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Krad_0201 Krad_0201 acsA acsA Krad_0532 Krad_0532 Krad_0766 Krad_0766 Krad_0865 Krad_0865 Krad_1140 Krad_1140 Krad_1566 Krad_1566 Krad_1601 Krad_1601 Krad_1602 Krad_1602 Krad_1603 Krad_1603 Krad_1637 Krad_1637 Krad_2133 Krad_2133 Krad_2140 Krad_2140 Krad_2146 Krad_2146 Krad_2227 Krad_2227 Krad_2750 Krad_2750 gcvP gcvP gcvH gcvH Krad_3278 Krad_3278 Krad_3291 Krad_3291 Krad_3296 Krad_3296 Krad_3488 Krad_3488 Krad_3519 Krad_3519 Krad_3579 Krad_3579 Krad_3912 Krad_3912 glyA glyA purU purU Krad_3989 Krad_3989 Krad_4028 Krad_4028 gcvT gcvT Krad_4157 Krad_4157 Krad_4424 Krad_4424
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Krad_0201TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: pac:PPA0371 KHG/KDPG aldolase. (223 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
Krad_0532Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: atc:AGR_L_1864 biotin carboxylase protein A2. (575 aa)
Krad_0766PFAM: FAD linked oxidase domain protein; KEGG: fal:FRAAL3861 putative glycolate oxidoreductase (partial match). (441 aa)
Krad_0865PFAM: Catalase domain protein; KEGG: nfa:nfa55390 putative catalase; Belongs to the catalase family. (551 aa)
Krad_1140TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: mpa:MAP0829 citrate synthase; Belongs to the citrate synthase family. (441 aa)
Krad_1566TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: art:Arth_1644 aconitate hydratase 1. (949 aa)
Krad_1601PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: mkm:Mkms_5307 molybdopterin oxidoreductase Fe4s4 region. (189 aa)
Krad_1602Formate dehydrogenase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: mmc:Mmcs_5220 formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (956 aa)
Krad_1603PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mpa:MAP0369 formate dehydrogenase, iron-sulfur subunit (formate dehydrogenase beta subunit). (376 aa)
Krad_1637Glutamate--putrescine ligase; PFAM: glutamine synthetase catalytic region; KEGG: sco:SCO1613 putative glutamine synthetase. (483 aa)
Krad_2133TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: vfi:VF0090 2-dehydro-3-deoxyphosphogluconate aldolase. (200 aa)
Krad_2140PFAM: Xylose isomerase domain protein TIM barrel; KEGG: rle:RL3799 putative hydroxypyruvate isomerase; Belongs to the hyi family. (273 aa)
Krad_2146PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rha:RHA1_ro02575 probable 2-hydroxy-3-oxopropionate reductase. (294 aa)
Krad_2227TIGRFAM: malate synthase A; PFAM: malate synthase; KEGG: tfu:Tfu_0819 malate synthase; Belongs to the malate synthase family. (526 aa)
Krad_2750PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: hch:HCH_01003 probable mercuric reductase. (502 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
Krad_3278TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: nca:Noca_2304 dihydrolipoamide dehydrogenase. (477 aa)
Krad_3291TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: ace:Acel_0923 glutamine synthetase, type I. (474 aa)
Krad_3296TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: tfu:Tfu_0982 glutamine synthetase type I. (447 aa)
Krad_3488TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: tfu:Tfu_2856 acetate--CoA ligase. (656 aa)
Krad_3519PFAM: glycerate kinase; KEGG: aau:AAur_3509 glycerate kinase; Belongs to the glycerate kinase type-1 family. (397 aa)
Krad_3579PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sco:SCO4323 hydrolase. (241 aa)
Krad_3912Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: sma:SAV3337 putative acyl-CoA carboxylase, alpha subunit. (634 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (434 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (285 aa)
Krad_3989PFAM: carboxyl transferase; KEGG: sco:SCO4926 propionyl-CoA carboxylase complex B subunit. (534 aa)
Krad_4028TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: aau:AAur_2140 putative acetyl-coa acetyltransferase (thiolase); Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (391 aa)
Krad_4157PFAM: Xylose isomerase domain protein TIM barrel; KEGG: rha:RHA1_ro05268 probable hydroxypyruvate isomerase; Belongs to the hyi family. (264 aa)
Krad_4424PFAM: glutamine synthetase catalytic region; KEGG: mva:Mvan_4030 glutamine synthetase, catalytic region. (721 aa)
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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