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lysA lysA Krad_0182 Krad_0182 Krad_3071 Krad_3071 ppc ppc purK purK pckG pckG pyrF pyrF Krad_0160 Krad_0160 Krad_2990 Krad_2990 trpC trpC Krad_2492 Krad_2492 Krad_2069 Krad_2069 Krad_2062 Krad_2062 hemE hemE Krad_1287 Krad_1287 Krad_1228 Krad_1228
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
Krad_0182PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: mbb:BCG_0905c putative pyruvate or indole-3-pyruvate decarboxylase pdc. (561 aa)
Krad_3071PFAM: amidohydrolase 2; KEGG: aba:Acid345_0658 amidohydrolase 2. (387 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (954 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (377 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (625 aa)
pyrFTIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: sma:SAV6869 putative orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (286 aa)
Krad_0160Orn/Lys/Arg decarboxylase major region; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; Orn/Lys/Arg decarboxylase major region; aminotransferase class-III; Orn/Lys/Arg decarboxylase domain protein; Soluble liver antigen/liver pancreas antigen; KEGG: nfa:nfa6850 putative Orn/Lys/Arg decarboxylase. (486 aa)
Krad_2990Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (429 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; KEGG: sco:SCO2039 indoleglycerol phosphate synthase; Belongs to the TrpC family. (274 aa)
Krad_2492Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (170 aa)
Krad_2069KEGG: rha:RHA1_ro04511 hypothetical protein. (179 aa)
Krad_2062PFAM: amidohydrolase 2; KEGG: fal:FRAAL5959 hypothetical protein. (273 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa)
Krad_1287PFAM: amidohydrolase 2. (303 aa)
Krad_1228TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase central region; KEGG: art:Arth_2645 2-oxoglutarate dehydrogenase, E1 subunit. (1287 aa)
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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