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Krad_0003 Krad_0003 zwf zwf Krad_0143 Krad_0143 Krad_0165 Krad_0165 Krad_0597 Krad_0597 rbsK rbsK prs prs eno eno Krad_1118 Krad_1118 Krad_1119 Krad_1119 zwf-2 zwf-2 pgi pgi Krad_1524 Krad_1524 Krad_1536 Krad_1536 Krad_1917 Krad_1917 Krad_1918 Krad_1918 Krad_1919 Krad_1919 Krad_1920 Krad_1920 Krad_2086 Krad_2086 Krad_2157 Krad_2157 Krad_2434 Krad_2434 Krad_2483 Krad_2483 Krad_2922 Krad_2922 tal tal zwf-3 zwf-3 Krad_2925 Krad_2925 pgl pgl tpiA tpiA pgk pgk Krad_2931 Krad_2931 Krad_2959 Krad_2959 Krad_2980 Krad_2980 Krad_3234 Krad_3234 Krad_3319 Krad_3319 ppc ppc Krad_3522 Krad_3522 pckG pckG Krad_3734 Krad_3734 Krad_3870 Krad_3870 Krad_3895 Krad_3895 xylB xylB Krad_4124 Krad_4124 deoC deoC Krad_4226 Krad_4226 Krad_4229 Krad_4229 pfkA pfkA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
Krad_0003TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rha:RHA1_ro03668 phosphogluconate dehydrogenase (decarboxylating). (304 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (474 aa)
Krad_0143TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: nca:Noca_4438 phosphoglucomutase, alpha-D-glucose phosphate-specific. (551 aa)
Krad_0165TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; KEGG: sma:SAV7451 putative ribose-phosphate pyrophosphokinase. (312 aa)
Krad_0597TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: dra:DR1910 thermoresistant gluconokinase. (170 aa)
rbsKPfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (322 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
Krad_1118PFAM: PfkB domain protein; KEGG: rha:RHA1_ro02811 fructokinase. (316 aa)
Krad_1119TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sco:SCO5047 fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase. (346 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (480 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: pac:PPA2131 glucose-6-phosphate isomerase; Belongs to the GPI family. (561 aa)
Krad_15246-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (490 aa)
Krad_1536PFAM: PfkB domain protein; KEGG: tfu:Tfu_0696 putative 6-phosphofructokinase : 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (319 aa)
Krad_1917PFAM: triosephosphate isomerase; KEGG: sco:SCO0578 triosephosphate isomerase. (264 aa)
Krad_1918Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; KEGG: msm:MSMEG_3272 ribose 5-phosphate isomerase. (167 aa)
Krad_1919PFAM: Dak kinase; Dak phosphatase; KEGG: sme:SMb20767 putative dihydroxyacetone (glycerone) kinase protein. (569 aa)
Krad_1920PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb20768 hypothetical protein. (338 aa)
Krad_2086PFAM: carbohydrate kinase FGGY; KEGG: rxy:Rxyl_0833 carbohydrate kinase, FGGY; Belongs to the FGGY kinase family. (506 aa)
Krad_2157TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; KEGG: aau:AAur_1469 putative fructose/tagatose bisphosphate aldolase. (281 aa)
Krad_2434Pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: mka:MK0252 phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (434 aa)
Krad_2483TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: nfa:nfa48000 putative fructose-1,6-bisphosphatase. (350 aa)
Krad_2922Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (697 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (373 aa)
zwf-3Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (513 aa)
Krad_2925TIGRFAM: OpcA protein; KEGG: art:Arth_2093 oxppcycle protein. (406 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (249 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: nca:Noca_2531 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (412 aa)
Krad_2931TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: art:Arth_2087 glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
Krad_2959TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: art:Arth_1693 pyruvate kinase; Belongs to the pyruvate kinase family. (505 aa)
Krad_2980PFAM: ribulose-phosphate 3-epimerase; KEGG: aau:AAur_1824 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa)
Krad_32346-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (343 aa)
Krad_3319PFAM: ROK family protein; KEGG: tfu:Tfu_1811 polyphosphate glucokinase/transcriptional regulator. (268 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (954 aa)
Krad_3522Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; KEGG: tfu:Tfu_2202 ribose/galactose isomerase:ribose 5-phosphate isomerase, actinobacteria. (162 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (625 aa)
Krad_3734PFAM: ROK family protein; KEGG: nca:Noca_4485 ROK family protein. (331 aa)
Krad_3870TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: tfu:Tfu_0016 mannose-6-phosphate isomerase, type I. (402 aa)
Krad_3895PFAM: carbohydrate kinase FGGY; KEGG: gka:GK1941 gluconokinase; Belongs to the FGGY kinase family. (524 aa)
xylBTIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: ace:Acel_2065 xylulokinase. (465 aa)
Krad_4124Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (225 aa)
Krad_4226Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; KEGG: msm:MSMEG_3272 ribose 5-phosphate isomerase. (167 aa)
Krad_4229KEGG: tfu:Tfu_2315 putative secreted protein. (340 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (461 aa)
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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