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Krad_0085 Krad_0085 Krad_0981 Krad_0981 Krad_1206 Krad_1206 Krad_1285 Krad_1285 Krad_1289 Krad_1289 Krad_2472 Krad_2472 Krad_2969 Krad_2969 hisF hisF hisG hisG Krad_2976 Krad_2976 hisA hisA hisH hisH hisB hisB hisC hisC hisD-2 hisD-2 Krad_3928 Krad_3928 pat pat hutI hutI hutU hutU Krad_4453 Krad_4453
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Krad_0085PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: rha:RHA1_ro02017 probable L-amino-acid oxidase. (536 aa)
Krad_0981PFAM: aminotransferase class V; KEGG: mva:Mvan_5482 aminotransferase, class V. (369 aa)
Krad_1206TIGRFAM: histidinol-phosphate phosphatase, putative; PFAM: inositol monophosphatase; KEGG: art:Arth_2655 histidinol-phosphate phosphatase, putative. (275 aa)
Krad_1285PFAM: phenylalanine/histidine ammonia-lyase; KEGG: dra:DRA0147 histidine ammonia-lyase. (475 aa)
Krad_1289PFAM: phenylalanine/histidine ammonia-lyase; KEGG: sma:SAV3504 histidine ammonia-lyase. (497 aa)
Krad_2472PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: msm:MSMEG_2035 amine oxidase [flavin-containing] B. (459 aa)
Krad_2969Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (102 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa)
Krad_2976PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: tfu:Tfu_0175 phosphoribosyl-ATP pyrophosphatase; Belongs to the PRA-PH family. (63 aa)
hisATIGRFAM: bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein; KEGG: art:Arth_1473 bifunctional HisA/TrpF protein. (267 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa)
hisBPFAM: imidazoleglycerol-phosphate dehydratase; KEGG: art:Arth_1471 imidazoleglycerol-phosphate dehydratase. (199 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: nca:Noca_3044 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (378 aa)
hisD-2Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (443 aa)
Krad_3928PFAM: aldehyde dehydrogenase; KEGG: nca:Noca_3529 betaine-aldehyde dehydrogenase. (445 aa)
patHistidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (376 aa)
hutITIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: art:Arth_1313 imidazolonepropionase. (407 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (554 aa)
Krad_4453TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; KEGG: nfa:nfa12280 putative histidine ammonia-lyase. (514 aa)
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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