative beta-ketoadipate enol-lactone hydrolase protein. (264 aa) |
| | Meso_0451 | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (336 aa) |
| | Meso_0455 | 5-deoxyglucuronate isomerase; PFAM: Myo-inositol catabolism IolB region; KEGG: atc:AGR_L_719 putative myo-inositol catabolism protein. (271 aa) |
| | Meso_0580 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: reu:Reut_B4507 aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead:aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding. (704 aa) |
| | Meso_0581 | PFAM: molybdopterin dehydrogenase, FAD-binding; KEGG: bja:blr2218 putative xanthine dehydrogenase. (329 aa) |
| | Meso_0582 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: ferredoxin [2Fe-2S]-binding; KEGG: mlo:mlr1925 oxidoreductase, iron-sulphur binding subunit. (199 aa) |
| | accD | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (307 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (209 aa) |
| | thrB | TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; KEGG: mlo:mlr7503 homoserine kinase; Belongs to the pseudomonas-type ThrB family. (322 aa) |
| | Meso_0760 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase. (467 aa) |
| | Meso_0764 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: atc:AGR_C_1458 conserved hypothetical protein VC1645. (203 aa) |
| | Meso_0772 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme pyruvate phosphate dikinase, PEP/pyruvate-binding PEP-utilising enzyme, mobile region; KEGG: mlo:mlr7532 pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (887 aa) |
| | Meso_0784 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mlo:mll5243 3-oxoacyl-(acyl carrier protein) reductase. (246 aa) |
| | Meso_0802 | KEGG: bbr:BB3568 putative decarboxylase. (170 aa) |
| | Meso_0803 | PFAM: thiamine pyrophosphate enzyme-like TPP-binding; KEGG: bbr:BB3569 hypothetical protein. (189 aa) |
| | Meso_0804 | PFAM: aldehyde dehydrogenase; KEGG: pfo:Pfl_3233 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (500 aa) |
| | Meso_0805 | PFAM: Carboxymuconolactone decarboxylase; KEGG: bur:Bcep18194_B1956 hypothetical protein. (188 aa) |
| | Meso_0812 | KEGG: bpa:BPP0387 4,5-dihydroxyphthalate decarboxylase. (336 aa) |
| | Meso_0813 | PFAM: monooxygenase, FAD-binding FAD dependent oxidoreductase; KEGG: reu:Reut_B3601 salicylate 1-monooxygenase. (377 aa) |
| | Meso_0831 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pca:Pcar_1779 phosphomannomutase. (451 aa) |
| | cysD | TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: mlo:mlr7575 sulfate adenylyltransferase subunit 2. (301 aa) |
| | cysN | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (640 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (274 aa) |
| | Meso_0856 | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. (714 aa) |
| | Meso_0857 | PFAM: methylmalonyl-CoA mutase; KEGG: mlo:mll7621 methylmalonyl-CoA small subunit. (479 aa) |
| | Meso_0860 | TIGRFAM: haloacid dehalogenase, type II HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase-like hydrolase; KEGG: mlo:mll7634 2-haloacid halidohydrolase Iva. (220 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa) |
| | Meso_0989 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX; KEGG: bmb:BruAb1_1274 GlpX protein. (328 aa) |
| | Meso_1020 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. (670 aa) |
| | Meso_1038 | methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ret:RHE_CH01621 putative lactoylglutathione lyase protein. (134 aa) |
| | Meso_1051 | KEGG: bja:bll6809 hypothetical protein. (175 aa) |
| | Meso_1053 | Succinate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: atc:AGR_L_2660 hypothetical protein. (478 aa) |
| | Meso_1063 | Demethylmenaquinone methyltransferase-like protein; KEGG: mka:MK1449 demethylmenaquinone methyltransferase. (254 aa) |
| | Meso_1068 | KEGG: bja:bll3172 putative sulfopyruvate decarboxylase subunit alpha. (182 aa) |
| | Meso_1069 | PFAM: thiamine pyrophosphate enzyme-like TPP-binding; KEGG: bja:bll3171 hypothetical protein. (199 aa) |
| | Meso_1074 | PFAM: Mandelate racemase/muconate lactonizing enzyme-like; KEGG: bja:blr6118 hypothetical protein. (394 aa) |
| | Meso_1076 | PFAM: Hydratase/decarboxylase; KEGG: reu:Reut_B5691 4-oxalocrotonate decarboxylase. (260 aa) |
| | Meso_1117 | PFAM: monooxygenase, FAD-binding FAD dependent oxidoreductase; KEGG: mlo:mll8158 salicylate hydroxylase. (399 aa) |
| | Meso_1129 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mlo:mll8390 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (343 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (437 aa) |
| | Meso_1267 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: bmb:BruAb1_1204 isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa) |
| | Meso_1284 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mlo:mlr0078 hypothetical protein. (267 aa) |
| | Meso_1317 | PFAM: Alcohol dehydrogenase, zinc-binding Alcohol dehydrogenase GroES-like; KEGG: mlo:mlr1178 alcohol dehydrogenase. (342 aa) |
| | Meso_1323 | TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: mlo:mll1168 succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa) |
| | Meso_1424 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mlr0353 O-acetylserine (thiol) lyase. (346 aa) |
| | Meso_1426 | PFAM: Rhodanese-like; KEGG: mlo:mlr0355 thiosulfate sulfurtransferase. (281 aa) |
| | Meso_1451 | TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like nitrite and sulphite reductase 4Fe-4S region BFD-like [2Fe-2S]-binding region; KEGG: nwi:Nwi_0719 BFD-like (2Fe-2S)-binding region. (814 aa) |
| | Meso_1452 | TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] region; KEGG: mlo:mlr2863 nitrite reductase small subunit. (112 aa) |
| | Meso_1453 | Assimilatory nitrate reductase (NADH) alpha subunit apoprotein; PFAM: molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region BFD-like [2Fe-2S]-binding region; KEGG: mlo:mlr2864 nitrate reductase large subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (942 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (235 aa) |
| | Meso_1523 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: nwi:Nwi_2994 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (462 aa) |
| | Meso_1524 | PFAM: Enoyl-CoA hydratase/isomerase 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: nwi:Nwi_2993 3-hydroxyacyl-CoA dehydrogenase NAD-binding. (706 aa) |
| | gltX1 | glutamate--tRNA(Gln) ligase / glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (456 aa) |
| | Meso_1536 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). (770 aa) |
| | Meso_1544 | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region glutamine synthetase, beta-Grasp; KEGG: sme:SMc00948 glutamine synthetase I protein. (469 aa) |
| | Meso_1609 | PFAM: aldo/keto reductase; KEGG: bja:blr1124 oxidoreductase. (334 aa) |
| | Meso_1610 | PFAM: amidohydrolase 2; KEGG: bja:blr1125 hypothetical protein. (288 aa) |
| | Meso_1626 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase glucose-inhibited division protein A pyridine nucleotide-disulphide oxidoreductase dimerisation region FAD dependent oxidoreductase; KEGG: mlo:mlr0388 dihydrolipoamide dehydrogenase. (487 aa) |
| | Meso_1628 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (452 aa) |
| | Meso_1629 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (466 aa) |
| | pdhA | Dehydrogenase, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (360 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa) |
| | gltX2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (475 aa) |
| | Meso_1646 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: mlo:mlr0629 citrate synthase; Belongs to the citrate synthase family. (429 aa) |
| | Meso_1715 | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa) |
| | Meso_1716 | acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | Meso_1729 | TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat serine acetyltransferase-like; KEGG: mlo:mlr0175 serine acetyltransferase. (272 aa) |
| | Meso_1735 | PFAM: carboxyl transferase; KEGG: mlo:mll0348 propionyl-CoA carboxylase. (510 aa) |
| | Meso_1744 | TIGRFAM: phosphoserine phosphatase SerB HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase-like hydrolase; KEGG: mlo:mlr1449 probable phosphoserine phosphatase. (295 aa) |
| | Meso_1868 | PFAM: iron-containing alcohol dehydrogenase; KEGG: sme:SMc01582 putative alcohol dehydrogenase protein. (381 aa) |
| | Meso_1870 | PFAM: glutamine synthetase, catalytic region; KEGG: sme:SMc01594 probable glutamine synthetase. (455 aa) |
| | Meso_1906 | (2Fe-2S)-binding protein; PFAM: ferredoxin [2Fe-2S]-binding; KEGG: sme:SMb20403 putative oxidoreductase subunit protein. (164 aa) |
| | Meso_1907 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: sme:SMb20404 putative aldehyde dehydrogenase protein. (749 aa) |
| | Meso_1922 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. (436 aa) |
| | Meso_1934 | PFAM: CoA-binding; KEGG: eba:ebA5611 organic acid-CoA ligase (ADP forming),similar to feruloyl-CoA synthetase. (684 aa) |
| | Meso_1940 | PFAM: MaoC-like dehydratase; KEGG: mag:amb0831 acyl dehydratase. (146 aa) |
| | Meso_1987 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: dienelactone hydrolase; KEGG: sme:SMc00817 putative carboxymethylenebutenolidase (dienelactone hydrolase) protein. (291 aa) |
| | Meso_2028 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: mlo:mll1587 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (305 aa) |
| | Meso_2049 | TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase; KEGG: sme:SMb20578 putative gamma carboxymuconolactone decarboxylase protein. (133 aa) |
| | Meso_2050 | TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: sme:SMb20577 protocatechuate 3,4-dioxygenase, beta subunit. (246 aa) |
| | Meso_2051 | TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: bmb:BruAb2_0580 protocatechuate 3,4-dioxygenase, alpha subunit. (204 aa) |
| | Meso_2052 | TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase; KEGG: mlo:mlr7211 3-carboxy-cis,cis-muconate cycloisomerase. (354 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | fhs | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: mlo:mlr2763 formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (559 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (390 aa) |
| | Meso_2236 | PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: nwi:Nwi_1947 putative phosphoketolase. (800 aa) |
| | Meso_2239 | TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; KEGG: hch:HCH_05488 carbamate kinase; Belongs to the carbamate kinase family. (305 aa) |
| | Meso_2243 | TIGRFAM: nitrite reductase, copper-containing; PFAM: multicopper oxidase, type 1 multicopper oxidase, type 2 multicopper oxidase, type 3; KEGG: rpa:RPA4145 dissimilatory nitrite reductase. (367 aa) |
| | Meso_2263 | PFAM: Alcohol dehydrogenase, zinc-binding Alcohol dehydrogenase GroES-like; KEGG: bms:BR1061 alcohol dehydrogenase, zinc-containing. (328 aa) |
| | Meso_2296 | PFAM: Amidase; KEGG: dar:Daro_1360 amidase; Belongs to the amidase family. (456 aa) |
| | Meso_2391 | Citrate synthase; PFAM: regulatory protein, MerR Citrate synthase; KEGG: atc:AGR_pAT_441 hypothetical protein. (391 aa) |
| | Meso_2396 | PFAM: Mandelate racemase/muconate lactonizing enzyme-like; KEGG: cgb:cg2635 chloromuconate cycloisomerase. (386 aa) |
| | Meso_2416 | PFAM: aminotransferase class-III; KEGG: mlo:mll7127 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa) |
| | Meso_2417 | PFAM: aldehyde dehydrogenase; KEGG: mlo:mll7128 succinic semialdehyde dehydrogenase. (525 aa) |
| | Meso_2427 | TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin 4Fe-4S ferredoxin, iron-sulfur binding molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: bja:blr2317 formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (929 aa) |
| | Meso_2428 | PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit. (557 aa) |
| | Meso_2449 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: molybdopterin oxidoreductase molydopterin dinucleotide-binding region molybdopterin oxidoreductase Fe4S4 region; KEGG: mag:amb2671 anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (973 aa) |
| | Meso_2450 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding; KEGG: bja:bll5476 formate dehydrogenase iron-sulfur subunit. (198 aa) |
| | Meso_2451 | TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: bja:bll5475 putative formate dehydrogenase. (339 aa) |
| | hmgA | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (452 aa) |
| | Meso_2465 | PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: pae:PA4091 4-hydroxyphenylacetate 3-monooxygenase large chain. (520 aa) |
| | Meso_2481 | PFAM: acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like; KEGG: bms:BR1085 glutaryl-CoA dehydrogenase. (406 aa) |
| | Meso_2492 | PFAM: Cupin 2, conserved barrel; KEGG: pfl:PFL_3363 2,4'-dihydroxyacetophenone dioxygenase. (177 aa) |
| | Meso_2503 | PFAM: HpcH/HpaI aldolase; KEGG: bmb:BruAb2_1093 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, hypothetical. (252 aa) |
| | Meso_2504 | TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase; KEGG: jan:Jann_3499 2-oxo-hepta-3-ene-1,7-dioic acid hydratase. (266 aa) |
| | Meso_2506 | TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bme:BMEII0136 homoprotocatechuate 2,3-dioxygenase. (326 aa) |
| | Meso_2507 | TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: bms:BRA1161 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (503 aa) |
| | Meso_2508 | PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: bms:BRA1162 5-carboxymethyl-2-hydroxymuconate delta isomerase. (127 aa) |
| | Meso_2515 | TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: sme:SMb20371 putative sugar-phosphate isomerase protein. (148 aa) |
| | Meso_2527 | PFAM: Carboxymuconolactone decarboxylase; KEGG: ret:RHE_PF00193 gamma-carboxymuconolactone decarboxylase protein. (132 aa) |
| | Meso_2544 | PFAM: amidohydrolase; KEGG: ret:RHE_CH00351 probable allantoinase protein. (459 aa) |
| | Meso_2573 | TIGRFAM: 4-hydroxybenzoate 3-monooxygenase; PFAM: monooxygenase, FAD-binding; KEGG: reu:Reut_B5020 aromatic-ring hydroxylase. (389 aa) |
| | Meso_2605 | PFAM: Pyrrolo-quinoline quinone; KEGG: bja:bll6220 putative alcohol dehydrogenase precursor. (563 aa) |
| | Meso_2606 | SMART: Pyrrolo-quinoline quinone; KEGG: pfl:PFL_2221 quinoprotein ethanol dehydrogenase. (558 aa) |
| | Meso_2641 | PFAM: amidohydrolase; KEGG: ret:RHE_CH00351 probable allantoinase protein. (452 aa) |
| | Meso_2642 | PFAM: Rhodanese-like; KEGG: mag:amb1299 rhodanese-related sulfurtransferase. (286 aa) |
| | Meso_2652 | PFAM: aldehyde dehydrogenase; KEGG: cgb:cg0067 succinate-semialdehyde dehydrogenase (NADP+). (500 aa) |
| | Meso_2671 | PFAM: Alcohol dehydrogenase, zinc-binding Alcohol dehydrogenase GroES-like; KEGG: sme:SMb20170 probable glutathione-dependent formaldehyde dehydrogenase protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa) |
| | ureA | TIGRFAM: urease, gamma subunit; PFAM: Urease, gamma subunit region; KEGG: sme:SMc01941 urease gamma subunit protein; Belongs to the urease gamma subunit family. (100 aa) |
| | ureB | TIGRFAM: urease, beta subunit; PFAM: Urease, beta subunit; KEGG: jan:Jann_1747 urease, beta subunit; Belongs to the urease beta subunit family. (101 aa) |
| | ureC | Urease. Metallo peptidase. MEROPS family M38; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase Urease alpha-subunit-like; KEGG: mlo:mll4940 urease alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (570 aa) |
| | Meso_2714 | PFAM: Amidase; KEGG: mlo:mlr2975 glutamyl-tRNA(Gln) amidotransferase, subunitA. (395 aa) |
| | Meso_2733 | TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: mlo:mlr2994 2-keto-3-deoxy-6-phosphogluconate aldolase. (213 aa) |
| | Meso_2743 | TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mlo:mll3029 glutamate synthase (NADPH) small chain. (484 aa) |
| | Meso_2744 | PFAM: glutamine amidotransferase, class-II glutamate synthase, alpha subunit-like ferredoxin-dependent glutamate synthase glutamate synthase; KEGG: mlo:mll3030 glutamate synthase (NADPH) large chain. (1574 aa) |
| | Meso_2745 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (352 aa) |
| | Meso_2823 | PFAM: coenzyme A transferase; KEGG: mlo:mll4183 acetate CoA-transferase, alpha subunit. (285 aa) |
| | Meso_2824 | PFAM: coenzyme A transferase; KEGG: mlo:mll4181 acetoacetyl-CoA transferase b subunit. (256 aa) |
| | Meso_2825 | 3-oxoadipyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferases beta-ketoadipyl CoA thiolase; PFAM: Thiolase; KEGG: mlo:mll4180 beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | Meso_2830 | PFAM: protein of unknown function DUF861, cupin_3 Cupin 2, conserved barrel; KEGG: mlo:mll5131 hypothetical protein. (280 aa) |
| | Meso_2832 | PFAM: Transthyretin; KEGG: mlo:mlr5133 hypothetical protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (121 aa) |
| | Meso_2833 | PFAM: ferredoxin molybdopterin dehydrogenase, FAD-binding [2Fe-2S]-binding CO dehydrogenase flavoprotein-like; KEGG: mlo:mlr5134 xanthine dehydrogenase, xdhA. (492 aa) |
| | Meso_2834 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: mlo:mlr5135 xanthine dehydrogenase, xdhB. (781 aa) |
| | Meso_2839 | PFAM: MOFRL; KEGG: mlo:mlr5146 hypothetical hydroxypyruvate reductase protein. (421 aa) |
| | Meso_2887 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: mlo:mlr8306 hypothetical protein. (338 aa) |
| | Meso_2890 | SMART: Pyrrolo-quinoline quinone; KEGG: bja:blr6207 probable quinoprotein ethanol dehydrogenase precursor. (583 aa) |
| | Meso_2891 | PFAM: cytochrome c, class I. (201 aa) |
| | Meso_2920 | DoxX; PFAM: DoxX; KEGG: sco:SCO0201 integral membrane protein SCJ1213c. (160 aa) |
| | Meso_2926 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: eba:p2A120 UbiD-like subunit of potential (de) carboxylase; Belongs to the UbiD family. (483 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (197 aa) |
| | Meso_2941 | PFAM: aldo/keto reductase; KEGG: ret:RHE_CH00449 probable oxidoreductase protein. (284 aa) |
| | Meso_2946 | PFAM: 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: ppu:PP3282 3-hydroxyacyl-CoA dehydrogenase PaaC. (485 aa) |
| | Meso_2948 | PFAM: 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: sth:STH214 3-hydroxyacyl-CoA dehydrogenase. (506 aa) |
| | Meso_2960 | PFAM: Carboxymuconolactone decarboxylase; KEGG: bbr:BB4071 4-carboxymuconolactone decarboxylase. (126 aa) |
| | Meso_2969 | KEGG: gme:Gmet_2205 coenzyme A transferase. (300 aa) |
| | Meso_2970 | PFAM: coenzyme A transferase; KEGG: nph:NP6032A 3-oxoacid CoA-transferase, beta subunit. (256 aa) |
| | Meso_3001 | TIGRFAM: aspartate kinase aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase amino acid-binding ACT; KEGG: bmb:BruAb1_1850 aspartate kinase, monofunctional class; Belongs to the aspartokinase family. (424 aa) |
| | Meso_3035 | PFAM: 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: mlo:mlr3490 3-hydroxybutyryl-CoA dehydrogenase. (293 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | Meso_3045 | PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: mag:amb4454 L-lactate dehydrogenase and related alpha-hydroxy acid dehydrogenase. (374 aa) |
| | Meso_3046 | PFAM: Mandelate racemase/muconate lactonizing enzyme-like; KEGG: ret:RHE_PF00381 putative mandelate racemase protein. (386 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa) |
| | Meso_3139 | PFAM: dihydrodipicolinate synthetase; KEGG: rpa:RPA3190 possible dihydrodipicoline synthase related protein; Belongs to the DapA family. (308 aa) |
| | Meso_3152 | PFAM: Cupin 2, conserved barrel; KEGG: pst:PSPTO3051 2,4'-dihydroxyacetophenone dioxygenase. (175 aa) |
| | Meso_3161 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mlo:mll3875 phosphoglycerate dehydrogenase. (532 aa) |
| | Meso_3162 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (390 aa) |
| | Meso_3201 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (232 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | Meso_3243 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa) |
| | Meso_3244 | TIGRFAM: succinate dehydrogenase, flavoprotein subunit succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: bme:BMEI0161 succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (611 aa) |
| | Meso_3245 | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: bms:BR1903 succinate dehydrogenase, hydrophobic membrane anchor protein, putative. (127 aa) |
| | Meso_3246 | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mlo:mll4266 succinate dehydrogenase membrane anchor subunit. (134 aa) |
| | Meso_3256 | PFAM: pyruvate kinase; KEGG: mlo:mll3819 pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa) |
| | Meso_3308 | Serine-glyoxylate aminotransferase apoenzyme; PFAM: aminotransferase, class V; KEGG: sil:SPOA0144 serine--glyoxylate transaminase, putative. (398 aa) |
| | Meso_3329 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1158 aa) |
| | Meso_3357 | Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (923 aa) |
| | Meso_3374 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr3847 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | Meso_3375 | TIGRFAM: acetoacetyl-CoA reductase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_0747 short-chain dehydrogenase/reductase. (240 aa) |
| | asd | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (293 aa) |
| | mdh | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (321 aa) |
| | sucC | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa) |
| | sucD | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (303 aa) |
| | Meso_3398 | TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component Transketolase, central region; KEGG: mlo:mll4301 alpha-ketoglutarate dehydrogenase. (994 aa) |
| | Meso_3399 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (428 aa) |
| | Meso_3400 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase glucose-inhibited division protein A fumarate reductase/succinate dehydrogenase flavoprotein-like pyridine nucleotide-disulphide oxidoreductase dimerisation region FAD dependent oxidoreductase; KEGG: mlo:mll4296 dihydrolipoamide dehydrogenase. (470 aa) |
| | Meso_3422 | PFAM: NAD-glutamate dehydrogenase; KEGG: mlo:mll4104 hypothetical protein. (1586 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | Meso_3434 | PFAM: NAD-dependent epimerase/dehydratase short-chain dehydrogenase/reductase SDR 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: bja:bll6807 dehydrogenase. (263 aa) |
| | Meso_3436 | PFAM: fructose-bisphosphate aldolase, class-I; KEGG: atc:AGR_L_2190 putative fructose bisphosphate aldolase. (341 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: sme:SMc03981 probable phosphoglycerate kinase protein; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | Meso_3439 | TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: mlo:mlr3750 glyceraldehyde-3-phosphate dehydrogenase(GAPDH); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa) |
| | Meso_3440 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (686 aa) |
| | pfp | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (388 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (536 aa) |
| | Meso_3505 | PFAM: Thiolase; KEGG: sme:SMc00262 putative 3-ketoacyl-CoA thiolase protein; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa) |
| | Meso_3546 | PFAM: NAD-dependent epimerase/dehydratase short-chain dehydrogenase/reductase SDR; KEGG: bmb:BruAb1_0238 oxidoreductase, short chain dehydrogenase/reductase family. (261 aa) |
| | Meso_3562 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: jan:Jann_2909 5-carboxymethyl-2-hydroxymuconate delta-isomerase. (232 aa) |
| | Meso_3563 | TIGRFAM: maleylacetoacetate isomerase; PFAM: glutathione S-transferase-like; KEGG: mlo:mlr1135 maleylacetoacetate isomerase. (216 aa) |
| | Meso_3565 | Gentisate 1,2-dioxygenase; PFAM: Cupin 2, conserved barrel; KEGG: jan:Jann_2910 cupin 2 protein. (367 aa) |
| | Meso_3566 | KEGG: cgb:cg3349 hypothetical protein. (203 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (206 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (277 aa) |
| | glk | TIGRFAM: glucokinase; PFAM: Glucokinase; KEGG: mlo:mlr4640 glucokinase (glk); Belongs to the bacterial glucokinase family. (342 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (137 aa) |
| | Meso_3617 | PFAM: Transketolase-like; KEGG: mlo:mll5765 transketolase. (281 aa) |
| | Meso_3618 | Transketolase subunit B; PFAM: Transketolase, central region Transketolase-like; KEGG: psp:PSPPH_1255 transketolase, C-terminal subunit, putative. (331 aa) |
| | Meso_3621 | PFAM: fumarate lyase; KEGG: cme:CMD058C fumarate hydratase precursor. (470 aa) |
| | Meso_3622 | PFAM: fumarate lyase; KEGG: bja:bll7942 probable 3-carboxy-cis,cis-muconate cycloisomerase. (456 aa) |
| | Meso_3627 | PFAM: aldehyde dehydrogenase; KEGG: mlo:mll2867 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (503 aa) |
| | Meso_3630 | PFAM: Rhodanese-like; KEGG: cfa:474515 similar to 3-mercaptopyruvate sulfurtransferase. (282 aa) |
| | Meso_3703 | 5-dehydro-2-deoxygluconokinase; PFAM: PfkB; KEGG: plu:plu1801 unnamed protein product; similar to myo-inositol catabolism protein IolC of Bacillus subtilis; Belongs to the carbohydrate kinase PfkB family. (630 aa) |
| | Meso_3726 | PFAM: amidohydrolase 2; KEGG: pfl:PFL_3557 transcriptional regulator, GntR family/amidohydrolase family protein. (283 aa) |
| | Meso_3747 | PFAM: Rhodanese-like; KEGG: bms:BR1055 rhodanese family protein. (290 aa) |
| | Meso_3751 | PFAM: Enoyl-CoA hydratase/isomerase 3-hydroxyacyl-CoA dehydrogenase-like 6-phosphogluconate dehydrogenase, NAD-binding 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: bpm:BURPS1710b_0633 enoyl-CoA hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase. (677 aa) |
| | Meso_3752 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bja:blr3445 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa) |
| | Meso_3758 | PFAM: dihydrodipicolinate synthetase; KEGG: jan:Jann_3748 dihydrodipicolinate synthetase; Belongs to the DapA family. (295 aa) |
| | Meso_3766 | PFAM: aldehyde dehydrogenase; KEGG: pub:SAR11_0766 succinate-semialdehyde dehydrogenase (NAD(P)). (483 aa) |
| | Meso_3770 | Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region; KEGG: bja:bll6697 putative glconolactonase. (323 aa) |
| | Meso_3785 | PFAM: Rhodanese-like; KEGG: sme:SMb21549 putative exported sulfurtransferase, rhodanese protein. (303 aa) |
| | Meso_3874 | TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; KEGG: hch:HCH_05488 carbamate kinase; Belongs to the carbamate kinase family. (303 aa) |
| | Meso_3877 | TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; KEGG: hch:HCH_01517 phosphoribosylpyrophosphate synthetase. (326 aa) |
| | Meso_3884 | TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase dihydrodipicolinate reductase; KEGG: mth:MTH1009 NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase. (346 aa) |
| | Meso_3888 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: bur:Bcep18194_A3918 D-isomer specific 2-hydroxyacid dehydrogenase. (336 aa) |
| | Meso_3910 | PFAM: Carboxymuconolactone decarboxylase; KEGG: bja:bll4600 4-carboxymuconolactone decarboxylase, putative. (264 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (732 aa) |
| | Meso_3943 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mlo:mlr5574 2-hydroxyacid dehydrogenase. (333 aa) |
| | Meso_3946 | 6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (472 aa) |
| | Meso_3989 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (480 aa) |
| | Meso_3991 | PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like nitrite and sulphite reductase 4Fe-4S region; KEGG: mlo:mll3230 sulfite reductase hemoprotein subunit. (556 aa) |
| | cysH | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (245 aa) |
| | Meso_4030 | PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr5329 NADP-dependent malic enzyme. (761 aa) |
| | Meso_4079 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mlo:mll5489 putative 2-hydroxyacid dehydrogenase. (318 aa) |
| | Meso_4101 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mll5584 enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
