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ndk ndk Krad_0123 Krad_0123 Krad_0187 Krad_0187 tmk tmk adk adk Krad_0854 Krad_0854 ppk ppk thiL thiL pyrH pyrH Krad_2792 Krad_2792 Krad_2992 Krad_2992 cmk cmk
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa)
Krad_0123PFAM: protein of unknown function DUF344; KEGG: fal:FRAAL4412 conserved hypothetical protein; putative P-loop containing nucleotide triphosphate hydrolase domain. (296 aa)
Krad_0187PFAM: protein of unknown function DUF344; KEGG: msm:MSMEG_0891 polyphosphate kinase 2. (296 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (662 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (191 aa)
Krad_0854TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase. (279 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (721 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (314 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (253 aa)
Krad_2792KEGG: lxx:Lxx21810 hypothetical protein. (224 aa)
Krad_2992Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (173 aa)
cmkTIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: art:Arth_1536 cytidylate kinase. (263 aa)
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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